2024
Presentation and patterns of reinterventions after revascularization in patients with premature Peripheral Arterial Disease
Sivakumar A, Satam K, Wu Z, Alameddine D, Aboian E, Chaer R, Schermerhorn M, Moreira C, Guzman R, Ochoa Chaar C. Presentation and patterns of reinterventions after revascularization in patients with premature Peripheral Arterial Disease. Journal Of Vascular Surgery 2024 PMID: 39002606, DOI: 10.1016/j.jvs.2024.07.021.Peer-Reviewed Original ResearchPremature peripheral arterial diseaseLower extremity revascularizationOlder patientsPeripheral arterial diseaseArtery diseaseRetrospective review of consecutive patientsReview of consecutive patientsDistressed Communities IndexAge of presentationFrequency of reinterventionsEnd-stage renal diseaseKaplan-Meier curvesOutcomes of lower extremity revascularizationLong-term outcomesCoronary artery diseaseMALE-free survivalAdverse limb eventsOverall survivalReintervention rateConsecutive patientsFrequent reinterventionsPerioperative complicationsRetrospective reviewNo significant differenceInstitutional experienceArtificial Intelligence Improves Initial Evaluation and Follow-up of Patients With AAAs
Kostiuk V, Rodriguez P, Loh S, Wilson E, Yao K, Bader J, Mojibian H, Fischer U, Guzman R, Kuwayama D, Chaar C, Aboian E. Artificial Intelligence Improves Initial Evaluation and Follow-up of Patients With AAAs. Journal Of Vascular Surgery 2024, 79: e131-e132. DOI: 10.1016/j.jvs.2024.03.163.Peer-Reviewed Original ResearchOpen and Endovascular Treatment of the Common Femoral Artery in a Tertiary Care Center
Wells N, Hundito A, Tuttle M, Alameddine D, Aboian E, Arhuidese I, Fischer U, Perez-Lozada J, Guzman R, Chaar C. Open and Endovascular Treatment of the Common Femoral Artery in a Tertiary Care Center. Journal Of Vascular Surgery 2024, 79: e45-e46. DOI: 10.1016/j.jvs.2024.03.032.Peer-Reviewed Original ResearchEndoscopic Transaxillary First Rib Resection
Setia O, Strosberg D, Blasberg J, Schwartz J, Tonnessen B, Cardella J, Zwibelman H, Guzman R. Endoscopic Transaxillary First Rib Resection. Journal Of Vascular Surgery 2024, 79: e115. DOI: 10.1016/j.jvs.2024.03.139.Peer-Reviewed Original ResearchThe radiographic relationship of the femoral head, inguinal ligament, and common femoral artery bifurcation for optimal vascular access
Brahmandam A, Huttler J, Bellamkonda K, Setia O, Cardella J, Stewart W, Guzman R, Ochoa Chaar C. The radiographic relationship of the femoral head, inguinal ligament, and common femoral artery bifurcation for optimal vascular access. Journal Of Vascular Surgery 2024, 79: a17-a18. DOI: 10.1016/j.jvs.2024.04.032.Peer-Reviewed Original ResearchComparative Outcomes of Peripheral Vascular Intervention in Patients Discharged on Clopidogrel in Combination With Factor Xa Inhibitors or Aspirin
Huttler J, Rodriguez P, Dandu C, Piazza G, Kabbani L, Kashyap V, Slade M, Zwibelman H, Guzman R, Chaar C. Comparative Outcomes of Peripheral Vascular Intervention in Patients Discharged on Clopidogrel in Combination With Factor Xa Inhibitors or Aspirin. Journal Of Vascular Surgery 2024, 79: e290-e292. DOI: 10.1016/j.jvs.2024.03.375.Peer-Reviewed Original ResearchThe Incidence and Significance of Bleeding in Patients With Advanced Peripheral Arterial Disease
Hundito A, Wells N, Tuttle M, Alameddine D, Huttler J, Slade M, Strosberg D, Lee A, Guzman R, Chaar C. The Incidence and Significance of Bleeding in Patients With Advanced Peripheral Arterial Disease. Journal Of Vascular Surgery 2024, 79: e60-e61. DOI: 10.1016/j.jvs.2024.03.051.Peer-Reviewed Original ResearchHyperlipidemia and Comprehensive Vascular Events (CVEs) - a Novel Outcome Measure for Peripheral Arterial Disease
Tuttle M, Wells N, Hundito A, Alameddine D, Huttler J, Mena-Hurtado C, Turner J, Inzucchi S, Dardik A, Guzman R, Chaar C. Hyperlipidemia and Comprehensive Vascular Events (CVEs) - a Novel Outcome Measure for Peripheral Arterial Disease. Journal Of Vascular Surgery 2024, 79: e176-e177. DOI: 10.1016/j.jvs.2024.03.220.Peer-Reviewed Original ResearchIntravascular Ultrasound Use is Associated with Improved Patency in Lower Extremity Peripheral Arterial Interventions
