Sidi Chen, PhD

Assistant Professor

Departments & Organizations

Genetics: Sidi Chen Lab

Liver Center

Stem Cell Center, Yale

Yale Cancer Center: Genomics, Genetics, and Epigenetics

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Immunology | Molecular Cell Biology, Genetics and Development


I earned my PhD from The University of Chicago, and performed postdoctoral studies at MIT and the Broad Institute. My research focuses on global understanding of biological systems. I have led studies on identifying and characterizing genes of new origin in eukaryotic genomes, essential function of new genes in animal development and tumorigenesis, microRNA regulation of hypoxia and angiogenesis, in vivo modeling of lung cancer and liver cancer using gene editing, and genome-wide in vivo screens. My research team is interested in developing and applying novel tools for next generation cancer genetics, genomics and systems biology, and tackle problems in cancer initiation, progression, metastasis, immunity, and therapeutic responses.

Education & Training

PhD The University of Chicago (2011)
Visiting Postdoc Broad Institute of MIT and Harvard
Postdoctoral Fellow MIT
Visiting Student Stanford University

Honors & Recognition

  • Bohmfalk Scholar in Medical Research (2017)

  • LCRP Idea Development AwardDepartment of Defense (2017)

  • AACR NextGen Award for Transformative Cancer ResearchAACR (2017)

  • Exceptional Research Grant AwardBreast Cancer Alliance (2017)

  • St. Baldrick’s Foundation Award (2016)

  • Young Investigator AwardMelanoma Research Alliance (2016)

  • Dale Frey Award for Breakthrough ScientistsDamon Runyon Cancer Research Foundation (2015)

  • Damon Runyon Cancer Research FellowshipDamon Runyon Cancer Research Foundation (2012)

  • Best Dissertation AwardThe University of Chicago (2011)

  • Chair’s Special Award, Best PresentationGordon Research Conference (2011)

  • National Science Foundation Doctoral Dissertation Improvement GrantNational Science Foundation (2010)

  • Chun-Tsung ScholarTsung-Dao Lee Foundation (2002)

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Contact Info

Sidi Chen, PhD
Lab Location
Sidi Chen LaboratoryWest Campus Integrative Science & Technology Center
850 West Campus Drive, Rm 314

West Haven, CT 06516
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Mailing Address
Genetics850 West Campus Drive
Integrated Science & Technology Center

West Haven, CT 06516

Curriculum Vitae

Chen Lab website