BEGIN:VCALENDAR PRODID:-//github.com/ical-org/ical.net//NONSGML ical.net 4.0//EN VERSION:2.0 BEGIN:VTIMEZONE TZID:America/New_York X-LIC-LOCATION:America/New_York BEGIN:STANDARD DTSTART:20241103T020000 RRULE:FREQ=YEARLY;BYDAY=1SU;BYMONTH=11 TZNAME:EST TZOFFSETFROM:-0400 TZOFFSETTO:-0500 END:STANDARD BEGIN:DAYLIGHT DTSTART:20250309T020000 RRULE:FREQ=YEARLY;BYDAY=2SU;BYMONTH=3 TZNAME:EDT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 END:DAYLIGHT END:VTIMEZONE BEGIN:VEVENT DESCRIPTION:Join us for a dean’s workshop on advanced genetic therapies\, titled “End-to-End Precision Genetic Therapies: From Emerging Technologie s to Patient Delivery” on Monday\, Nov. 2\, from 1 - 4:30 p.m . This work shop brings together leaders from across Yale and the broader precision g enetics community to discuss the latest advances in the field. Our scient ists and clinicians\, together with representatives from the NIH\, regula tory and biopharmaceutical sectors\, and the patient advocacy community\, will discuss next-generation gene-editing and delivery platforms and the ir application in the clinic across rare genetic disorders. The event wil l feature two keynote addresses:P.J. Brooks\, PhD \, acting director of t he Division of Rare Diseases Research Innovation at the NIH’s National Ce nter for Advancing Translational Sciences\, and co-chair of the NIH’s Bes poke Gene Therapy Consortium and Somatic Cell Genome Editing Programs\, w ill open the workshop on the future of gene editing. Peter Marks\, MD\, P hD \, our former colleague and a former director of the FDA’s Center for Biologics Evaluation and Research\, now senior vice president\, Molecule Discovery and head of infectious disease at Eli Lilly\, will deliver the closing keynote on the evolving regulatory landscape.The afternoon conclu des with a panel discussion\, “Precision Genetic Medicine: From Promise t o Practice\,” convening regulatory\, clinical\, and patient-advocacy lead ers to explore the infrastructure\, regulatory\, and health-system challe nges of bringing these therapies to patients.This hybrid event\, hosted b y the School of Medicine dean’s office\, will take place in person in Bra dy Auditorium\, B131 (310 Cedar Street)\, and via Zoom. WELCOME\, 1 – 1:0 5 PM Nancy J. Brown\, MD\, Jean and David W. Wallace Dean of Medicine and C.N.H. Long Professor of Internal Medicine\, Yale School of Medicine GEN E EDITING DELIVERY TECHNOLOGIES\, 1:05 – 2:25 PM Moderator: Monkol Lek\, PhD\, Associate Professor of Genetics\, Yale School of MedicineOPENING KE YNOTE: THE NIH SOMATIC CELL GENOME EDITING PROGRAM AND THE FUTURE OF GENE EDITING AS A THERAPEUTIC PLATFORM\, 1:05 – 1:45 PMP.J. Brooks\, PhD\, Ac ting Director\, Division of Rare Diseases Research Innovation\, National Center for Advancing Translational Sciences\, NIH\; and Co-Chair of the N IH’s Bespoke Gene Therapy Consortium and Somatic Cell Genome Editing Prog ramsNON-VIRAL DELIVERY OF GENE THERAPY: POLYMERIC NANOPARTICLES\, 1:45 - 2:05 PMMark W. Saltzman\, PhD\, Sterling Professor of Biomedical Engineer ing\; Faculty Director\, Center for Engineering Innovation and Design\; a nd Deputy Dean for Academic Affairs\, Yale Engineering\; and Head\, Jonat han Edwards College\, Yale UniversityNON-VIRAL