2025
Validation of the WIfI Classification in the Vascular Quality Initiative database
Alameddine D, Satam K, Slade M, Cardella J, Aboian E, Guzman R, Mills J, Chaar C. Validation of the WIfI Classification in the Vascular Quality Initiative database. Journal Of Vascular Surgery 2025 PMID: 40056961, DOI: 10.1016/j.jvs.2025.03.001.Peer-Reviewed Original ResearchChronic limb-threatening ischemiaWIfI stageWIfI scoreWIfI classificationLower extremity revascularizationPeripheral vascular interventionsMajor amputationAssociated with major amputationWIfI clinical stagePredicting major amputationPeripheral vascular interventional proceduresAssociated with increased riskVascular Quality InitiativeRegression analysisAmputation groupAmputation resultsCox regression analysisLimb-threatening ischemiaCharacteristics of patientsAfrican AmericansQuality InitiativeAmputationRisk factorsExtremity revascularizationFoot Infection classificationAntithrombotic Therapy In Patients With Atrial Fibrillation Undergoing Peripheral Vascular Interventions
Said S, Alameddine D, Aboian E, Strosberg D, Tonnessen B, Cardella J, Guzman R, Chaar C. Antithrombotic Therapy In Patients With Atrial Fibrillation Undergoing Peripheral Vascular Interventions. Annals Of Vascular Surgery 2025, 112: 436-437. DOI: 10.1016/j.avsg.2024.11.070.Peer-Reviewed Original Research
2024
Clinical Implications of Low Body Mass Index on Endovascular Lower Extremity Revascularization
Pinto Rodriguez P, Alameddine D, Huttler J, Damara F, Slade M, Cardella J, Guzman R, Chaar C. Clinical Implications of Low Body Mass Index on Endovascular Lower Extremity Revascularization. Annals Of Vascular Surgery 2024, 106: 350-359. PMID: 38810726, DOI: 10.1016/j.avsg.2024.02.031.Peer-Reviewed Original ResearchPeripheral vascular interventionsPeripheral arterial diseaseLower body mass indexUnderweight patientsLong-term outcomesBody mass indexNonobese patientsMass indexRetrospective analysis of patientsRate of thrombotic complicationsHigher 30-day mortalityRates of amputation-free survivalRate of reinterventionOutcomes of patientsPeripheral arterial disease patientsAnalysis of patientsKaplan-Meier analysisImpact of malnutritionBaseline demographic characteristicsChronic limb-threatening ischemiaEpidemic of obesityOptimization of nutritionLonger hospital lengthAdverse limb eventsAmputation-free survivalClinician perspectives regarding CYP2C19 genotype testing in patients with critical limb ischemia: A Delphi approach
Regan C, Scierka L, Dardik A, Tonnessen B, Chaar C, Ionescu C, Aboian E, Cardella J, Nassiri N, Guzman R, Attaran R, Nagpal S, Shah S, Smolderen K, Mena-Hurtado C. Clinician perspectives regarding CYP2C19 genotype testing in patients with critical limb ischemia: A Delphi approach. Vascular 2024, 33: 466-471. PMID: 38669051, DOI: 10.1177/17085381241246318.Peer-Reviewed Original ResearchDual antiplatelet therapyPeripheral arterial diseaseCYP2C19 testingCYP2C19 mutationsHeterogeneity of treatment effectsPeripheral vascular interventionsConsensus statementKnowledge questionsAntiplatelet therapyGenetic testingVascular surgeryAcademic health systemBarriers to implementationInterquartile rangeCYP2C19 genotype testingVascular diseaseInterventional cardiologyModified Delphi methodPatient's metabolic statusManagement of patientsCritical limb ischemiaPerceived barriersPeripheral vascular diseaseArterial vascular diseaseClinician perspectives
2023
The Utilization of Protamine during Peripheral Vascular Interventions in the VQI
Ali S, Shebl F, Aboian E, Strosberg D, Fischer U, Cardella J, Guzman R, Ochoa Chaar C. The Utilization of Protamine during Peripheral Vascular Interventions in the VQI. Annals Of Vascular Surgery 2023, 101: 72-79. PMID: 38110083, DOI: 10.1016/j.avsg.2023.10.019.Peer-Reviewed Original ResearchPeripheral vascular interventionsAdjusted rate ratiosProtamine useCardiac complicationsPropensity matchingVascular interventionsChronic obstructive pulmonary diseasePropensity scoreCharacteristics of patientsPeripheral arterial diseaseCongestive heart failureObstructive pulmonary diseaseMultivariable Poisson regressionUse of protamineSignificant differencesMedical comorbiditiesP2Y12 inhibitorsPerioperative bleedingPerioperative medicationsPerioperative outcomesDistal embolizationPatient comorbiditiesCarotid surgeryHeart failurePulmonary disease
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