2019
Echocardiographic Assessment of Right Ventricular Function and Response to Therapy in Pulmonary Arterial Hypertension
Shelburne NJ, Parikh KS, Chiswell K, Shaw LK, Sivak J, Arges K, Tomfohr J, Velazquez EJ, Kisslo J, Samad Z, Rajagopal S. Echocardiographic Assessment of Right Ventricular Function and Response to Therapy in Pulmonary Arterial Hypertension. The American Journal Of Cardiology 2019, 124: 1298-1304. PMID: 31481176, DOI: 10.1016/j.amjcard.2019.07.026.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAntihypertensive AgentsEchocardiographyExercise TestFemaleFollow-Up StudiesHeart VentriclesHumansMaleMiddle AgedNorth CarolinaPrognosisPulmonary Arterial HypertensionRetrospective StudiesSeverity of Illness IndexStroke VolumeSurvival RateVentricular Function, RightYoung AdultConceptsTricuspid annular plane systolic excursionPulmonary arterial hypertensionRV global longitudinal strainRV systolic pressureRight ventricular functionGlobal longitudinal strainArterial hypertensionSystolic pressureVentricular functionSevere pulmonary arterial hypertensionAnnular plane systolic excursionLongitudinal strainPAH-specific therapyManagement of patientsRight atrial areaMid-RVPAH therapyCause mortalityEchocardiographic parametersClinical responseEchocardiographic variablesSystolic excursionWalk distanceEchocardiographic assessmentAtrial area
2018
Tricuspid Valve Regurgitation Immediately After Heart Transplant and Long-Term Outcomes
Bishawi M, Zanotti G, Shaw L, MacKenzie M, Castleberry A, Bartels K, Schroder J, Velazquez E, Swaminathan M, Rogers J, Milano C. Tricuspid Valve Regurgitation Immediately After Heart Transplant and Long-Term Outcomes. The Annals Of Thoracic Surgery 2018, 107: 1348-1355. PMID: 30529215, PMCID: PMC7256852, DOI: 10.1016/j.athoracsur.2018.10.065.Peer-Reviewed Original ResearchConceptsSignificant tricuspid valve regurgitationTricuspid valve regurgitationLong-term outcomesHeart transplantationCardiopulmonary bypassTR gradeValve regurgitationSurgical repairValve repairCommon findingOrthotropic heart transplantationPostoperative plasma creatininePulmonary vascular resistanceTricuspid valve repairEarly surgical repairEarly morbidityPostoperative stayCardiac transplantationMultiorgan transplantsVascular resistanceTransplant databaseHeart transplantAdjusted survivalPlasma creatinineTransplant
2017
Clinical characteristics and 12-month outcomes of patients with valvular and non-valvular atrial fibrillation in Kenya
Temu TM, Lane KA, Shen C, Ng'ang'a L, Akwanalo CO, Chen PS, Emonyi W, Heckbert SR, Koech MM, Manji I, Vatta M, Velazquez EJ, Wessel J, Kimaiyo S, Inui TS, Bloomfield GS. Clinical characteristics and 12-month outcomes of patients with valvular and non-valvular atrial fibrillation in Kenya. PLOS ONE 2017, 12: e0185204. PMID: 28934312, PMCID: PMC5608343, DOI: 10.1371/journal.pone.0185204.Peer-Reviewed Original ResearchConceptsValvular AFValvular heart diseaseAtrial fibrillationNVAF patientsAF patientsHeart diseaseNon-valvular atrial fibrillationGlobal cardiovascular disease burdenValvular atrial fibrillationRates of hypertensionCardiovascular disease burdenLong-term outcomesProspective data collectionAnticoagulation therapyClinical characteristicsCohort studyClinical profileHeart failureOverall mortalityClinical featuresComorbid conditionsFatal outcomeMean ageFemale sexDisease burdenHousehold Air Pollution Is Associated with Altered Cardiac Function among Women in Kenya
Agarwal A, Kirwa K, Eliot MN, Alenezi F, Menya D, Mitter SS, Velazquez EJ, Vedanthan R, Wellenius GA, Bloomfield GS. Household Air Pollution Is Associated with Altered Cardiac Function among Women in Kenya. American Journal Of Respiratory And Critical Care Medicine 2017, 197: 958-961. PMID: 28925740, PMCID: PMC6020413, DOI: 10.1164/rccm.201704-0832le.Peer-Reviewed Original ResearchAssessment of cardiac allograft systolic function by global longitudinal strain: From donor to recipient
