2024
Surgical management of rare tumors (Part 1)
Stetson A, Saluja S, Cameron D, Mansfield S, Polites S, Honeyman J, Dahl J, Austin M, Aldrink J, Christison‐Lagay E. Surgical management of rare tumors (Part 1). Pediatric Blood & Cancer 2024, e31287. PMID: 39185712, DOI: 10.1002/pbc.31287.Peer-Reviewed Original ResearchSynoptic operative reports for pediatric surgical oncology
Baertschiger R, Polites S, Fusco J, Roach J, Christison‐Lagay E, Malek M, Gow K. Synoptic operative reports for pediatric surgical oncology. Pediatric Blood & Cancer 2024, e31280. PMID: 39152638, DOI: 10.1002/pbc.31280.Peer-Reviewed Original ResearchImprove patient care outcomesElectronic medical record systemMultidisciplinary healthcare teamPatient care outcomesSurgical oncologySynoptic operative reportMedical record systemCare outcomesHealthcare teamPediatric surgical oncologyQuality assurance effortsDocumentation practicesData extractionDocumentation of surgical proceduresEffective communicationSynoptic reportingOperative notesRecording systemAssurance effortsEnhanced accessOncologyTumor characteristicsOperative reportsPediatric patientsResearch purposesEvaluation and Management of Biliary Dyskinesia in Children and Adolescents: A Systematic Review from the APSA Outcomes and Evidence-Based Committee
Kulaylat A, Lucas D, Chang H, Derderian S, Beres A, Ham P, Huerta C, Sulkowski J, Wakeman D, Englum B, Gulack B, Acker S, Gonzalez K, Levene T, Christison-Lagay E, Mansfield S, Yousef Y, Pennell C, Russell K, Rentea R, Tashiro J, Diesen D, Alemayehu H, Ricca R, Kelley-Quon L, Rialon K. Evaluation and Management of Biliary Dyskinesia in Children and Adolescents: A Systematic Review from the APSA Outcomes and Evidence-Based Committee. Journal Of Pediatric Surgery 2024 DOI: 10.1016/j.jpedsurg.2024.08.018.Peer-Reviewed Original ResearchSystematic reviewBiliary dyskinesiaOxford Levels of EvidencePreferred Reporting ItemsGrading of RecommendationsAmerican Pediatric Surgical Association OutcomesRisk of biasEvidence-based recommendationsDiagnostic criteriaPredictors of symptom reliefLevel of evidenceNon-operative managementResolution of symptomsPediatric-specific guidelinesOutcome of medical managementLong-term outcomesReporting ItemsNon-randomized studiesOxford LevelsMeta-analysesMethodological IndexAssociated outcomesClinical entityProspective studySymptom reliefCurrent surgical practice for central venous access to deliver chemotherapy and enteral access for nutritional support in pediatric patients with an oncological diagnosis
van den Bosch C, Grant C, Brown E, Morrison Z, Luques L, Christison‐Lagay E, Baertschiger R. Current surgical practice for central venous access to deliver chemotherapy and enteral access for nutritional support in pediatric patients with an oncological diagnosis. Pediatric Blood & Cancer 2024, e31206. PMID: 39030929, DOI: 10.1002/pbc.31206.Peer-Reviewed Original ResearchCentral venous catheterCentral venous accessPediatric patientsEnteral accessVenous accessNutritional supportTunneled central venous cathetersParenteral nutrition deliveryAdministration of chemotherapyLong-term outcomesCurrent surgical practiceDeterminants of outcomeSurgical oncology patientsModern oncology practiceCentral venous catheter managementDeliver chemotherapyVenous cathetersNutrition deliveryNutritional assessmentAccess surgerySurgical perspectiveOncological diagnosisOncology patientsNutritional statusSurgical practiceImplementing Screening, Brief Interventions, and Referral to Treatment at Pediatric Trauma Centers: A Step Wedge Cluster Randomized Trial
