2022
A machine learning approach for predicting complications in descending and thoracoabdominal aortic aneurysms
Ostberg NP, Zafar MA, Mukherjee SK, Ziganshin BA, Elefteriades JA. A machine learning approach for predicting complications in descending and thoracoabdominal aortic aneurysms. Journal Of Thoracic And Cardiovascular Surgery 2022, 166: 1011-1020.e3. PMID: 35120761, DOI: 10.1016/j.jtcvs.2021.12.045.Peer-Reviewed Original ResearchConceptsType B dissectionThoracoabdominal aortic aneurysmsB dissectionCause mortalityAortic aneurysmReceiver operator curveAortic diameterOperator curveInitial patient encounterOccurrence of dissectionSurgical intervention criteriaMean followPatient sexMyocardial infarctionPatient encountersRetrospective dataEnd pointPatientsAneurysmsDissectionMortalityRisk predictionComplicationsIntervention criteriaRupture
2020
Increased Virulence of Descending Thoracic and Thoracoabdominal Aortic Aneurysms in Women
Chen JF, Zafar MA, Wu J, Li Y, Rizzo JA, Papanikolaou D, Kalogerakos P, Abdelbaky M, Ellauzi H, Rohde S, Vinholo TF, Charilaou P, Buntin J, Mukherjee SK, Ziganshin BA, Elefteriades JA. Increased Virulence of Descending Thoracic and Thoracoabdominal Aortic Aneurysms in Women. The Annals Of Thoracic Surgery 2020, 112: 45-52. PMID: 33075319, DOI: 10.1016/j.athoracsur.2020.08.026.Peer-Reviewed Original ResearchConceptsThoracoabdominal aortic aneurysmsAortic deathFatal complicationAortic sizeAortic aneurysmFaster aneurysm growthMean aortic diameterComplication rateComposite endpointAortic diameterSurgical interventionCurrent guidelinesAneurysm sizeSex considerationsNatural historyAneurysm growthThoracicWomenDissectionYearly rateComplicationsDeathAneurysmsHigh rateSex differences
2019
Complex two-stage open surgical repair of an aortoesophageal fistula after thoracic endovascular aortic repair
Chaar C, Zafar MA, Velasquez C, Saeyeldin A, Elefteriades JA. Complex two-stage open surgical repair of an aortoesophageal fistula after thoracic endovascular aortic repair. Journal Of Vascular Surgery Cases And Innovative Techniques 2019, 5: 261-263. PMID: 31304437, PMCID: PMC6601018, DOI: 10.1016/j.jvscit.2019.02.011.Peer-Reviewed Original ResearchThoracic endovascular aortic repairEndovascular aortic repairAortoesophageal fistulaInfected endograftAortic repairExtra-anatomic aortic bypassOpen surgical repairOpen surgical approachFocus of infectionVisceral ischemia timesAortic bypassFatal complicationSurgical repairIschemia timeThoracic endograftSurgical approachThoracic aortaOptimal managementEndograftFistulaAortaClear guidelinesRepairComplex casesComplications
2018
Antithrombotic Therapy after Bioprosthetic Aortic Valve Replacement: A Therapeutic Morass
Gryaznov AA, Saeyeldin A, Abdelbaky M, Zafar MA, Tanweer M, Imran M, Papanikolaou D, Erben Y, Zefirova J, Ziganshin BA, Elefteriades JA. Antithrombotic Therapy after Bioprosthetic Aortic Valve Replacement: A Therapeutic Morass. Cardiology 2018, 140: 213-221. PMID: 30138919, DOI: 10.1159/000490924.Peer-Reviewed Original ResearchConceptsAortic valve replacementValve replacementAortic stenosisSurgical aortic valve replacementBioprosthetic aortic valve replacementCommon valvular disorderImpact of anticoagulationSymptomatic aortic stenosisHigh-risk patientsValvular heart diseaseCommon pathologic conditionsAntithrombotic therapyMultiple comorbiditiesPerioperative complicationsRemote complicationsSurgical managementEndovascular interventionHeart diseaseValvular disordersBiological valvesLower riskEuropean guidelinesPathologic conditionsComplicationsStenosisIntraoperative descending aortic dissection during aortic root replacement: successful management
