2018
Management of Patients With Coronary Artery Malperfusion Secondary to Type A Aortic Dissection
Kreibich M, Bavaria JE, Branchetti E, Brown CR, Chen Z, Khurshan F, Siki M, Vallabhajosyula P, Szeto WY, Desai ND. Management of Patients With Coronary Artery Malperfusion Secondary to Type A Aortic Dissection. The Annals Of Thoracic Surgery 2018, 107: 1174-1180. PMID: 30444990, DOI: 10.1016/j.athoracsur.2018.09.065.Peer-Reviewed Original ResearchMeSH KeywordsAgedAortic Aneurysm, ThoracicAortic DissectionBlood Vessel Prosthesis ImplantationCohort StudiesCoronary Artery BypassCoronary Artery DiseaseCoronary CirculationFemaleGermanyHeart Arrest, InducedHospital MortalityHospitals, UniversityHumansKaplan-Meier EstimateLength of StayMaleMiddle AgedPostoperative ComplicationsPrognosisRetrospective StudiesRisk AssessmentStatistics, NonparametricSurvival AnalysisTreatment OutcomeConceptsCoronary artery malperfusionType B patientsType C patientsAntegrade cardioplegiaC patientsB patientsAortic dissectionCoronary ostiumDissection flapCA diseaseA Aortic DissectionType C lesionsManagement of patientsType B lesionsLong-term survivalCA bypassBypass GraftingPerioperative mortalityC lesionsComplete avulsionB lesionsLandmark analysisMalperfusionSuture repairPatientsPredictors of Recurrent Aortic Insufficiency in Type I Bicuspid Aortic Valve Repair
Habertheuer A, Milewski RK, Bavaria JE, Siki M, Freas M, Desai N, Szeto W, Ram C, Hu R, Vallabhajosyula P. Predictors of Recurrent Aortic Insufficiency in Type I Bicuspid Aortic Valve Repair. The Annals Of Thoracic Surgery 2018, 106: 1316-1324. PMID: 30055138, DOI: 10.1016/j.athoracsur.2018.06.026.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAdultAgedAortic ValveAortic Valve InsufficiencyBicuspid Aortic Valve DiseaseCardiac Valve AnnuloplastyDatabases, FactualFemaleFollow-Up StudiesHeart Valve DiseasesHeart Valve ProsthesisHumansLogistic ModelsMaleMiddle AgedPredictive Value of TestsRecurrenceReoperationRetrospective StudiesRisk AssessmentSurvival RateTreatment OutcomeOutcome After Operation for Aortic Dissection Type A in Morbidly Obese Patients
Kreibich M, Rylski B, Bavaria JE, Branchetti E, Dohle D, Moeller P, Vallabhajosyula P, Szeto WY, Desai ND. Outcome After Operation for Aortic Dissection Type A in Morbidly Obese Patients. The Annals Of Thoracic Surgery 2018, 106: 491-497. PMID: 29673638, DOI: 10.1016/j.athoracsur.2018.03.035.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAortic AneurysmAortic DissectionBody Mass IndexBody WeightCohort StudiesComorbidityFemaleHospital MortalityHumansLogistic ModelsMaleMiddle AgedObesity, MorbidOdds RatioPostoperative ComplicationsPrognosisReference ValuesRetrospective StudiesRisk AssessmentSurvival AnalysisTreatment OutcomeConceptsAortic dissection type AMorbidly obese patientsNormal weight patientsObese patientsSurgical repairWeight patientsDistal aortic repairImmediate surgical approachMore obese patientsCalculated blood volumeBody mass indexIntensive care unitLength of stayType AHospital mortalityHospital stayPostoperative complicationsAortic repairPostoperative outcomesCare unitClinical featuresClinical presentationMass indexNormal weightAdverse outcomesPredicting Distal Aortic Remodeling After Endovascular Repair for Chronic DeBakey III Aortic Dissection