Mello M, Baird J, Spirito A, Lee L, Kiragu A, Scott K, Zonfrillo M, Christison-Lagay E, Bromberg J, Ruest S, Pruitt C, Lawson K, Nasr I, Aidlen J, Maxson R, Becker S. Implementing Screening, Brief Interventions, and Referral to Treatment at Pediatric Trauma Centers: A Step Wedge Cluster Randomized Trial. Journal Of Pediatric Surgery 2024 PMID: 39097494, DOI: 10.1016/j.jpedsurg.2024.07.003.Peer-Reviewed Original ResearchPediatric trauma centerElectronic health recordsReferral to treatmentBrief interventionTrauma centerImplementation strategiesPost-implementationAmerican College of Surgeons criteriaPrimary care providersCluster randomized trialStepped wedge cluster randomized trialCluster randomized designHigh-risk useTrauma patientsDeliver SBIRTLevel of Evidence Level IIAdolescent trauma patientsCare providersImplementation trialImplementing screeningAOD screeningHealth recordsSpecialty servicesPre-implementationEHR dataScreening and Prophylaxis for Venous Thromboembolism in Pediatric Surgery: A Systematic Review
Kelley-Quon L, Acker S, St Peter S, Goldin A, Yousef Y, Ricca R, Mansfield S, Sulkowski J, Huerta C, Lucas D, Rialon K, Christison-Lagay E, Ham P, Rentea R, Beres A, Kulaylat A, Chang H, Polites S, Diesen D, Gonzalez K, Wakeman D, Baird R. Screening and Prophylaxis for Venous Thromboembolism in Pediatric Surgery: A Systematic Review. Journal Of Pediatric Surgery 2024, 161585. PMID: 38964986, DOI: 10.1016/j.jpedsurg.2024.05.015.Peer-Reviewed Original ResearchIncidence of venous thromboembolismVenous thromboembolismPharmacological prophylaxisSystematic reviewUltrasound screeningEpidemiology of venous thromboembolismAmerican Pediatric Surgical Association OutcomesPreferred Reporting ItemsStudy systematically reviewsLow-molecular-weight heparinRoutine ultrasound screeningCongenital heart diseasePediatric trauma populationPediatric surgical populationBody mass indexPediatric surgical patientsMolecular weight heparinSequential compression devicesInjury Severity ScoreCentral line placementSpinal cord injuryInflammatory bowel diseaseWeb of Science databasesLength of stayReporting ItemsClassification and Surgical Management of Anorectal Malformations: A Systematic Review and Evidence-Based Guideline from the APSA Outcomes and Evidence-Based Practice Committee
Smith C, Rialon K, Kawaguchi A, Dellinger M, Goldin A, Acker S, Kulaylat A, Chang H, Russell K, Wakeman D, Derderian S, Englum B, Polites S, Lucas D, Ricca R, Levene T, Sulkowski J, Kelley-Quon L, Tashiro J, Christison-Lagay E, Mansfield S, Beres A, Huerta C, Ham P, Yousef Y, Rentea R, Committee T. Classification and Surgical Management of Anorectal Malformations: A Systematic Review and Evidence-Based Guideline from the APSA Outcomes and Evidence-Based Practice Committee. Journal Of Pediatric Surgery 2024, 161598. PMID: 38997855, DOI: 10.1016/j.jpedsurg.2024.06.007.Peer-Reviewed Original ResearchSystematic reviewAnorectal malformationsEvidence-based best practicesSurgical managementConsensus-based questionsComprehensive search strategyPreferred Reporting ItemsComplex patient populationLevel of evidenceAmerican Pediatric Surgical Association OutcomesImprove careDiagnosis of anorectal malformationsGroup of anorectal malformationsTiming of surgical managementManagement of anorectal malformationsReporting ItemsLate repair groupMethod of fecal diversionTreatment of neonatesSurgical careOptimal surgical approachRate of prolapseMulti-institutional registryManagement of childrenSurgical management of anorectal malformationsManagement and Outcomes of Pediatric Lymphatic Malformations: A Systematic Review from the APSA Outcomes and Evidence-Based Practice Committee
