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Annual Research Day

Yale Plastic and Reconstructive Surgery has been hosting an annual Research Day since 1997. All residents from PGY2 to PGY6 are required to participate. Fellows and research fellows within the division are also encouraged to present their work. These presentations are intended to highlight some of the many ongoing projects on which the residents, fellows, and research fellows work throughout the year.


The Availability of Certified Cleft Care in the United States: A Geospatial Analysis of 1-Hour Access to Care
Arvind Gowda, Connor Peck, Yassmin Parsaei, Jakob Lattanzi, Jenny Yang, Joseph Lopez, Derek Steinbacher

Predictive Accuracy of Elevated Mitotic Rate on Lymph Node Positivity and Recurrence in Thin Melanomas
Catherine L. Ly, Ondrej Blaha, Wei Wei, Kelly Olino, Anjela Galan, Harriet Kluger, Stephan Ariyan, James E. Clune

Application of Induced Pluripotent Stem Cells and Mesenchymal Stem Cells to a Murine Model for Ischemic Wound Healing: A Pilot Study
Ho J, Dash BC, Chuang C, Dardik A, Hsia HC

3-D Printed Surgical Simulation for Metacarpal Fracture Fixation Improves Satisfaction, Confidence and Skill
Rajiv Iyengar, MD; Albert Woo, MD; Adnan Prsic, MD

Access to Pediatric Trauma Care in the United States
Jakob Lattanzi, Jenny Yang MD, Connor Peck MD, Sarah J Phillips MD, Derek Steinbacher MD, DMD, FACS

Outcomes of Free Flap Reconstructions of Pharyngectomy Defects for Head and Neck Cancer
Samuel Kim MD, Sacha C. Hauc BS, MPH, J Grant Thomson MD

Tranexamic Acid in Facial Feminization Surgery: Quantifying a High-Risk Setting
Alexandre Prassinos, Aaron Long, Adam Junn, Michael Alperovich

The Effect of Early Plastic Surgery Evaluation in Traumatic Lower Extremity Limb Salvage
Brogan G.A. Evans, MD, Tomer Avraham, MD

Botulinum Toxin-A for Hidradenitis Suppurativa: Development of a Randomized, Double blinded, Placebo-controlled Trial
Jeremy A. Goss, MD, Henry C. Hsia, MD, John A. Persing, MD

Trigger Finger Release in the United States: Trends in Operative Setting and Reimbursement
Vikram G. Mookerjee, MD, Alexander J. Kammien, BS, Adnan Prsic, MD, Jonathan N. Grauer, MD, David L. Colen, MD

Evaluating the Endpoint of Sentinel Lymph Node Biopsy in Melanoma Surgery
Thayer J. Mukherjee, Dr. Stephen Ariyan, Dr. James Clune

Resident Perceptions on Diversity in Plastic and Reconstructive Surgery in the United States
Lynn Zhao MD, Alexandra Junn AB, Catherine Ly MD and Adnan Prsic MD

Face Transplantation: Evaluating Impact, Donor Desirability and the Role for Genetic Engineering
Olivier F. Noel, MD, PhD, Bohdan Pomahac, MD

Crowdsourcing the Perception of the Bicoronal Scar in Open Cranial Vault Reconstruction
Tulsi Roy, Julia Chavez, David Cho , Rafal Sobota, and Russell R. Reid

The Effects of Lamination on Plaster Strength
Leah N. Herzog, MD, Rohan H. Kambeyanda, MD, J. Grant Thomson, MD, and Xuan Luo, MD

How Long Should We Hold our Splints? Assessment of Drying Time in Plaster
Rohan H. Kambeyanda, MD, Leah N. Herzog, MD, J. Grant Thomson, MD, Xuan Luo, MD

Management of Melanoma and Positive Margins
Martin J Carney MD, Sarah Islam BS, Katelyn Lewis BS, James Clune MD

Single Surgeon Review of Management of Fluid Collections in Post-operative Abdominal Wall Reconstruction Patients
John Collar, MD, Sara Islam, BS, J. Grant Thomson, MD

Multiplex Gene Expression Analysis Reveals Distinct Rejection Patterns in Skin and Mucosa of Facial Vascularized Composite Allotransplants
Martin Kauke-Navarro MD, William J. Crisler PhD, Christine G. Lian MD, Nathaniel S. Treister, DMD, George F. Murphy MD, Rachael A. Clark MD, PhD, Bohdan Pomahac, MD