DELIVERY OF GENE THERAPY: LIPID NANOPARTICLES AND STEP\, 2:05 - 2:25 PMJiangbing Zhou\, PhD\, Nixdo rff-German Professor of Neurosurgery\, Yale School of Medicine\; and Prof essor of Biomedical Engineering\, Yale EngineeringNETWORKING BREAK\, 2:25 - 2:40 PM GENE EDITING: PATH TO THE CLINIC\, 2:40 - 4:00 PM Moderator: P eter Glazer\, MD\, PhD\, Robert E. Hunter Professor and Chair of Therapeu tic Radiology\, and Professor of Genetics\, Yale School of MedicineINNOVA TIVE GENOME AND EPIGENOME EDITING–BASED THERAPIES FOR NEUROGENETIC DISORD ERS\, 2:40 - 3:00 PMYong-Hui Jiang\, MD\, PhD\, Professor of Genetics\, o f Pediatrics\, and of Obstetrics\, Gynecology\, and Reproductive Sciences \, and Dorys McConnell Duberg Professor of Neuroscience\, Yale School of Medicine\; and Chief of Medical Genetics\, Yale New Haven Health System G ENE-EDITING PLATFORMS TO ADDRESS CYSTIC FIBROSIS\, 3:00 - 3:20 PMMarie Eg an\, MD\, Professor of Pediatrics and of Cellular and Molecular Physiolog y\; Director\, Cystic Fibrosis Center\; Vice Chair of Research\, Departme nt of Pediatrics\, Yale School of Medicine\; and Chief\, Pediatric Pulmon ary\, Allergy\, and Sleep Medicine\; Yale New Haven Health System CLOSING KEYNOTE: A POTENTIAL REGULATORY FRAMEWORK FOR GENE-EDITING THERAPIES\, 3 :20 - 4:00 PMPeter Marks\, MD\, PhD\, Senior Vice President\, Molecule Di scovery and Head of Infectious Disease\, Eli Lilly and Company PANEL: PRE CISION GENETIC MEDICINE: FROM PROMISE TO PRACTICE\, 4:00 - 4:25 PM Modera tor: Marie Egan\, MD\, Professor of Pediatrics and of Cellular and Molecu lar Physiology\; Director\, Cystic Fibrosis Center\; Vice Chair of Resear ch\, Department of Pediatrics\, Yale School of Medicine\; and Chief\, Ped iatric Pulmonary\, Allergy\, and Sleep Medicine\; Yale New Haven Health S ystem A DISCUSSION OF INFRASTRUCTURE\, REGULATION\, AND CLINICAL SYSTEMSP anelists: Allyson Berent\, DVM\, Dipl. ACVIM\, Chief Science Officer\, Fo undation for Angelman Syndrome Therapeutics\; and Chief Development Offic er\, AS²BioBeth Heinz\, MHA\, MSW\, Senior Vice President\, Women’s & Chi ldren’s Services\, Yale New Haven HospitalLakshmanan Krishnamurti\, MD\, Professor of Pediatrics\, Yale School of Medicine and Chief\, Section of Pediatric Hematology/Oncology/BMT\, Yale New Haven Health SystemPeter Mar ks\, MD\, PhD\, Senior Vice President\, Molecule Discovery and Head of In fectious Disease\, Eli Lilly and CompanyCLOSING REMARKS\, 4:25 – 4:30 PM Nancy J. Brown\, MDThe workshop is being recorded and will be available o nline after the event at https://medicine.yale.edu/about/deanoffice/works hop\n\nSpeakers:\nNancy Brown\; Monkol Lek\; PJ Brooks\, PhD\; W. Mark Sa ltzman\; Jiangbing Zhou\; Peter Glazer\; Yong-Hui Jiang\; Marie Egan\; Pe ter Marks\, MD\, PhD\; Allyson Berent\, DVM\; Beth Heinz\, MHA\, MSW\; La kshmanan Krishnamurti\n\nAdmission:\nFree\n\nDetails URL:\nhttps://medici ne.yale.edu/event/deans-workshop-precision-genetic-therapies-nov-2-2026/\ n DTEND;TZID=America/New_York:20261102T170000 DTSTAMP:20260930T223814Z DTSTART;TZID=America/New_York:20261102T130000 LOCATION:URL: https://yale.zoom.us/j/93614615801 SEQUENCE:0 STATUS:Confirmed SUMMARY:Dean's Workshop UID:108029e0-a72c-4009-9128-bd8d8917178e END:VEVENT END:VCALENDAR