P148 Uncovering antibodies to cryptic epitopes: Use of flow cytometry crossmatch to differentiate between functional and denatured epitopes
Mangiola M, Lomago J, Marilyn M, Nichol L, Zern D, McGowan K, Sese D, Bow L, Zeevi A. P148 Uncovering antibodies to cryptic epitopes: Use of flow cytometry crossmatch to differentiate between functional and denatured epitopes. Human Immunology 2016, 77: 145. DOI: 10.1016/j.humimm.2016.07.213.Peer-Reviewed Original ResearchAntigen beadsCryptic epitopesFlow cytometry crossmatchSingle antigen beadsSmall bowel transplantHLA antibody detectionClass II profileBowel transplantCytometry crossmatchDR antigensHLA AbsDR7 allelesPatient beingCrossmatch requestsAntibody detectionSurrogate donorsMolecular typingFlow cytometryExon 2Ab profilesPotential targetPatient cellsEpitopesPatientsPremature stop codon