Autologous Fat Grafting Promotes Sustained Release of IL-13 and TGF-Beta by Septal Cartilages to Cartilages to Limit Inflammation and Excessive Cartilage Resorption in Rhinoplasty
Kaiti Duan BS; Alvaro Reategui BA; Sarah Phillips BS; Arvind U. Gowda MD; Biraja Dash PhD; Joseph Lopez MD, MBA; Henry Hsia, MD; Derek M. Steinbacher MD, DMD

Influence of Health Policy on Payment and Regional Shifts in Gender Affirming Surgery
Sacha C. Hauc, MPH; Aaron S. Long, BS; Mohammad Ali Mozaffari, MD; Kirby Mateja, BS; Alicia P. Stephan BS; Adam Junn, BS; Jean C. Rivera, BS; Jacob Dinis, BS; Alexandra Junn, AB; Michael Alperovich MD, MSc

Human iPSC-Vascular Smooth Muscle Cell Spheroids Demonstrate Size-dependent Alterations in Cellular Properties and Secretory Function
Sara Islam, BS, Biraja Dash, PhD, Henry Hsia, MD

Manual and AI Radiographic Severity Assessment for Metopic Craniosynostosis: Is There an Association with Longterm Neurocognitive Outcomes?
Aaron S. Long, BS; Sacha C. Hauc, MPH; Mohammad Ali Mozaffari, MD; Adam H. Junn, BS; Jean Carlo Rivera, BS; Derek Steinbacher, MD, DMD; John A. Persing, MD; Michael Alperovich, MD, MSc

How Will Numeric Step 1 Scores be Compared to Pass/Fail Reports: Plastic Surgery Residency Program Director Perspectives on Upcoming Application Cycles
Rivera JC, Long AS, Juan HY, Hauc SC, Junn A, Persing J, Alperovich M.


Nodal Sampling in Auricular Melanoma: Is Preoperative Lymphoscintigram Necessary?
John Smetona, MD, Seth Noorbakhsh BA, Kelly Olino MD, Craig Moores MD, Sarah Weiss MD, Darko Pucar MD PhD, Stephan Ariyan MD MBA, James Clune MD

Applying the Concept of Dynamic External Fixation to the Mandible
David M. Tsai, MD

Primary Cleft Palate Repair Among Older-Age Children and Adolescents in the United States
Gowda AU, Peck CJ, , Khetpal S, Lopez J, Shultz BN, Parsaei Y, Wu RT, Steinbacher DM.

Re-evaluation of Mitotic Rate for Melanoma Staging
Catherine L. Ly, Ondrej Blaha, Wei Wei, Harriet Kluger, Stephen Ariyan, James E. Clune

Diversity in Academic Hand Surgery
Carolyn Chuang MD, Alexandra Junn AB, Alvaro Reátegui BA, J Grant Thomson MD FACS MSc

Hand Consult and Handipedia Survey: An Interdisciplinary Effort to Improve Resident Education
Rajiv J. Iyengar MD, J. Grant Thomson MD

Does Peri-operative TXA Reduce Post-Operative Edema in Orthognathic Surgery? A Three-Dimensional Morphometric Analysis.
Jenny F. Yang MD, Alvaro A. Reategui BA, Sarah J. Phillips BS, Connor J. Peck BS, Yassmin Parsaei DMD, Joseph Lopez MD, MBA, Derek M. Steinbacher DMD, MD, FACS

Sex, Race, Insurance, and Pain: Do Patient Sociodemographics Influence Post-Operative Opioid Prescriptions among Hand Surgeons?
Carney MJ, Peck CJ, Chiu A, Park KE, Prassinos A, Allam O, Thomson JG, Prsic A.