Huerta C, Beres A, Englum B, Gonzalez K, Levene T, Wakeman D, Yousef Y, Gulack B, Chang H, Christison-Lagay E, Ham P, Mansfield S, Kulaylat A, Lucas D, Rentea R, Pennell C, Sulkowski J, Russell K, Ricca R, Kelley-Quon L, Tashiro J, Rialon K, Committee T. Management and Outcomes of Pediatric Lymphatic Malformations: A Systematic Review from the APSA Outcomes and Evidence-Based Practice Committee. Journal Of Pediatric Surgery 2024, 161589. PMID: 38914511, DOI: 10.1016/j.jpedsurg.2024.05.019.Peer-Reviewed Original ResearchSystematic reviewLymphatic malformationsConsensus statement of recommendationsPreferred Reporting ItemsEvidence-based recommendationsMedical therapyStatements of recommendationsLevel of Evidence 4Reporting ItemsModerate qualityPediatric lymphatic malformationsMulti-modality treatmentType of LMExtraction of dataConsensus statementOptimal individualized treatmentMacrocystic lesionsComplete responsePercutaneous treatmentMultidisciplinary approachSurgeryMalformationsOutcomesPatientsIndividualized treatmentA Unique Presentation of Nodular Masses in Infancy.
Velagala S, Heiden E, Lisse S, Wu H, Prior D, Chen G, Christison-Lagay E, Provini L, Antaya R, Spencer-Manzon M, Johnston L. A Unique Presentation of Nodular Masses in Infancy. NeoReviews 2024, 25: e370-e374. PMID: 38821908, DOI: 10.1542/neo.25-6-e370.Peer-Reviewed Original ResearchCentral Venous Catheter Consideration in Pediatric Oncology: A Systematic Review and Meta-analysis From the American Pediatric Surgical Association Cancer Committee
Christison-Lagay E, Brown E, Bruny J, Funaro M, Glick R, Dasgupta R, Grant C, Engwall-Gill A, Lautz T, Rothstein D, Walther A, Ehrlich P, Aldrink J, Rodeberg D, Baertschiger R. Central Venous Catheter Consideration in Pediatric Oncology: A Systematic Review and Meta-analysis From the American Pediatric Surgical Association Cancer Committee. Journal Of Pediatric Surgery 2024, 59: 1427-1443. PMID: 38637207, DOI: 10.1016/j.jpedsurg.2024.03.047.Peer-Reviewed Original ResearchCentral venous catheterIncreased risk of complicationsAbsolute neutrophil countRisk of complicationsIncreased riskCatheter placementCatheter compositionIncreased risk of hematomaTunneled central venous cathetersPlatelet count <Risk of hematomaMeta-analysisIncidence of complicationsLimited evidenceModern oncology practiceEnglish-language articlesCatheter salvageLock therapyNeutropenic patientsCatheter removalBloodstream infectionsTunneled cathetersPlatelet countNo significant differenceVenous cathetersMolecular Genetics Augment Cytopathologic Evaluation and Surgical Planning of Pediatric Thyroid Nodules
