2024
Liver resection versus radiofrequency ablation or trans-arterial chemoembolization for early-stage (BCLC A) oligo-nodular hepatocellular carcinoma: meta-analysis
Romano P, Busti M, Billato I, D’Amico F, Marchegiani G, Pelizzaro F, Vitale A, Cillo U. Liver resection versus radiofrequency ablation or trans-arterial chemoembolization for early-stage (BCLC A) oligo-nodular hepatocellular carcinoma: meta-analysis. BJS Open 2024, 8: zrad158. PMID: 38323881, PMCID: PMC10848305, DOI: 10.1093/bjsopen/zrad158.Peer-Reviewed Original ResearchConceptsBarcelona Clinic Liver CancerTrans-arterial chemoembolizationDisease-free survivalBarcelona Clinic Liver Cancer-A patientsBenefits of LRLiver resectionRadiofrequency ablationHepatocellular carcinomaOS benefitOverall survivalA patientsBarcelona Clinic Liver Cancer ABarcelona Clinic Liver Cancer stageDisease-free survival benefitRisk ratioOutcomes of LRMeta-analysisComparative cohort studyCase-control studyChina Biological Medicine DatabaseHCC patientsCohort studyPrimary outcomeNewcastle-OttawaQuality of studies
2012
Use of N‐acetylcysteine during liver procurement: A prospective randomized controlled study
D'Amico F, Vitale A, Piovan D, Bertacco A, Morales R, Frigo A, Bassi D, Bonsignore P, Gringeri E, Valmasoni M, Garbo G, Lodo E, D'Amico FE, Scopelliti M, Carraro A, Gambato M, Brolese A, Zanus G, Neri D, Cillo U. Use of N‐acetylcysteine during liver procurement: A prospective randomized controlled study. Liver Transplantation 2012, 19: 135-144. PMID: 22859317, DOI: 10.1002/lt.23527.Peer-Reviewed Original ResearchMeSH KeywordsAcetylcysteineAdolescentAdultAgedAntioxidantsChi-Square DistributionFemaleGraft SurvivalHumansInfusions, IntravenousItalyKaplan-Meier EstimateLiver TransplantationMaleMiddle AgedPortal VeinPrimary Graft DysfunctionProportional Hazards ModelsProspective StudiesSingle-Blind MethodTime FactorsTissue and Organ HarvestingTreatment OutcomeYoung AdultConceptsGraft survivalLiver transplantationNAC groupLiver procurementN-acetylcysteineControl groupSuboptimal graftsEffect of NACNAC protocolIschemia/reperfusion damageFirst liver transplantationEarly graft functionGraft survival ratesChronic liver diseaseSingle-blinded procedureGraft functionLT outcomesPostoperative complicationsPrimary endpointCox analysisNAC infusionRandomized studyLiver diseaseAdult candidatesPrimary dysfunction
2007
A New Experimental Model of Isolated Perfused Pig Liver to Support Acute Hepatic Failure
Carraro A, Gringeri E, Calabrese F, Violi P, Brolese A, Zanus G, Boccagni P, Valente M, Bassi D, D’Amico F, D’Amico D, Cillo U. A New Experimental Model of Isolated Perfused Pig Liver to Support Acute Hepatic Failure. Transplantation Proceedings 2007, 39: 2028-2030. PMID: 17692683, DOI: 10.1016/j.transproceed.2007.05.070.Peer-Reviewed Original ResearchConceptsPerfused liver modelIsolated porcine liverLiver transplantationLiver failureAwaiting transplantationOrgan procurement ratesHepatic functionEffective treatmentEx vivo perfused liver modelPortal bloodHemodynamic homeostasisIsolated liverPerfused pig liverLiverLiver supportRecipient pigsTransplantationPatientsIsolated perfused pig liverLiver modelProcurement ratesMetabolic capacity
2005
Role of blood AFP mRNA and tumor grade in the preoperative prognostic evaluation of patients with hepatocellular carcinoma
Cillo U, Vitale A, Navaglia F, Basso D, Montin U, Bassanello M, D'Amico F, Ciarleglio F, Brolese A, Zanus G, De Pascale V, Plebani M, D'Amico D. Role of blood AFP mRNA and tumor grade in the preoperative prognostic evaluation of patients with hepatocellular carcinoma. World Journal Of Gastroenterology 2005, 11: 6920-6925. PMID: 16437593, PMCID: PMC4717031, DOI: 10.3748/wjg.v11.i44.6920.Peer-Reviewed Original ResearchConceptsTumor gradeHepatocellular carcinomaRadical therapyAFP mRNASurgical therapyMRNA statusPrognostic evaluation of HCC patientsAssessment of tumor gradePrognostic evaluation of patientsDiagnosis of hepatocellular carcinomaNodule sizeDetermination of tumor gradeEvaluation of HCC patientsPreoperative tumor gradeMedian follow-upPercutaneous ablative proceduresTumor-related variablesSignificant survival predictorsPotential prognostic roleCohort of patientsEvaluation of patientsSignificant prognosticatorsPrognostic rolePercutaneous biopsyPerformance status
2003
Thermal homeostasis and liver transplantation.
D'Amico D, Vitale A, Cillo U, Boccagni P, Brolese A, Zanus G, Bassanello M, Montin U, Gringeri E, D'Amico F, Ciarleglio F, Cappuzzo G, Carraro A. Thermal homeostasis and liver transplantation. Acta BioMedica 2003, 74 Suppl 2: 30-3. PMID: 15055030.Peer-Reviewed Original ResearchConceptsGraft ischemia-reperfusion injuryGraft function recoveryPostoperative graft functionIschemia-reperfusion injuryInfluence of hypothermiaIntraoperative heat lossGraft functionLiver transplantationSevere hypothermiaCoagulation systemNormothermic oxygenated perfusionFunctional recoveryExtracorporeal circuitDonor poolAngiogenic mechanismsHypothermiaActive warmingOxygenated perfusionThermal homeostasisClinical researchGraftCardiovascular activityLiverDeleterious effectsHomeostasis