Socioeconomic Factors Predict Delayed Pediatric Hand Tendon Injuries
Samuel Kim MD, Michael Mercier BS, Adnan Prsic MD

Sociodemographic Disparities in Access to Secondary Cleft Rhinoplasty
Sarah Phillips, BS; Sacha C. Hauc, BS, BA, MPH; Sumun Khetpal, BS, BA; Daniel C. Sasson, BA; Alexandre Prassinos, MD; Joseph Lopez, MD, MBA; Derek M Steinbacher, MD, DMD, FACS

Lower Extremity Limb Salvage – A Plastic Surgery Intervention
Brogan Evans, MD, Tomer Avraham, MD

Management of Hidradenitis Suppurativa: A Retrospective Cohort Study
Jeremy A. Goss, MD, and John A. Persing, MD

Determining Morbidity of Adding Genioplasty to Bimaxillary Orthognathic Surgery
Vikram Mookerjee, Connor Peck, Alvaro Reategui, Joseph Lopez, Derek Steinbacher

The Role of Preoperative Antibiotics in Management of Distal Radius Fractures: A Retrospective Review
J. Scott Persing, M.D., M.P.H., Craig Moores M.D., Carrie R Swigart M.D., J. Grant Thomson, M.D., M.S.c

Geometrically Complex Midface Reconstruction Using 3-D Printed, Scaffolds Augmented with Autologous Stromal Vascular Fraction
Joseph Lopez, M.D. M.B.A.; Srujan Singh, B.S.; Ethan Nyberg, Ph.D.; Ashley Farris, B.S.; Derek M. Steinbacher, M.D. DMD; Warren Grayson, Ph.D.; Michael P. Grant M.D. Ph.D.

Impact of Insurance Payer and Socioeconomic Status on Type of Autologous Breast Reconstruction
Jacob Dinis B.S*, Alexandra Junn A.B*, Fouad Chouairi B.S, Michael Mercier B.A, Tomer Avraham M.D, Evan Matros M.D, MMSc, MPH, Michael Alperovich M.D, M.Sc

Fibronectin Functionalized Collagen Scaffold Preferentially Promotes Vascular Smooth Muscle Cell Proliferation and Promotes Stronger Vascular Formation via Alpha-v Beta-3 Integrin Interactions
Kaiti Duan, Daniel C Sasson, Biraja Dash, Henry Hsia MD

Challenges in Access to Care for Helmet Therapy in Treatment of Deformational Plagiocephaly Among Lower-Income and Medicaid-Insured Patients
Alexandra Junn, AB, Jacob Dinis, BS, Aaron Long, BS, Sacha Hauc, BS, MPH, Sarah Philips, BS, Joseph Lopez, MD, MBA, John A Persing, MD, Michael Alperovich, MD, MSc

Beauty in the Eye of the—Computer? The Feasibility of Using Commercial Artificial Intelligence Software in Aesthetic Craniofacial Research
Connor J. Peck, BS; Sumun Khetpal, BS; Yassmin Parsaei, DMD; Arvind Gowda, MD; Kaiti Duan,BS; Vishaben Patel, BA; Sarah Phillips, BS; Alvaro Reategui, BA; Navid Pourtaheri, MD PhD; Joseph Lopez, MD MBA; Derek Steinbacher MD DMD

Improving Nasal Symmetry with the Alar Composite Graft: Technique and Outcome Assessments in Cleft Patient
Sarah Phillips BS, Martin Carney MD, Yassmin Parsaei DMD, Chris Kalmar MD MPH, Joseph Lopez MD MBA, Derek M Steinbacher MD DMD FACS

Swelling Resolution Post-Triple Jaw Surgery: A 3D Analysis
Alvaro Reategui BA; Sarah Phillips BS; Jacob Dinis BS; Alexandra Junn BA; Yassmin Parsaei DMD; Jenny Yang MD; Joseph Lopez MD MBA; Derek Steinbacher DMD, MD

Tumor Necrosis Factor-alpha Increases Paracrine Expression and Survivability of Vascular Smooth Muscle Cells
Daniel C. Sasson, BA; Kaiti Duan, BS; Biraja C. Dash, PhD; Henry C. Hsia, MD


Safety of Compression Therapy for Venous Ulcer Disease in the setting of Congestive Heart Failure
J. Scott Persing, Robert Attaran, Amanda Cavanaugh, Cynthia Tsai, Tariq Ahmad, Cassius Ochoa-Chaar, Henry Hsia

The Expanded Use of the Subunit Method in Managing Giant Rhinophyma
Ean Saberski, Henry Hsia

Malignant Melanoma in the Elderly: Different Nurture or Different Nature?
John Smetona; Kelly Olino; Stephen Ariyan; James Clune