Spaulding S, Maayah M, Dinauer C, Prasad M, Darbinyan A, Morotti R, Christison-Lagay E. Molecular Genetics Augment Cytopathologic Evaluation and Surgical Planning of Pediatric Thyroid Nodules. Journal Of Pediatric Surgery 2024, 59: 975-980. PMID: 38246817, DOI: 10.1016/j.jpedsurg.2024.01.001.Peer-Reviewed Original ResearchFine-needle aspiration biopsyPediatric thyroid nodulesMolecular genetic testingBethesda IV nodulesPrediction of malignancyDICER1 mutationsThyroid nodulesGenetic testingNRAS mutationsMethods Retrospective chart reviewRetrospective chart reviewTime of surgeryBRAF V600E testingMutations/fusionsBethesda III nodulesChart reviewSurgical resectionFinal histopathologyThyroid resectionPediatric dataHistologic classificationSurgical specimensBRAF mutationsAspiration biopsyCytopathologic evaluationAdolescents’ Perceptions of Screening, Brief Intervention, and Referral to Treatment Service at Pediatric Trauma Centers
Mello M, Baird J, Spirito A, Scott K, Zonfrillo M, Lee L, Kiragu A, Christison-Lagay E, Bromberg J, Ruest S, Pruitt C, Lawson K, Nasr I, Aidlen J, Maxson R, Becker S. Adolescents’ Perceptions of Screening, Brief Intervention, and Referral to Treatment Service at Pediatric Trauma Centers. Substance Use Research And Treatment 2024, 18: 29768357241272356. PMID: 39175910, PMCID: PMC11339738, DOI: 10.1177/29768357241272356.Peer-Reviewed Original Research
2023
Children's Oncology Group's 2023 blueprint for research: Surgery
Gow K, Lautz T, Malek M, Cost N, Newman E, Dasgupta R, Christison‐Lagay E, Tiao G, Davidoff A, Committee T. Children's Oncology Group's 2023 blueprint for research: Surgery. Pediatric Blood & Cancer 2023, 71: e30766. PMID: 37950538, PMCID: PMC10872730, DOI: 10.1002/pbc.30766.Peer-Reviewed Original ResearchCounseling for opioids prescribed at discharge of hospitalized adolescent trauma patients
Mello M, Lee L, Christison-Lagay E, Spirito A, Becker S, Bromberg J, Ruest S, Zonfrillo M, Scott K, Pruitt C, Lawson K, Nasr I, Aidlen J, Baird J. Counseling for opioids prescribed at discharge of hospitalized adolescent trauma patients. Injury Epidemiology 2023, 10: 53. PMID: 37872639, PMCID: PMC10594678, DOI: 10.1186/s40621-023-00465-2.Peer-Reviewed Original ResearchAdolescent trauma patientsElectronic health recordsTrauma patientsPain medicationHospital dischargeAdolescent patientsAOD useDocumentation of counselingPrescribed pain medicationPediatric trauma centerPrescription pain medicationOpioid use disorderScreening resultsSafe useHospital discussionPrescribed opioidsTrauma centerNational cohortSafety counselingOpioidsHigh riskPatientsUse disordersDrug useAdolescent SurveyCritical elements of pediatric neuroblastoma surgery
Shaffiey S, Le H, Christison-Lagay E, Fialkowski E, Aldrink J, Grant C, Honeyman J, Janek K, Madonna M, Rhee D, Nuchtern J, Newman E, LaQuaglia M, Davidoff A, Shamberger R, Malek M. Critical elements of pediatric neuroblastoma surgery. Seminars In Pediatric Surgery 2023, 32: 151338. PMID: 38042090, DOI: 10.1016/j.sempedsurg.2023.151338.Peer-Reviewed Original ResearchConceptsHigh-risk neuroblastomaOncology GroupChildren's Oncology GroupPediatric surgical oncologyLong-term survivalNeuroblastoma surgeryExtracranial malignanciesEffective surgeryPediatric oncologyChildhood cancerSurgical oncologyNeuroblastomaSurgeryInternational SocietyOncologyExpert opinionLiterature reviewPatientsMalignancyCancerIncidenceImportant roleRare tumors: Opportunities and challenges from the Children’s Oncology Group perspective
