2014
Dysfunction and recovery in demyelinated and dysmyelinated axons
Waxman S. Dysfunction and recovery in demyelinated and dysmyelinated axons. 2014, 457-471. DOI: 10.1017/cbo9780511995583.034.Peer-Reviewed Original ResearchNervous systemNeural repairNormal central nervous systemSpinal cord damageRecovery of functionCentral nervous systemNeuron replacementCerebral palsyCord damageAxonal regenerationNeuronal deathAxon regenerationNeurological rehabilitationBrain disordersCell therapyRehabilitation professionalsRepairRehabilitationBasic scienceStem cell biologyPalsyDysfunctionPathophysiologyInjuryTherapy
2010
Sodium channel expression and function in multiple sclerosis
Bangalore L, Black J, Carrithers M, Waxman S. Sodium channel expression and function in multiple sclerosis. 2010, 29-43. DOI: 10.1017/cbo9780511781698.005.Peer-Reviewed Original ResearchMultiple sclerosisRecovery of functionSodium channel expressionHealth care advisorsMechanisms of recoveryNeurorehabilitation programChannel expressionSpecific syndromesTherapeutic interventionsCare advisorsClinical rehabilitationEfficient therapySclerosisDisease mechanismsPatientsCliniciansNeurorehabilitationInterventionBasic scienceSocial participationPathophysiologySyndromeTherapyNeuroplasticity
2006
Dysfunction and recovery in demyelinated and dysmyelinated axons
Waxman S. Dysfunction and recovery in demyelinated and dysmyelinated axons. 2006, 468-486. DOI: 10.1017/cbo9780511545061.029.Peer-Reviewed Original Research
1996
White Matter Stroke: Autoprotective Mechanisms with Therapeutic Implications
Fern R, Ransom B, Waxman S. White Matter Stroke: Autoprotective Mechanisms with Therapeutic Implications. Cerebrovascular Diseases 1996, 6: 59-65. DOI: 10.1159/000107999.Peer-Reviewed Original ResearchWhite matterAnoxic injuryWhite matter strokeIncidence of strokeCNS white matterLevels of GABARecovery of functionResult of anoxiaIrreversible dysfunctionAnoxic insultPharmacological strategiesIrreversible injuryTherapeutic implicationsEndogenous storesExogenous GABAInjuryGABAAutoprotective mechanismsStrokeIntracellular eventsExtracellular spaceCa2Protective treatmentAdenosineInflux
1989
Demyelination in spinal cord injury
Waxman S. Demyelination in spinal cord injury. Journal Of The Neurological Sciences 1989, 91: 1-14. PMID: 2664092, DOI: 10.1016/0022-510x(89)90072-5.Peer-Reviewed Original ResearchConceptsSpinal cord injuryCord injuryDemyelinated axonsFunctional recoveryCompressive spinal cord injuryAbsence of remyelinationRecovery of conductionRecovery of functionSmall-diameter axonsModification of conductionHemorrhagic necrosisPathophysiological basisClinical criteriaComplete transectionSchwann cellsDemyelinationDiameter axonsAction potentialsInjuryDemyelinated fibersAxonsRemyelinationNeurophysiological evidencePhysiological studiesTransection