Brahmandam A, Kim T, Parziale S, Deng Y, Setia O, Tonnessen B, Ochoa Chaar C, Guzman R, Aboian E. Intravascular Ultrasound Use is Associated with Improved Patency in Lower Extremity Peripheral Arterial Interventions. Annals Of Vascular Surgery 2024, 106: 410-418. PMID: 38810722, DOI: 10.1016/j.avsg.2024.03.008.Peer-Reviewed Original ResearchChronic limb-threatening ischemiaChronic limb threatening ischemia patientsGeneralized estimating equationsPeripheral vascular interventionsPeripheral arterial diseaseAssociated with improved patencyPredictors of 1-year outcomeIntravascular ultrasound useVascular Quality InitiativeSubgroup analysisAdjunctive useD lesionsTASC CPropensity matchingTreatment modalitiesTrans-Atlantic Inter-Society Consensus (TASC) classificationMajor amputationLimb-threatening ischemiaBalloon angioplastyIntravascular ultrasoundImproved patencyUltrasound useOne-year followQuality InitiativePredictors of patencyClinical Implications of Low Body Mass Index on Endovascular Lower Extremity Revascularization
Pinto Rodriguez P, Alameddine D, Huttler J, Damara F, Slade M, Cardella J, Guzman R, Chaar C. Clinical Implications of Low Body Mass Index on Endovascular Lower Extremity Revascularization. Annals Of Vascular Surgery 2024, 106: 350-359. PMID: 38810726, DOI: 10.1016/j.avsg.2024.02.031.Peer-Reviewed Original ResearchPeripheral vascular interventionsPeripheral arterial diseaseLower body mass indexUnderweight patientsLong-term outcomesBody mass indexNonobese patientsMass indexRetrospective analysis of patientsRate of thrombotic complicationsHigher 30-day mortalityRates of amputation-free survivalRate of reinterventionOutcomes of patientsPeripheral arterial disease patientsAnalysis of patientsKaplan-Meier analysisImpact of malnutritionBaseline demographic characteristicsChronic limb-threatening ischemiaEpidemic of obesityOptimization of nutritionLonger hospital lengthAdverse limb eventsAmputation-free survivalFasting Duration Prior to Venography Is Associated with Stent Size in Patients with Iliac Vein Compression
Schultz K, Rodriguez P, Hamdi S, Attaran R, Lozada J, Huber S, Tonnessen B, Aboian E, Guzman R, Chaar C. Fasting Duration Prior to Venography Is Associated with Stent Size in Patients with Iliac Vein Compression. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2024, 12: 101774. DOI: 10.1016/j.jvsv.2024.101774.Peer-Reviewed Original ResearchClinician perspectives regarding CYP2C19 genotype testing in patients with critical limb ischemia: A Delphi approach.
Regan C, Scierka L, Dardik A, Tonnessen B, Iyad Ochoa Chaar C, Ionescu C, Aboian E, Cardella J, Nassiri N, Guzman R, Attaran R, Nagpal S, Shah S, Smolderen K, Mena-Hurtado C. Clinician perspectives regarding CYP2C19 genotype testing in patients with critical limb ischemia: A Delphi approach. Vascular 2024, 17085381241246318. PMID: 38669051, DOI: 10.1177/17085381241246318.Peer-Reviewed Original ResearchDual antiplatelet therapyPeripheral arterial diseaseCYP2C19 testingCYP2C19 mutationsHeterogeneity of treatment effectsPeripheral vascular interventionsConsensus statementKnowledge questionsAntiplatelet therapyGenetic testingVascular surgeryAcademic health systemBarriers to implementationInterquartile rangeCYP2C19 genotype testingVascular diseaseInterventional cardiologyModified Delphi methodPatient's metabolic statusManagement of patientsCritical limb ischemiaPerceived barriersPeripheral vascular diseaseArterial vascular diseaseClinician perspectivesLong-term limb salvage and functional outcomes for patients undergoing partial calcanectomy.
Kostiuk V, Gazes M, Fereydooni S, Chaar C, Guzman R, Tonnessen B. Long-term limb salvage and functional outcomes for patients undergoing partial calcanectomy. Vascular 2024, 17085381241247627. PMID: 38631330, DOI: 10.1177/17085381241247627.Peer-Reviewed Original ResearchMajor limb amputationPeripheral arterial diseasePartial calcanectomyAmbulatory statusLimb amputationRisk of major limb amputationNon-invasive vascular testingRisk of amputationVascular testingAnkle brachial indexEnd-stage renal diseaseAbsence of peripheral arterial diseaseMultivariate logistic regression analysisLogistic regression analysisAssociated with increased mortalityAmputation-free survivalHeel ulcersChronic heel ulcersLower extremity revascularizationBrachial indexSecondary outcomesPrimary outcomePodiatric procedureAmputationCalcanectomyPerioperative complications of minor and major reinterventions for peripheral arterial disease.
