2016
Fluorescence In situ Hybridization: Cell-Based Genetic Diagnostic and Research Applications
Cui C, Shu W, Li P. Fluorescence In situ Hybridization: Cell-Based Genetic Diagnostic and Research Applications. Frontiers In Cell And Developmental Biology 2016, 4: 89. PMID: 27656642, PMCID: PMC5011256, DOI: 10.3389/fcell.2016.00089.Peer-Reviewed Original ResearchSingle-molecule RNA FISHSingle nucleotide polymorphism (SNP) lociSingle gene levelSingle-copy sequencesGene-specific probesSingle-cell DNASitu hybridizationSingle cellsChromosomal organizationRNA FISHGenomic organizationTranscriptional dynamicsGenomic structurePhysical mapping toolChromosome haplotypesRepetitive sequencesRNA transcriptionMultiple genesBiological processesPolymorphism lociFISH technologyCombinatorial labelingGene levelMicrodeletion/microduplication syndromesLiving cells
2015
Copy number changes and methylation patterns in an isodicentric and a ring chromosome of 15q11-q13: report of two cases and review of literature
Wang Q, Wu W, Xu Z, Luo F, Zhou Q, Li P, Xie J. Copy number changes and methylation patterns in an isodicentric and a ring chromosome of 15q11-q13: report of two cases and review of literature. Molecular Cytogenetics 2015, 8: 97. PMID: 26697114, PMCID: PMC4687147, DOI: 10.1186/s13039-015-0198-4.Peer-Reviewed Original ResearchMethylation patternsCopy number changesLow-copy repeatsNumber changesChromosome 15Further gene expressionRing chromosomesSmall ring chromosomeGenomic structureEpigenetic patternsComparative genomic hybridization analysisPhenotypic consequencesGene expressionMb regionGenomic hybridization analysisChromosomesIntrachromosomal deletionsHybridization analysisMb segmentArray comparative genomic hybridization analysisMethylation-specific multiplex ligation-dependent probe amplificationCopy repeatsMS-MLPA analysisSitu hybridizationPhenotype correlation