2022
Long‐term risk of arch complications in Loeys Dietz syndrome patients undergoing proximal ascending aortic replacement
Weininger G, Zafar M, Ziganshin BA, Mori M, Papanikolaou D, Sekar RB, Amabile A, Degife E, O'Marr J, Geirsson A, Elefteriades JA, Assi R, Vallabhajosyula P. Long‐term risk of arch complications in Loeys Dietz syndrome patients undergoing proximal ascending aortic replacement. Journal Of Cardiac Surgery 2022, 37: 3688-3692. PMID: 35989525, DOI: 10.1111/jocs.16855.Peer-Reviewed Original ResearchConceptsLoeys-Dietz syndromeProximal aortic replacementAortic replacementLDS patientsLong-term riskLoeys-Dietz syndrome patientsPathogenic variantsUnknown significanceLower long-term riskRare connective tissue disorderAscending Aortic ReplacementTotal arch replacementAortic valve replacementRecords of patientsConnective tissue disordersWhole-exome genetic testingArch replacementMedian followLatest followValve replacementOperative coursePatient chartsAortic diameterAortic dimensionsAortic arch
2020
Cine-Computed Tomography for the Evaluation of Prosthetic Heart Valve Function
Hsu C, Bourganos K, Zafar MA, Huber S, Buntin J, Ziganshin BA, Mojibian H, Elefteriades JA. Cine-Computed Tomography for the Evaluation of Prosthetic Heart Valve Function. Cardiology 2020, 145: 439-445. PMID: 32454507, DOI: 10.1159/000507182.Peer-Reviewed Original ResearchConceptsAortic valve replacementAortic stenosisTransvalvular velocityValve functionECG-gated computed tomographyProsthetic heart valve functionProsthetic valve dysfunctionProsthetic valve functionCine CTHeart valve functionAVR patientsValve thrombosisCardiac eventsRepeat surgeryValve dysfunctionValve replacementSingle surgeonSurgical interventionRepeat evaluationProsthetic valvesComputed tomographyLeaflet excursionFurther evaluationLeaflet functionPatientsNonusefulness of Antithrombotic Therapy After Surgical Bioprosthetic Aortic Valve Replacement
Gryaznov AA, Saeyeldin A, Abdelbaky M, Zafar MA, Tanweer M, Papanikolaou D, Imran M, Li Y, Ziganshin BA, Elefteriades JA. Nonusefulness of Antithrombotic Therapy After Surgical Bioprosthetic Aortic Valve Replacement. The American Journal Of Cardiology 2020, 129: 71-78. PMID: 32605717, DOI: 10.1016/j.amjcard.2020.05.018.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAnticoagulantsAortic ValveAortic Valve InsufficiencyAortic Valve StenosisAspirinAtrial FibrillationBicuspid Aortic Valve DiseaseBioprosthesisCoronary Artery DiseaseFactor Xa InhibitorsFemaleHeart Valve DiseasesHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHemorrhageHumansKaplan-Meier EstimateMaleMiddle AgedMortalityPlatelet Aggregation InhibitorsPostoperative CareProportional Hazards ModelsPurinergic P2Y Receptor AntagonistsStrokeThromboembolismWarfarinYoung AdultConceptsAortic valve replacementBiological aortic valve replacementAntithrombotic regimensValve replacementSurgical bioprosthetic aortic valve replacementCox proportional hazards regression modelSurgical aortic valve replacementBioprosthetic aortic valve replacementConsecutive adult patientsCoronary artery diseaseKaplan-Meier analysisIncidence of deathHazards regression modelsAntiplatelet groupAVR patientsRoutine anticoagulationAntithrombotic therapyCardiovascular eventsThromboembolic eventsAdult patientsAdverse eventsAnticoagulation groupArtery diseaseTreatment regimensTherapy group
2019
Fate of preserved bicuspid valves at time of ascending aortic aneurysmectomy
Vinholo T, Zafar MA, Baldwin GE, Buntin J, Mansour A, Imran M, Papanikolaou D, Ziganshin BA, Elefteriades JA. Fate of preserved bicuspid valves at time of ascending aortic aneurysmectomy. Journal Of Cardiac Surgery 2019, 34: 318-322. PMID: 30900354, DOI: 10.1111/jocs.14024.Peer-Reviewed Original ResearchConceptsBicuspid aortic valveAortic valveAortic stenosisConcomitant bicuspid aortic valveAortic aneurysm surgeryAortic valve replacementAortic aneurysm patientsIntraoperative transesophageal echocardiographyAortic aneurysmectomyPostoperative echocardiogramsPreoperative echocardiogramValve replacementSingle surgeonAneurysm surgeryBicuspid valveTransesophageal echocardiographyAneurysm patientsSignificant abnormalitiesStudy groupValve functionPatientsSurgeryEchocardiogramStenosisAverage time
2018
Antithrombotic Therapy after Bioprosthetic Aortic Valve Replacement: A Therapeutic Morass
Gryaznov AA, Saeyeldin A, Abdelbaky M, Zafar MA, Tanweer M, Imran M, Papanikolaou D, Erben Y, Zefirova J, Ziganshin BA, Elefteriades JA. Antithrombotic Therapy after Bioprosthetic Aortic Valve Replacement: A Therapeutic Morass. Cardiology 2018, 140: 213-221. PMID: 30138919, DOI: 10.1159/000490924.Peer-Reviewed Original ResearchConceptsAortic valve replacementValve replacementAortic stenosisSurgical aortic valve replacementBioprosthetic aortic valve replacementCommon valvular disorderImpact of anticoagulationSymptomatic aortic stenosisHigh-risk patientsValvular heart diseaseCommon pathologic conditionsAntithrombotic therapyMultiple comorbiditiesPerioperative complicationsRemote complicationsSurgical managementEndovascular interventionHeart diseaseValvular disordersBiological valvesLower riskEuropean guidelinesPathologic conditionsComplicationsStenosis