Sultan I, Siki MA, Bavaria JE, Dibble TR, Savino DC, Kilic A, Szeto W, Vallabhajosyula P, Fairman RM, Jackson BM, Wang GJ, Desai ND. Predicting Distal Aortic Remodeling After Endovascular Repair for Chronic DeBakey III Aortic Dissection. The Annals Of Thoracic Surgery 2018, 105: 1691-1696. PMID: 29391144, DOI: 10.1016/j.athoracsur.2018.01.006.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAortic Aneurysm, ThoracicAortic DissectionBlood Vessel Prosthesis ImplantationChronic DiseaseCohort StudiesComputed Tomography AngiographyFemaleHospitals, UniversityHumansImaging, Three-DimensionalLogistic ModelsMaleMiddle AgedMultivariate AnalysisPredictive Value of TestsPrognosisRetrospective StudiesRisk AssessmentSeverity of Illness IndexSex FactorsSurvival RateTreatment OutcomeConceptsDeBakey III aortic dissectionAortic remodelingAortic dissectionVisceral vesselsTotal thrombosisGreater curveExact testDistal aortic remodelingOpen aortic reconstructionPositive aortic remodelingMultivariable logistic regressionNegative predictorFisher's exact testMultivariate logistic modelTomography angiography scansWilcoxon rank sumEndovascular aortic graftingAortic centersChronic dissectionAortic reconstructionCeliac axisAortic graftingEndovascular repairPrimary tearAortic size
2017
Conscious Sedation Versus General Anesthesia for Transcatheter Aortic Valve Replacement
Hyman MC, Vemulapalli S, Szeto WY, Stebbins A, Patel PA, Matsouaka RA, Herrmann HC, Anwaruddin S, Kobayashi T, Desai ND, Vallabhajosyula P, McCarthy FH, Li R, Bavaria JE, Giri J. Conscious Sedation Versus General Anesthesia for Transcatheter Aortic Valve Replacement. Circulation 2017, 136: 2132-2140. PMID: 28864443, DOI: 10.1161/circulationaha.116.026656.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnesthesia, GeneralAortic Valve StenosisComparative Effectiveness ResearchConscious SedationFemaleHospital MortalityHumansIntention to Treat AnalysisLength of StayMalePatient DischargePractice Patterns, Physicians'RegistriesRisk AssessmentRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsTranscatheter aortic valve replacementAortic valve replacementConscious sedationIntensive care unitGeneral anesthesiaHospital lengthValve replacementProcedural successCare unitEnd-point analysisPercutaneous transfemoral transcatheter aortic valve replacementConscious Sedation Versus General AnesthesiaTransfemoral transcatheter aortic valve replacementCardiology Transcatheter Valve Therapy RegistryThoracic Surgeons/American CollegeDeath/stroke ratePacemaker/defibrillator implantationTranscatheter Valve Therapy RegistryInverse probabilityConscious sedation groupDeath/strokeTreatment-weighted adjustmentTreatment-weighted analysisLower procedural successComparative effectiveness analysisOutcomes of Elective Aortic Hemiarch Reconstruction for Aneurysmal Disease in the Elderly
Kilic A, Arnaoutakis GJ, Bavaria JE, Sultan I, Desai ND, Vallabhajosyula P, Williams ML, Milewski RK, Szeto WY. Outcomes of Elective Aortic Hemiarch Reconstruction for Aneurysmal Disease in the Elderly. The Annals Of Thoracic Surgery 2017, 104: 1522-1530. PMID: 28648536, DOI: 10.1016/j.athoracsur.2017.03.067.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overAorta, ThoracicAortic Aneurysm, ThoracicBlood Vessel Prosthesis ImplantationCirculatory Arrest, Deep Hypothermia InducedCohort StudiesElective Surgical ProceduresFemaleGeriatric AssessmentHospital MortalityHumansMaleMiddle AgedPlastic Surgery ProceduresPostoperative CarePostoperative ComplicationsPrognosisPropensity ScoreRegistriesRetrospective StudiesRisk AssessmentSex FactorsSurvival AnalysisTreatment OutcomeConceptsModerate hypothermic circulatory arrestAntegrade cerebral perfusionHypothermic circulatory arrestHemiarch reconstructionElderly patientsAneurysmal diseaseOperative mortalityCerebral perfusionCirculatory arrestConcomitant aortic valve replacementRisk-adjusted operative mortalityCoronary artery bypassOperative mortality rateAortic valve replacementGreater comorbidity burdenLow operative mortalityOverall stroke rateSafe strategyIntensive care unitComorbidity burdenArtery bypassHospital stayRoot replacementValve replacementCare unit
2016
New Ventricular Septal Defects Following Balloon-Expandable Transcatheter Aortic Valve Replacement.