Designing a Self-Directed Microsurgery Practice Curriculum
David Tsai

Novel Technique for Dorsal Nasal Onlay Utilizing Crushed Septal Cartilage and Autologous Fat
Arvind Gowda, Navid Pourtaheri, Eric Park, Omar Allam, Seija Maniskas, Derek Steinbacher

The Effects of Post-Mastectomy Radiotherapy on Immediate Autologous Breast Reconstruction
Catherine Ly, Sumun Khetpal, Danielle R. Heller, Susan A. Higgins, Brigid Killelea, Michael Alperovich, Tomer Avraham

An Analysis of Negative Online Reviews of Augmentation Mastopexy
Carolyn Chuang, Henry Hsia

Analysis of Hand and Microsurgery Transfers to a Level I Trauma Center
Rajiv Iyengar, Marc Walker, Grant Thomson

Does Initial Unilateral Cleft Lip Width Predict Final Aesthetic Outcome?
Jenny Yang, John Smetona, A Hariharan, CJ Peck, Navid Pourtaheri, Derek Steinbacher

Safety of Wide Awake Endoscopic Carpal Tunnel Release Performed Under Local Anesthesia
Omar Allam, Martin Carney, Eric Park, Samuel Kim, Craig Moores, Grant Thomson, Adnan Prsic

MicroRNA Microarray Profiling in Infantile Hemangiomas
Samuel Kim, Yong Kong, Richard Antaya, Deepak Narayan

Not Just an Expression: Utilizing Single-cell Transcriptomics to Elucidate Wound Healing
Alexandre Prassinos, M. Teresa Sandoval-Schaefer, Michael Rutenberg Schoenberg, Michael Gazes, Stephen Vyce, Henry Hsia, Mark Gerstein, Valerie Horsley

BMP-2 Use for Alveolar Cleft Repair is Associated with Increased Incidence of Postoperative Nasal Stenosis
Jeremy Goss, Margie S. Hunter, Eric S. Armbrecht, Alexander Y. Lin

Peri-Operative Antibiotics and Wound Infection Rates of Volar Locking Plates for the Treatment of Closed Distal Radius Fractures
Craig Moores, Martin Carney, Grant Thomson

Intraarticular Injection of Autologous Fat: Effective Minimally Invasive Treatment for Temporomandibular Joint Disease
Navid Pourtaheri, Ludmila Chandler, Maham Ahmad, Seija Maniskas, Derek Steinbacher

Preliminary Data Report on Multiscale Pre-Vascularized Natural Bone and 3D-Printed Hyperelastic Bone for Skeletal Regeneration
Xiaona Lu, Edward Han, Hong Qian, Juan Wang, Yifan Yuan, Laura E. Niklason, Jacob V.P. Eswarakumar, Ramille Shah, Adam E. Jakus, Derek Steinbacher

A Craniomorphometric Comparison Analysis Distinguishing Unilateral Lambdoid Craniosynostosis From Deformational Plagiocephaly
Omar Allam, Eric Park, Navid Pourtaheri, Mohammad Ali Mozaffari, Sumun Khetpal, Ludmila Chandler, Maham Ahmad, John Smetona, John Persing, Michael Alperovich

Bio-Functional Collagen Matrix Scaffold Composition Differentially Promotes Paracrine Activity in Human Induced Pluripotent Stem Cell Derived Vascular Smooth Muscle Cells
Kaiti Duan, Biraja Dash, Henry Hsia

Calling for More Research, Education, and Innovation in Plastic Surgery: A Five- Year Analysis of Physician-Industry Payments Using the Open Payments Database
Sumun Khetpal, Elbert Mets, Maham Ahmad, Neil Pathak, John Persing, Michael Alperovich

Distinguishing Craniomorphometric Characteristics and Severity in Metopic Synostosis Patients
Eric Park, Ludmila Chandler, Omar Allam, Mohammad Ali Mozaffari, Sumun Khetpal, John Smetona, Navid Pourtaheri, Xiaona Lu, John Persing, Michael Alperovich


Prognostic Factors in Determining the Recurrence of Desmoplastic Melanoma
Sarah Persing, Raysa Cabrejo, Wael Ibrahim, Anjela Galan, Stephan Ariyan, James Clune