Gryaznov AA, Ma WG, Erben Y, Zafar MA, Velasquez CA, Saeyeldin A, Ziganshin BA, Elefteriades JA. Intraoperative descending aortic dissection during aortic root replacement: successful management. Journal Of Thoracic Disease 2018, 10: 3065-3069. PMID: 29997974, PMCID: PMC6006070, DOI: 10.21037/jtd.2018.05.29.Peer-Reviewed Original ResearchIntraoperative aortic dissectionAortic dissectionSurgical cardiac interventionsAortic root replacementLife-threatening complicationsRoot replacementRare complicationCardiac interventionsOptimal managementSuccessful managementDissectionCatastrophic outcomesComplicationsHigh rateClear guidelinesMorbidityMortality
2017
Height alone, rather than body surface area, suffices for risk estimation in ascending aortic aneurysm
Zafar MA, Li Y, Rizzo JA, Charilaou P, Saeyeldin A, Velasquez CA, Mansour AM, Bin Mahmood SU, Ma WG, Brownstein AJ, Tranquilli M, Dumfarth J, Theodoropoulos P, Thombre K, Tanweer M, Erben Y, Peterss S, Ziganshin BA, Elefteriades JA. Height alone, rather than body surface area, suffices for risk estimation in ascending aortic aneurysm. Journal Of Thoracic And Cardiovascular Surgery 2017, 155: 1938-1950. PMID: 29395211, DOI: 10.1016/j.jtcvs.2017.10.140.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAortic Aneurysm, ThoracicBody HeightBody Surface AreaDatabases, FactualDecision Support TechniquesDisease ProgressionFemaleHumansMaleMiddle AgedPredictive Value of TestsProgression-Free SurvivalRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsYoung AdultConceptsAortic size indexBody surface areaAortic height indexAortic diameterAortic aneurysmYearly riskComplication-free survivalLong-term complicationsRisk of complicationsRisk estimationAortic dissectionComplication rateAortic sizeRisk stratificationComplicationsPredictive valueConcordance statisticInternational guidelinesNatural complicationsPatientsHeight indexSignificant predictorsAneurysmsTAAARiskNatural history of aortic root aneurysms in Marfan syndrome.
Saeyeldin A, Zafar MA, Velasquez CA, Ip K, Gryaznov A, Brownstein AJ, Li Y, Rizzo JA, Erben Y, Ziganshin BA, Elefteriades JA. Natural history of aortic root aneurysms in Marfan syndrome. Annals Of Cardiothoracic Surgery 2017, 6: 625-632. PMID: 29270374, PMCID: PMC5721101, DOI: 10.21037/acs.2017.11.10.Peer-Reviewed Original ResearchAortic root aneurysmAortic root diameterAortic dissectionRoot aneurysmMFS patientsAortic complicationsAdverse eventsAortic rootNatural historyRisk of complicationsAortic root dilatationMarfan syndrome patientsLogistic regression modelsAortic regurgitationCardiovascular complicationsHemodynamic roleDreadful complicationRoot dilatationAortic diameterLarge aneurysmsSyndrome patientsMarfan syndromeComplicationsPatientsAneurysms
2016
Early Spontaneous Resolution of an Iatrogenic Acute Type A Aortic Dissection
Zafar MA, Pang PYK, Henry GA, Ziganshin BA, Tranquilli M, Elefteriades JA. Early Spontaneous Resolution of an Iatrogenic Acute Type A Aortic Dissection. Aorta 2016, 04: 235-239. PMID: 28516101, PMCID: PMC5425262, DOI: 10.12945/j.aorta.2016.16.067.Peer-Reviewed Original ResearchAortic dissectionAcute Type A Aortic DissectionFollow-up computed tomography scanType A Aortic DissectionAnti-impulse therapyDeBakey type IA Aortic DissectionAcute aortic dissectionComputed tomography scanDevastating complicationCardiac catheterizationArch vesselsComplete resolutionElderly femalesTomography scanSpontaneous resolutionDissectionType IAngioplastyCatheterizationComplicationsPatientsAortaTherapyMonths