Featured Publications
Neural network predicts need for red blood cell transfusion for patients with acute gastrointestinal bleeding admitted to the intensive care unit
Shung D, Huang J, Castro E, Tay JK, Simonov M, Laine L, Batra R, Krishnaswamy S. Neural network predicts need for red blood cell transfusion for patients with acute gastrointestinal bleeding admitted to the intensive care unit. Scientific Reports 2021, 11: 8827. PMID: 33893364, PMCID: PMC8065139, DOI: 10.1038/s41598-021-88226-3.Peer-Reviewed Original ResearchConceptsAcute gastrointestinal bleedingRed blood cell transfusionBlood cell transfusionGastrointestinal bleedingHigh-risk patientsCell transfusionRed blood cellsPatient cohortIntensive Care III (MIMIC-III) critical care databaseIntensive care unit staySevere acute gastrointestinal bleedingPacked red blood cellsBlood cellsCommon gastrointestinal causesLaboratory test featuresTime-updated dataIntensive care unitValidation patient cohortCritical care databaseLarge urban hospitalMedical Information MartInternal validation setGastrointestinal causesUnit stayCare unitMachine Learning Models for Prediction of Posttreatment Recurrence in Early-Stage Hepatocellular Carcinoma Using Pretreatment Clinical and MRI Features: A Proof-of-Concept Study.
Iseke S, Zeevi T, Kucukkaya AS, Raju R, Gross M, Haider SP, Petukhova-Greenstein A, Kuhn TN, Lin M, Nowak M, Cooper K, Thomas E, Weber MA, Madoff DC, Staib L, Batra R, Chapiro J. Machine Learning Models for Prediction of Posttreatment Recurrence in Early-Stage Hepatocellular Carcinoma Using Pretreatment Clinical and MRI Features: A Proof-of-Concept Study. American Journal Of Roentgenology 2022, 220: 245-255. PMID: 35975886, PMCID: PMC10015590, DOI: 10.2214/ajr.22.28077.Peer-Reviewed Original ResearchConceptsEarly-stage hepatocellular carcinomaLiver transplantHepatocellular carcinomaImaging featuresPosttreatment recurrenceOrgan allocationMean AUCLiver transplant eligibilityPretreatment clinical characteristicsPretreatment MRI examinationsKaplan-Meier analysisKaplan-Meier curvesClinical characteristicsImaging surveillanceTherapy allocationTransplant eligibilityUnderwent treatmentClinical parametersRetrospective studyUnpredictable complicationMRI dataConcept studyPoor survivalClinical impactPretreatment MRI
2020
Fibronodular hepatocellular carcinoma—a new variant of liver cancer: clinical, pathological and radiological correlation
Tefera J, Revzin M, Chapiro J, Savic L, Mulligan D, Batra R, Taddei T, Jain D, Zhang X. Fibronodular hepatocellular carcinoma—a new variant of liver cancer: clinical, pathological and radiological correlation. Journal Of Clinical Pathology 2020, 74: 31-35. PMID: 32430483, PMCID: PMC7674234, DOI: 10.1136/jclinpath-2020-206574.Peer-Reviewed Original ResearchConceptsAdvanced Barcelona Clinic Liver Cancer stageBarcelona Clinic Liver Cancer stageScirrhous HCCMultiple rounded nodulesNon-peripheral washoutLiver Cancer stageRadiological featuresClinical featuresRadiological correlationCarcinoma variantsCancer stageHCC casesHepatocellular carcinomaLiver cancerFibrotic liverConventional HCCHCCLower ratesHigh rateRounded nodulesProgressionDistinct patternsCarcinomaSpecific variantsLesions
2015
Rapid Resolution of Donor‐Derived Glomerular Fibrin Thrombi After Deceased Donor Kidney Transplantation
Batra R, Heilman R, Smith M, Thomas L, Khamash H, Katariya N, Hewitt W, Singer A, Mathur A, Huskey J, Chakkera H, Moss A, Reddy K. Rapid Resolution of Donor‐Derived Glomerular Fibrin Thrombi After Deceased Donor Kidney Transplantation. American Journal Of Transplantation 2015, 16: 1015-1020. PMID: 26689853, DOI: 10.1111/ajt.13561.Peer-Reviewed Original ResearchConceptsGlomerular fibrin thrombiControl groupProtocol biopsiesDeceased donorsFibrin thrombiDeceased donor kidney transplantationDelayed graft functionDonor kidney transplantationSevere interstitial fibrosisGraft functionPostreperfusion biopsiesGraft survivalKidney transplantationSerum creatinineTubular atrophyStudy cohortGlomerular thrombiHistologic outcomesInterstitial fibrosisPreimplantation biopsyRapid resolutionBiopsyThrombusSafe practiceTransplantationTransplanting Kidneys from Deceased Donors With Severe Acute Kidney Injury
Heilman R, Smith M, Kurian S, Huskey J, Batra R, Chakkera H, Katariya N, Khamash H, Moss A, Salomon D, Reddy K. Transplanting Kidneys from Deceased Donors With Severe Acute Kidney Injury. American Journal Of Transplantation 2015, 15: 2143-2151. PMID: 25808278, DOI: 10.1111/ajt.13260.Peer-Reviewed Original ResearchConceptsStandard criteria donorsAcute kidney injuryDeceased donorsAKI groupKidney injuryAcute Kidney Injury Network (AKIN) stagingSevere acute kidney injuryDeceased donor kidney transplantAcute renal replacement therapyDonor transplant recipientsTerminal serum creatinineRenal replacement therapyDonor kidney transplantsAKI donorsProtocol biopsiesGraft survivalTransplant recipientsKidney transplantSerum creatinineCriteria donorsReplacement therapyExcellent outcomesDonor cohortGene expression profilingKidney
2014
Kidney Transplant Program at the Mayo Clinic in Arizona.
Heilman RL, Khamash HA, Huskey JL, Chakkera HA, Batra RK, Katariya NN, Singer AL, Mathur AK, Moss AA, Reddy KS. Kidney Transplant Program at the Mayo Clinic in Arizona. Clinical Transplants 2014, 61-8. PMID: 26281128.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAdultAge FactorsAgedArizonaDonor SelectionFemaleGraft RejectionGraft SurvivalHumansImmunosuppressive AgentsKidney Failure, ChronicKidney TransplantationMaleMiddle AgedProgram EvaluationRegistriesRisk FactorsTime FactorsTissue and Organ ProcurementTissue DonorsTreatment OutcomeWaiting ListsYoung AdultConceptsDeceased donor kidney transplantDonor kidney transplantsKidney transplantGraft survivalAlemtuzumab inductionDonor transplantsMayo ClinicOlder kidney transplant recipientsHigh kidney donor profile indexKidney Donor Profile IndexSteroid avoidance immunosuppressionAcute kidney injuryDelayed graft functionKidney transplant recipientsKidney transplant programGlomerular filtration rateTime of transplantationDeceased donor transplantsPublic health servicesGraft functionSevere AKIKidney injurySteroid avoidanceTransplant recipientsBiopsy findings