Comparative Outcomes of Cis- and Trans- Gender Patients Undergoing Primary Breast Augmentation
Kyle Gabrick, Fouad Chouairi, Roberto Travieso, John Persing, Michael Alperovich

An Evaluation of National Practices for the Surgical Treatment of Syndactyly
Fouad Chouairi, Michael Mercier, J. Scott Persing, Kyle S Gabrick, James Clune, Michael Alperovich

Nonlinear Fluid Dynamic Modeling is Predictive of Pulmonary Fat Embolus Risk in Gluteal Augmentation
Ean Saberski, J. Grant Thomson

The Effect of Intraoperative Temperature on Free Flap Thrombosis
John Smetona, Kyle Gabrick, Jacob Dinis, Fouad Chouairi, Michael Alperovich, J. Grant Thomson

Trigger Finger: Staging and Treatment Outcomes
David Tsai, Raysa Cabrejo, J. Grant Thomson

Improved Facial Symmetry with Treatment During Active Unilateral Condylar Hyperplasia
Seija Maniskas, Catherine Ly, Yassmin Parsaei, Karl C. Bruckman, Derek Steinbacher

Timing of Cleft Palate Repair: Insights from the Analysis of Two National Databases
Arvind Gowda, Connor J. Peck, Blake N. Shultz, Robin T. Wu, Derek Steinbacher

Long-Term Neurocognitive Outcomes in Sagittal Synostosis: The Impact of Reoperation
Carolyn Chuang, Tafadzwa L Chaunzwa, Robin Wu; Anusha Singh, Anup Patel, Jenny F Yang, Peter W. Hashim, Roberto Travieso, Jordan S. Terner, Linda C. Mayes, Charles C. Duncan, John A. Jane, Sr., John A. Jane, Jr., Kant Y. Lin, David J. Bridgett, John A. Persing

Conformity of 3D Surgical Plans with Actual Results: A Comparison of VSP Accuracy Between Five Different Craniofacial Procedures
Seija Maniskas, Xiaona Lu, Ludmila Chandler, Karl C. Bruckman, Jenny Yang, Derek Steinbacher

Radiographic Predictors of FACE-Q Outcomes Following Non-Operative Orbital Floor Fracture Management
Kyle Gabrick, John Smetona , Rajiv Iyengar, Jacob Dinis, Fouad Chouairi, Connor Peck, John A. Persing, Michael Alperovich

Concurrent High Condylectomy and Orthognathic Surgery for Treatment of Patients with Unilateral Condylar Hyperplasia
Seija Maniskas, Yassmin Parsaei, Karl C. Bruckman, Derek Steinbacher

Differential Pulley Release in Trigger Finger: A Prospective Randomized Clinical Trial
Marc Walker, Robin T. Wu, Peter Hetzler, Yuen-Jong Liu, Connor J. Peck, John Smetona, J. Grant Thomson

Safety of Immediate Autologous Breast Reconstruction in the Setting of PMRT
Danielle R. Heller, Haoran Zhuo, Nisha Parikh, Yawei Zhang, Yekaterina Polyatskaya, Michael Alperovich, Donald R. Lannin, Brigid Killelea, Tomer Avraham

Tapping the Regenerative Potentials of human iPSC-derived Smooth Muscle Cells to Promote Wound Healing
Biraja C. Dash, Ocean Setia, Hassan Peyvandi, Lara Lopes, James Nie, Jolanta Gorecka, Alan Dardik, Henry Hsia

The Effects of Immunotherapy on the Overall Survival of Subungual Melanoma Patients
Raysa Cabrejo, Sarah Persing, James Clune

Impact of Socioeconomic Status on Psychological Functioning in Survivorship Following Breast Cancer and Reconstruction
Nicole K. Le, Kyle S. Gabrick, Fouad K. Chouairi, Elbert J. Mets, Tomer Avraham, Michael Alperovich

Condyle Position, Condyle Morphology, and Temporomandibular Joint Space in Robin
Sequence Before and After Mandibular Distraction Osteogenesis Anusha Singh, Seija A. Maniskas, Alexander Sun, Alexander Wilson, Sumun Khetpal, Karl C. Bruckman, Cory M. Resnick, Derek M. Steinbacher

