Positions available in the Lab of Patrick Gallagher

Position Information

Postdoctoral Position in Pediatrics and Genetics

Posting Date:April 2018

Seeking a highly motivated and dedicated individual for a position as a postdoctoral associate in the laboratory of Dr. Patrick Gallagher. The research goal of the Gallagher Lab is to gain a better of understanding of hematopoiesis and erythropoiesis, particularly in humans.

We apply this knowledge to the diagnosis and treatment of inherited and acquired hematologic disease, seeking to understand the mechanisms underlying human blood disorders. With this knowledge, preventative strategies and appropriate diagnostic algorithms can be created for patients afflicted by these diseases. Laboratory projects employ a broad range of techniques, including molecular biology, cell biology, physiology, genetics and genomics.

We have applied genomic strategies, including mRNA and microRNA expression profiling, single cell sequencing, RNA seq, ChIP-chip and ChIP-seq technology, ATAC sequencing, meDIP and other methylation studies, as well as novel phosphoproteomic and quantitative proteomic techniques, to our understanding of hematopoiesis. We utilize erythroid cells and specific membrane protein gene loci as models of regulation of complex genetic loci, a model which has many benefits. The genes are large and are represented by many cell, tissue, and developmental stage-specific isoforms. We employ a number of cellular models including hematopoietic stem cells, ES cells, iPS cells, and transformed cell lines.

We are seeking an individual with a strong background in molecular biology, genetics/genomics, cell biology, and/or physiology. Candidates should have a background in cell and molecular biology, biochemistry, genetics and genomics or other related fields with a Ph.D. and/or M.D. degree. Individuals with training and a track record of accomplishments in hematopoiesis, erythropoiesis or related areas are strongly encouraged to apply. Successful candidates are independent, innovative, and able to actively lead complex research projects. Excellent written and oral English communication skills are mandatory. Substantial consideration will be given to personal suitability during the selection process. Please clearly specify your skills in your application. Additional information about postdoctoral positions at Yale University can be found at https://postdocs.yale.edu/ and https://medicine.yale.edu/gateways/postdocs.aspx.

If you are interested in this position, please send (1) your CV, (2) 3 references, (3) a brief description of previous research experience and (4) an unofficial transcript to Dr. Patrick G. Gallagher, c/o Rosemary Rubsam rosemary.rubsam@yale.edu

Yale University is an Affirmative Action/Equal Opportunity Employer and welcomes applications from women, members of minority groups, persons with disabilities and protected veterans.

 

Postgraduate Position in Pediatrics and Genetics

Posting Date: April 2018

Seeking a highly motivated and dedicated recent college graduate for a position as a postgraduate associate in the laboratory of Dr. Patrick Gallagher. The research goal of the Gallagher Lab is to gain a better of understanding of hematopoiesis and erythropoiesis, particularly in humans.

We apply this knowledge to the diagnosis and treatment of inherited and acquired hematologic disease, seeking to understand the mechanisms underlying human blood disorders. With this knowledge, preventative strategies and appropriate diagnostic algorithms can be created for patients afflicted by these diseases. Laboratory projects employ a broad range of techniques, including molecular biology, cell biology, physiology, genetics and genomics.

We have applied genomic strategies, including mRNA and microRNA expression profiling, single cell sequencing, RNA seq, ChIP-chip and ChIP-seq technology, ATAC sequencing, meDIP and other methylation studies, as well as novel phosphoproteomic and quantitative proteomic techniques, to our understanding of hematopoiesis. We utilize erythroid cells and specific membrane protein gene loci as models of regulation of complex genetic loci, a model which has many benefits. The genes are large and are represented by many cell, tissue, and developmental stage-specific isoforms. We employ a number of cellular models including hematopoietic stem cells, ES cells, iPS cells, and transformed cell lines.  Prior research experience using basic molecular or cell biology techniques or animal models is a plus but not required.

The ideal candidate has majored in a science disciple, e.g. biology, molecular biology, biochemistry, and is seeking advanced training for a defined period of time. The candidate will have opportunities to present his/her data at group laboratory meetings and at formal intramural and national/international conferences. The overall goal is to learn how to design and perform scientific experiments that can be used to develop his/her basis for a future career in science and/or medicine. The position is for 1 year, extendable to 2 years, with immediate start availability. If you are interested in this position, please send (1) your CV, (2) 3 references, (3) a brief description of previous research experience and (4) an unofficial transcript to Dr. Patrick Gallagher, c/o Rosemary Rubsam, rosemary.rubsam@yale.edu.

Yale University is an Affirmative Action/Equal Opportunity Employer and welcomes applications from women, members of minority groups, persons with disabilities and protected veterans