Rene AG, Jagasia D, Wickramasinghe SR, Desai N, Szeto W, Vallabhajosyula P, Li RH, Silvestry FE, Giri J, Jha S, Herrmann HC, Anwaruddin S. New Ventricular Septal Defects Following Balloon-Expandable Transcatheter Aortic Valve Replacement. Journal Of Invasive Cardiology 2016, 28: e59-65. PMID: 27342207.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAortic ValveAortic Valve StenosisEchocardiographyFemaleHeart Septal Defects, VentricularHumansMaleOutcome and Process Assessment, Health CarePostoperative ComplicationsQuality of LifeReoperationRisk AssessmentRisk FactorsSeverity of Illness IndexTranscatheter Aortic Valve ReplacementConceptsTranscatheter aortic valve replacementLeft ventricular outflow tract calcificationSevere symptomatic aortic stenosisVentricular outflow tract calcificationSymptomatic aortic stenosisAortic valve replacementVentricular septal defectNew ventricular septal defectQuality of lifeInoperable patientsInfrequent complicationParavalvular regurgitationValve replacementAortic stenosisVascular injurySeptal defectPatientsComplicationsStudied populationRegurgitationStenosisInjuryStrokeCalcificationBicuspid Aortic Insufficiency With Aortic Root Aneurysm: Root Reimplantation Versus Bentall Root Replacement
Vallabhajosyula P, Szeto WY, Habertheuer A, Komlo C, Milewski RK, McCarthy F, Desai ND, Bavaria JE. Bicuspid Aortic Insufficiency With Aortic Root Aneurysm: Root Reimplantation Versus Bentall Root Replacement. The Annals Of Thoracic Surgery 2016, 102: 1221-1228. PMID: 27261086, DOI: 10.1016/j.athoracsur.2016.03.087.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAorta, ThoracicAortic Aneurysm, ThoracicAortic ValveAortic Valve InsufficiencyBicuspid Aortic Valve DiseaseBlood Vessel Prosthesis ImplantationCombined Modality TherapyDatabases, FactualEchocardiography, TransesophagealFemaleFollow-Up StudiesHeart Valve DiseasesHeart Valve Prosthesis ImplantationHumansMaleMiddle AgedPreoperative CareRetrospective StudiesRisk AssessmentSurvival RateTime FactorsTreatment OutcomeVascular Surgical ProceduresConceptsAortic insufficiencyBicuspid aortic valveBentall groupRoot replacementRoot reimplantationAortic valveCusp repairRoot aneurysmFive-year actuarial survivalValve-sparing root reimplantationBicuspid aortic insufficiencyHospital stroke ratePermanent pacemaker rateTransient ischemic attackVentricular diastolic diameterLow ejection fractionAortic root aneurysmAortic root proceduresActuarial survivalAortic reoperationDischarge echocardiographyHospital mortalityIschemic attackVSRR groupBentall procedureAt the Root of the Repair Debate: Outcomes After Elective Aortic Root Replacements for Aortic Insufficiency With Aneurysm
McCarthy FH, Bavaria JE, McDermott KM, Moeller P, Spragan D, Hoedt A, Dibble T, Savino D, Williams ML, Vallabhajosyula P, Szeto WY, Desai ND. At the Root of the Repair Debate: Outcomes After Elective Aortic Root Replacements for Aortic Insufficiency With Aneurysm. The Annals Of Thoracic Surgery 2016, 102: 1199-1205. PMID: 27261085, DOI: 10.1016/j.athoracsur.2016.03.071.Peer-Reviewed Original ResearchMeSH KeywordsAdultAortic Aneurysm, ThoracicAortic Valve InsufficiencyBlood Vessel Prosthesis ImplantationCause of DeathDatabases, FactualElective Surgical ProceduresFemaleFollow-Up StudiesHeart Valve Prosthesis ImplantationHospital MortalityHumansKaplan-Meier EstimateMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesRisk AssessmentSurvival AnalysisTreatment OutcomeConceptsModerate aortic insufficiencySevere aortic insufficiencyAortic insufficiencyLong-term survivalRoot replacementWorse survivalAI patientsDecreased long-term survivalElective aortic root replacementWorse long-term survivalPreoperative aortic insufficiencyPreoperative renal failureAortic root replacementAppropriate therapeutic strategiesGreater aortic insufficiencyTiming of interventionUnited States populationRenal failureYounger patientsMultivariable predictorsSimilar patientsAortic aneurysmSingle institutionInclusion criteriaSimilar survival
2015
Outcomes of transcatheter aortic valve replacement in patients with chronic liver disease
