Clinical challenges and advancements in diagnosing Staphylococcus aureus-associated musculoskeletal infections
Oh I. Clinical challenges and advancements in diagnosing Staphylococcus aureus-associated musculoskeletal infections. Kosin Medical Journal 2024, 39: 5-17. DOI: 10.7180/kmj.24.104.Peer-Reviewed Original ResearchMusculoskeletal infectionsS. aureus immune evasionIdentification of pathogensNext-generation sequencingConventional culture methodsComplicated clinical decisionsDevelopment of innovative diagnosticsPeripheral blood mononuclear cellsRemoval of infected implantsErythrocyte sedimentation rateMonitoring treatment responseTranscriptome of peripheral blood mononuclear cellsBlood mononuclear cellsC-reactive proteinFalse-negative resultsStaphylococcus aureusDominant pathogenAntibiotic therapySurgical debridementAbscess formationInfected implantsInflammatory markersAggressive debridementInfected tissuesOrthopedic infections