Huttler J, Satam K, Kim T, Zhuo H, Zhang Y, Aboian E, Guzman R, Chaar C. Perioperative complications of minor and major reinterventions for peripheral arterial disease. Vascular 2024, 17085381241246907. PMID: 38597200, DOI: 10.1177/17085381241246907.Peer-Reviewed Original ResearchCatheter-directed thrombolysisLower-extremity revascularizationPeripheral arterial diseaseSurgical reinterventionPerioperative morbidityPerioperative outcomesAssociated with greater perioperative morbiditySubgroup analysisArtery diseaseReturn to the ORRetrospective review of electronic medical recordsPost-operative bleedingReview of electronic medical recordsIncreased perioperative morbidityAcute renal failureVascular Surgery guidelinesTertiary care centerSurgery guidelinesOpen surgeryPerioperative mortalityPerioperative complicationsRetrospective reviewWound infectionRenal failureReinterventionAnticoagulation in Patients with Premature Peripheral Artery Disease Undergoing Lower Extremity Revascularization
Kim T, DeWan A, Murray M, Wang H, Mani A, Mena-Hurtado C, Guzman R, Ochoa Chaar C. Anticoagulation in Patients with Premature Peripheral Artery Disease Undergoing Lower Extremity Revascularization. Annals Of Vascular Surgery 2024, 105: 150-157. PMID: 38593922, DOI: 10.1016/j.avsg.2024.02.006.Peer-Reviewed Original ResearchPremature peripheral arterial diseaseAntiplatelet therapyVascular Quality InitiativeArtery diseaseAdjunct to antiplatelet therapyReturn to the operating roomPost-operative anticoagulationCompared to patientsPostoperative antiplatelet therapyOne-year outcomesCongestive heart failureLower extremity revascularizationMajor adverse limb eventsCoronary artery diseaseEffects of anticoagulantsAmputation-free survivalEarly onset of diseaseAdverse limb eventsPeripheral vascular interventionsOnset of diseasePeripheral arterial diseaseLower-extremity revascularizationPropensity score matchingPerioperative mortalityBaseline characteristicsGenerating better data
Eldrup-Jorgensen J, Guzman R, Mills J. Generating better data. Journal Of Vascular Surgery 2024, 79: 984-985. PMID: 38519217, DOI: 10.1016/j.jvs.2023.11.038.Peer-Reviewed Original ResearchSmooth muscle cell-specific matrix metalloproteinase 3 deletion reduces osteogenic transformation and medial artery calcification
Xie Y, Lin T, Jin Y, Berezowitz A, Wang X, Lu J, Cai Y, Guzman R. Smooth muscle cell-specific matrix metalloproteinase 3 deletion reduces osteogenic transformation and medial artery calcification. Cardiovascular Research 2024, 120: 658-670. PMID: 38454645, PMCID: PMC11074797, DOI: 10.1093/cvr/cvae035.Peer-Reviewed Original ResearchSmooth muscle cellsPeripheral arterial diseaseVascular smooth muscle cellsMedial calcificationMMP-3Osteogenic transformationRodent modelsAssociated with increased morbiditySmooth muscle cell calcificationChronic kidney diseaseEx vivo organ culture modelMMP-3 expressionOrgan culture modelMedial arterial calcificationTargeting MMP-3Matrix metalloproteinase 3MMP-3 proteinArtery calcificationArtery diseaseKidney diseaseVascular calcificationMuscle cellsTherapeutic strategiesCalcification mediumVitamin D3The radiographic relationship of the femoral head, inguinal ligament, and common femoral artery bifurcation for optimal vascular access
Brahmandam A, Huttler J, Bellamkonda K, Setia O, Cardella J, Stewart W, Guzman R, Chaar C. The radiographic relationship of the femoral head, inguinal ligament, and common femoral artery bifurcation for optimal vascular access. JVS Vascular Science 2024, 5: 100196. PMID: 38633882, PMCID: PMC11022081, DOI: 10.1016/j.jvssci.2024.100196.Peer-Reviewed Original Research
2023
The Utilization of Protamine during Peripheral Vascular Interventions in the VQI
Ali S, Shebl F, Aboian E, Strosberg D, Fischer U, Cardella J, Guzman R, Ochoa Chaar C. The Utilization of Protamine during Peripheral Vascular Interventions in the VQI. Annals Of Vascular Surgery 2023, 101: 72-79. PMID: 38110083, DOI: 10.1016/j.avsg.2023.10.019.Peer-Reviewed Original ResearchPeripheral vascular interventionsAdjusted rate ratiosProtamine useCardiac complicationsPropensity matchingVascular interventionsChronic obstructive pulmonary diseasePropensity scoreCharacteristics of patientsPeripheral arterial diseaseCongestive heart failureObstructive pulmonary diseaseMultivariable Poisson regressionUse of protamineSignificant differencesMedical comorbiditiesP2Y12 inhibitorsPerioperative bleedingPerioperative medicationsPerioperative outcomesDistal embolizationPatient comorbiditiesCarotid surgeryHeart failurePulmonary diseaseThe development of a novel endovascular grasper for challenging inferior vena cava filter retrieval
Ochoa Chaar C, Kostiuk V, Rodriguez P, Kim T, Rathbone D, Ghandour L, Burns R, Thorn S, Sinusas A, Guzman R, Dardik A. The development of a novel endovascular grasper for challenging inferior vena cava filter retrieval. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2023, 12: 101731. PMID: 38081514, DOI: 10.1016/j.jvsv.2023.101731.Peer-Reviewed Original Research