Shah AM, Ogbara J, Herrmann HC, Fox Z, Kadakia M, Anwaruddin S, Bavaria JE, Desai ND, Jagasia D, Szeto WY, Li RH, Vallabhajosyula P, Giri J. Outcomes of transcatheter aortic valve replacement in patients with chronic liver disease. Catheterization And Cardiovascular Interventions 2015, 86: 888-894. PMID: 25963625, DOI: 10.1002/ccd.25994.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisBioprosthesisBiopsyCardiac CatheterizationChronic DiseaseFeasibility StudiesFemaleFemoral ArteryHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHospital MortalityHumansLiver DiseasesMaleMiddle AgedPatient SelectionRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeConceptsTranscatheter aortic valve replacementChronic liver diseaseValve Academic Research ConsortiumAcute kidney injuryAortic valve replacementLiver diseaseLate deathsKidney injuryValve replacementUnknown causeTransapical (TA) TAVRRole of TAVRTA TAVRSevere symptomatic aortic valve stenosisModerate chronic liver diseaseSymptomatic aortic valve stenosisAdvanced liver diseaseMajor bleeding complicationsNon-cardiac causesOutcomes of patientsTransient ischemic attackAcademic Research ConsortiumHigh-risk surgeryAortic valve stenosisLong-term follow
2014
Extracorporeal life support as rescue strategy for out-of-hospital and emergency department cardiac arrest
Johnson NJ, Acker M, Hsu CH, Desai N, Vallabhajosyula P, Lazar S, Horak J, Wald J, McCarthy F, Rame E, Gray K, Perman SM, Becker L, Cowie D, Grossestreuer A, Smith T, Gaieski DF. Extracorporeal life support as rescue strategy for out-of-hospital and emergency department cardiac arrest. Resuscitation 2014, 85: 1527-1532. PMID: 25201611, DOI: 10.1016/j.resuscitation.2014.08.028.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAdultAgedCardiopulmonary ResuscitationConfidence IntervalsEmergency Service, HospitalExtracorporeal Membrane OxygenationFemaleFollow-Up StudiesHeart ArrestHospital MortalityHumansLife Support SystemsMaleMiddle AgedOut-of-Hospital Cardiac ArrestPhiladelphiaProspective StudiesRegistriesRisk AssessmentSurvival AnalysisTreatment OutcomeConceptsEmergency department cardiac arrestED cardiac arrestCardiac arrestLife supportRescue strategyUrban academic medical centerInitiation of ECLSHours of admissionInitial cardiac rhythmExtracorporeal life supportPulseless ventricular tachycardiaInitial cardiac arrestConventional cardiopulmonary resuscitationAcademic medical centerHospital dischargeIschemic eventsConsecutive patientsPrimary outcomePatient selectionInstitution experienceVentricular tachycardiaECLS cannulationVentricular fibrillationCardiopulmonary resuscitationMedical CenterType A Aortic Dissection After Previous Cardiac Surgery: Results of an Integrated Surgical Approach
Rylski B, Desai ND, Bavaria JE, Moser W, Vallabhajosyula P, Pochettino A, Szeto WY, Milewski RK. Type A Aortic Dissection After Previous Cardiac Surgery: Results of an Integrated Surgical Approach. The Annals Of Thoracic Surgery 2014, 97: 1582-1589. PMID: 24629304, DOI: 10.1016/j.athoracsur.2013.12.064.Peer-Reviewed Original ResearchMeSH KeywordsAgedAortic Aneurysm, ThoracicAortic DissectionBlood Vessel Prosthesis ImplantationCardiac Surgical ProceduresCause of DeathCohort StudiesFemaleFollow-Up StudiesHospital MortalityHumansKaplan-Meier EstimateLength of StayMaleMiddle AgedPatient SafetyPostoperative ComplicationsRadiographyReoperationRetrospective StudiesRisk AssessmentSeverity of Illness IndexStatistics, NonparametricSurvival AnalysisTime FactorsTreatment OutcomeConceptsPrevious cardiac surgeryPCS patientsAortic dissectionCardiac surgeryAcute typeCardiac tamponadeHospital mortality risk factorsAcceptable postoperative mortalityPostoperative stroke ratePrior myocardial revascularizationA Aortic DissectionHospital mortality rateCoronary artery diseaseMortality risk factorsCoronary malperfusionHospital mortalityPostoperative mortalityAortic repairMyocardial revascularizationStanford typeArtery diseaseSurgical repairSurgical approachRisk factorsStroke rate