Schultz K, Chintagumpala M, Piao J, Chen K, Shah R, Gartrell R, Christison-Lagay E, Pashnakar F, Berry J, O'Neill A, Vasta L, Flynn A, Mitchell S, Seynnaeve B, Rosenblum J, Potter S, Kamihara J, Rodriguez-Galindo C, Hawkins D, Laetsch T. Rare tumors: Opportunities and challenges from the Children’s Oncology Group perspective. 2023, 2: 100024. PMID: 37829670, PMCID: PMC10566015, DOI: 10.1016/j.ejcped.2023.100024.Peer-Reviewed Original ResearchTumor CommitteeStromal tumorsDesmoplastic small round cell tumorSmall round cell tumorGastrointestinal stromal tumorsNonmelanoma skin cancerRound cell tumorGonadal stromal tumorPleuropulmonary blastomaRare tumorAdrenocortical carcinomaNeuroendocrine tumorsCell tumorsRare cancersChildhood cancerColorectal carcinomaPancreatic tumorsNasopharyngeal carcinomaThyroid carcinomaHigh-quality researchCarcinomaSkin cancerTumorsYoung adultsCancerChildren's Oncology Group's 2023 blueprint for research: Rare tumors
Schultz K, Chintagumpala M, Piao J, Chen K, Gartrell R, Christison‐Lagay E, Berry J, Shah R, Laetsch T, Committee T. Children's Oncology Group's 2023 blueprint for research: Rare tumors. Pediatric Blood & Cancer 2023, 70: e30574. PMID: 37458616, PMCID: PMC10529839, DOI: 10.1002/pbc.30574.Peer-Reviewed Original ResearchImplications of Immunotherapy for Pediatric Malignancies: A Summary from the APSA Cancer Committee
Talbot L, Lautz T, Aldrink J, Ehrlich P, Dasgupta R, Mattei P, Tracy E, Glick R, Grant C, Brown E, Christison-Lagay E, Rodeberg D. Implications of Immunotherapy for Pediatric Malignancies: A Summary from the APSA Cancer Committee. Journal Of Pediatric Surgery 2023, 58: 2119-2127. PMID: 37550134, DOI: 10.1016/j.jpedsurg.2023.07.001.Peer-Reviewed Original ResearchAPSA Cancer CommitteeClass of immunotherapyT-cell therapyCancer CommitteePediatric malignanciesChimeric antigen receptor T-cell therapyMonoclonal antibody checkpoint inhibitorsTransgenic T cell receptorBispecific T-cell engagersCell therapyEarly phase clinical trialsYoung adultsConventional chemotherapeutic regimensDisease-related deathT-cell engagersClass of therapyT cell receptorCare of childrenCheckpoint inhibitorsAdverse eventsMetastatic diseaseSystemic treatmentChemotherapeutic regimensSurgical interventionClinical trialsVulvovaginal Complaints as the First Manifestation of Crohn's Disease in Children: Case Report
Brioso X, Banks D, Christison-Lagay E, Phatak U, Vash-Margita A. Vulvovaginal Complaints as the First Manifestation of Crohn's Disease in Children: Case Report. Journal Of Pediatric And Adolescent Gynecology 2023, 36: 494-496. PMID: 37196754, DOI: 10.1016/j.jpag.2023.05.007.Peer-Reviewed Original ResearchConceptsCrohn's diseasePediatric gynecologistImprovement of symptomsGastrointestinal inflammatory conditionsChronic constipationPrompt diagnosisPediatric populationVulvar irritationPremenarchal femalesVulvar complaintsCase reportInflammatory conditionsFirst manifestationVulvovaginal complaintsClear diagnosisHigh indexDiseaseDiagnosisFirst signAnatomical changesGynecologistsComplaintsTreatmentChildrenPoor growthLymphatic Malformations
Goss J, Zamakhshary M, Langer J, Christison-Lagay E. Lymphatic Malformations. 2023, 609-623. DOI: 10.1007/978-3-030-81488-5_47.ChaptersLymphatic malformationsCongenital vascular lesionsFoundation of careEmbryologic errorsSurgical therapySystemic therapyTreatment consensusInfiltrative patternVascular lesionsInvasive lesionsNovel agentsComplex lesionsPsychosocial distressMultidisciplinary teamIndividual lesionsRisk profileLesionsVital structuresLocalized massesTherapyMalformationsLarge groupMorbiditySclerotherapyLymphorrhea