Microsurgery Educational Tool for Objective Skill Assessment: A Step-wise Approach to Microanastomosis
Jack Kanouzi, Rajendra Sawh-Martinez, David Tsai, Deepak Narayan, J. Grant Thomson


Does ACell and hyperbaric oxygen improve adipocyte survival in large volume fat grafting?
Sabrina Pavri, Samuel Kim, Kim Blenman, Jack Kanouzi, Cyril Gary, Amanda Norwich, Deepak Narayan

Acral Lentigenous Melanoma: Does Surgical Approach Matter?
Marc Walker, Alexander Sun, Kyle Gabrick, Jack Kanouzi, YC Lo, A. Galen, James Clune, Deepak Narayan, Stephan Ariyan, Dale Han

Outcomes in subpectoral versus prepectoral implant-based reconstruction with fat grafting
Sarah Persing, Robin Wu, Catherine Sinnott, Mary Pronovost, Anke Ott-Young

Socioeconomic Disparities Impair Outcomes in Cleft Palate Repair
Roberto Travieso, Robin T. Wu, Connor J. Peck, Blake N. Schultz, Derek Steinbacher

Opponensplasty: A Biomechanical Study Quantifying Work of Thumb Opposition
Nickolay P. Markov, Kyle Steven Gabrick, Justin T. Zelones, Fioleda Prifti, J. Scott Persing, Michael Matthew

Fourier Analysis of Pulse Oximetry Waveform Data Detects Venous and Arterial Insufficiency in a Porcine Free Tissue Transfer Model
Ean Saberski, Kirk Shelley, J. Grant Thomson

To Operate or not to operate: a FACE-Q analysis of the psychosocial impact of orbital blowout fractures
Kyle Gabrick, John Smetona, Connor Peck, John A. Persing, Michael Alperovich

Head & Neck Reconstructive Microsurgery: Analysis of Publication Trends Among Specialties
David M. Tsai, Robin Wu, Michael Alperovich

Lymphedema Development Following Breast Conserving Therapy Arvind Gowda, James Nie, Elbert Mets, Tomer Avraham

fMRI reveals abnormal emotional regulation in nonsyndromic craniosynostosis
Jenny F. Yang, Robin T. Wu, Eric Brooks, Cheryl Lacadie, William Zucconi, Matthew Swallow, Jeffrey Eilbott, Alexander Sun, Carolyn Chuang, Raysa Cabrejo, Derek M. Steinbacher, Kevin Pelphrey, John A. Persing

Steroid Injection in Carpal Tunnel Syndrome: A Critical Analysis
Yuen-Jong Liu, Robin Wu, J. Grant Thomson

Analysis of Nasolabial Anatomy in Unilateral Cleft Lip Patients
Rajendra Sawh-Martinez, Joseph Zeidan, Derek Steinbacher

Functional Network Development in Sagittal Craniosynostosis Treated with Whole Vault Cranioplasty
Raysa Cabrejo, Cheryl Lacadie, Alexander Sun, Carolyn Chuang, Jenny Yang, Eric Brooks, Joel Beckett, Kyle Gabrick, Derek Steinbacher, Michael Alperovich, Kevin Pelphrey, Todd Constable, John Persing

Outcomes in Academic and Community Based Plastic Surgery Practices
Kyle Gabrick, Fouad Chouairi, M. Reinhart, Tomer Avraham, Michael Alperovich

The Temporal Relationship of Cranial Base Development and Facial Malformation in Apert’s and Crouzon’s Syndrome
Xiaona Lu, Antonio Jorge Forte, Rajendra Sawh-Martinez, Robin Wu, Cabrejo Raysa, Renato da Silva Freitas, Derek M. Steinbacher, Michael Alperovich, Nivaldo Alonso, John A. Persing

Prelamination of Vascularized Fascia Lata for Complex Abdominal Reconstruction
Amanda Norwich, Deepak Narayan, Gauri Pense, Samuel Kim

Genetic and Neurologic Characterizations of Craniosynostosis: Can We Predict Long Term Neurocognitive Outcomes?
Robin T. Wu, Andrew Timberlake, Paul Abraham, James Nie, Jenny Yang, Taylor Halligan, Alexander Sun, Carolyn Chuang, Michael Alperovich, Derek Steinbacher, John Persing