2023
Effect of Exercise on Chemotherapy-Induced Peripheral Neuropathy Among Patients Treated for Ovarian Cancer
Cao A, Cartmel B, Li F, Gottlieb L, Harrigan M, Ligibel J, Gogoi R, Schwartz P, Esserman D, Irwin M, Ferrucci L. Effect of Exercise on Chemotherapy-Induced Peripheral Neuropathy Among Patients Treated for Ovarian Cancer. JAMA Network Open 2023, 6: e2326463. PMID: 37526937, PMCID: PMC10394582, DOI: 10.1001/jamanetworkopen.2023.26463.Peer-Reviewed Original ResearchConceptsChemotherapy-induced peripheral neuropathyAerobic exercise interventionAttention control armExercise intervention armExercise interventionOvarian cancerControl armIntervention armSecondary analysisCIPN symptomsPeripheral neuropathyLifestyle StudyTreatment of CIPNModerate-intensity aerobic exerciseStandard oncology careEffects of exerciseSevere adverse effectsBetween-group differencesAmerican Cancer SocietyQuality of lifeAttention controlCIPN severityPrimary outcomeOncology careAerobic exercise
2022
Effect of exercise on body composition among women with ovarian cancer
Cao A, Cartmel B, Li FY, Gottlieb LT, Harrigan M, Ligibel JA, Gogoi R, Schwartz PE, Irwin ML, Ferrucci LM. Effect of exercise on body composition among women with ovarian cancer. Journal Of Cancer Survivorship 2022, 17: 1386-1396. PMID: 35377104, PMCID: PMC9530065, DOI: 10.1007/s11764-022-01207-x.Peer-Reviewed Original ResearchConceptsDual-energy X-ray absorptiometryOvarian cancer survivorsAerobic exercise interventionEffects of exerciseCancer survivorsOvarian cancerExercise interventionBody compositionSix-month aerobic exercise interventionBone mineral densityBetween-group differencesBody fat percentageLean body massX-ray absorptiometrySecondary outcomesStudy armsAerobic exerciseLifestyle StudyMineral densityHigh riskCancerSurvivorsFat percentageWomenResultsOn average
2010
Adiposity changes after a 1-year aerobic exercise intervention among postmenopausal women: a randomized controlled trial
Friedenreich C, Woolcott C, McTiernan A, Terry T, Brant R, Ballard-Barbash R, Irwin M, Jones C, Boyd N, Yaffe M, Campbell K, McNeely M, Karvinen K, Courneya K. Adiposity changes after a 1-year aerobic exercise intervention among postmenopausal women: a randomized controlled trial. International Journal Of Obesity 2010, 35: 427-435. PMID: 20820172, PMCID: PMC3061001, DOI: 10.1038/ijo.2010.147.Peer-Reviewed Original ResearchConceptsAerobic exercise interventionTotal body fatExercise interventionPostmenopausal womenFat areaBody fatGreater body fat lossSubcutaneous abdominal fat areaCurrent public health guidelinesIntra-abdominal fat areaSedentary postmenopausal womenAbdominal fat areaAerobic exercise programExercise five timesBody fat lossDual-energy X-ray absorptiometry measurementsBreast cancer riskVolume of exerciseMeasures of adiposityPublic health guidelinesComputerized tomography measurementsExercise groupObese womenAbdominal adiposityExercise program
2009
Exercise Improves Body Fat, Lean Mass, and Bone Mass in Breast Cancer Survivors
Irwin ML, Alvarez‐Reeves M, Cadmus L, Mierzejewski E, Mayne ST, Yu H, Chung GG, Jones B, Knobf MT, DiPietro L. Exercise Improves Body Fat, Lean Mass, and Bone Mass in Breast Cancer Survivors. Obesity 2009, 17: 1534-1541. PMID: 19629060, PMCID: PMC2841468, DOI: 10.1038/oby.2009.18.Peer-Reviewed Original ResearchConceptsModerate-intensity aerobic exerciseUsual care participantsBreast cancer survivorsMin/weekDual-energy X-ray absorptiometryUsual care groupBone mineral densityCancer survivorsAerobic exerciseCare participantsLean massBody fatBody compositionCare groupBone massYale-New Haven Hospital Tumor RegistryPostmenopausal breast cancer survivorsCurrent physical activity levelsHospital tumor registryAerobic exercise interventionPhysical activity levelsBreast cancer prognosisPercent body fatX-ray absorptiometryBreast cancer diagnosisRandomized Controlled Trial of Aerobic Exercise on Insulin and Insulin-like Growth Factors in Breast Cancer Survivors: The Yale Exercise and Survivorship Study
Irwin ML, Varma K, Alvarez-Reeves M, Cadmus L, Wiley A, Chung GG, DiPietro L, Mayne ST, Yu H. Randomized Controlled Trial of Aerobic Exercise on Insulin and Insulin-like Growth Factors in Breast Cancer Survivors: The Yale Exercise and Survivorship Study. Cancer Epidemiology Biomarkers & Prevention 2009, 18: 306-313. PMID: 19124513, PMCID: PMC2841479, DOI: 10.1158/1055-9965.epi-08-0531.Peer-Reviewed Original ResearchConceptsBreast cancer survivorsPostmenopausal breast cancer survivorsModerate-intensity aerobic exerciseUsual care groupBreast cancer riskAerobic exerciseIGFBP-3Cancer survivorsUsual careCare groupCancer riskYale-New Haven Hospital Tumor RegistryCurrent physical activity levelsInsulin-like growth factorHospital tumor registryUsual care participantsAerobic exercise interventionExercise-induced decreasePhysical activity levelsInsulin-like growthExercise groupExercise interventionControlled TrialsTumor RegistryBrisk walking