DeVore AD, Alenezi F, Krishnamoorthy A, Ersboll M, Samsky MD, Schulte PJ, Patel CB, Rogers JG, Milano CA, Velazquez EJ, Khouri MG. Assessment of cardiac allograft systolic function by global longitudinal strain: From donor to recipient. Clinical Transplantation 2017, 31: e12961. PMID: 28294407, DOI: 10.1111/ctr.12961.Peer-Reviewed Original ResearchConceptsLV global longitudinal strainLeft ventricular ejection fractionGlobal longitudinal strainMedian left ventricular ejection fractionSystolic functionLongitudinal strainLV systolic dysfunctionMyocardial systolic performancePost-transplant outcomesLV systolic functionVentricular ejection fractionDonor-recipient pairsMyocardial deformation analysisAllograft dysfunctionCardiac allograftsCause hospitalizationSystolic dysfunctionPretransplant levelsEjection fractionSystolic performanceCorresponding recipientsClinical implicationsRecipientsEchocardiogramFurther studies
2014
Blood pressure level impacts risk of death among HIV seropositive adults in Kenya: a retrospective analysis of electronic health records
Bloomfield GS, Hogan JW, Keter A, Holland TL, Sang E, Kimaiyo S, Velazquez EJ. Blood pressure level impacts risk of death among HIV seropositive adults in Kenya: a retrospective analysis of electronic health records. BMC Infectious Diseases 2014, 14: 284. PMID: 24886474, PMCID: PMC4046023, DOI: 10.1186/1471-2334-14-284.Peer-Reviewed Original ResearchConceptsSystolic blood pressureLower blood pressureHigher systolic blood pressureCardiovascular risk factorsBlood pressure levelsBlood pressureHigh blood pressureHigher mortality riskMortality rateHazard ratioRisk factorsIncidence rateRetrospective analysisMortality riskLarge HIV treatment programHuman immunodeficiency virus (HIV) infectionNormal systolic blood pressureProportional hazards regression modelsCox proportional hazards modelAdvanced HIV diseaseNon-communicable causeHIV-seropositive individualsHIV-seropositive adultsImmunodeficiency virus infectionHIV treatment programs
2011
Hypertension and Obesity as Cardiovascular Risk Factors among HIV Seropositive Patients in Western Kenya
Bloomfield GS, Hogan JW, Keter A, Sang E, Carter EJ, Velazquez EJ, Kimaiyo S. Hypertension and Obesity as Cardiovascular Risk Factors among HIV Seropositive Patients in Western Kenya. PLOS ONE 2011, 6: e22288. PMID: 21779407, PMCID: PMC3136516, DOI: 10.1371/journal.pone.0022288.Peer-Reviewed Original ResearchConceptsPrevalence of hypertensionOverweight/obesityLarge HIV treatment programCardiovascular risk factorsHIV treatment programsLogistic regression analysisRisk factorsSystolic/diastolic blood pressureAssociated cardiovascular risk factorsTreatment programMultiple logistic regression analysisHIV-seropositive individualsHIV-seropositive patientsDiastolic blood pressureOverweight/obesePrevalence of HIVPercent of menAge categoriesOrdinal logistic regression analysisRegression analysisHigher age categoriesElectronic medical recordsWestern KenyaCD4 countSeropositive patients
2008
The design of an observational study of hypertension management, adherence and pressure control in Blood Pressure Success Zone Program participants
Payne K, J. J, Daley W, Khan Z, Ishak K, Stark K, Purkayastha D, Flack J, Velázquez E, Nesbitt S, Morisky D, Califf R, Committee F. The design of an observational study of hypertension management, adherence and pressure control in Blood Pressure Success Zone Program participants. International Journal Of Clinical Practice 2008, 62: 1313-1321. PMID: 18647193, PMCID: PMC2658016, DOI: 10.1111/j.1742-1241.2008.01840.x.Peer-Reviewed Original ResearchConceptsAntihypertensive medicationsObservational studyInteractive voice response systemPressure controlUsual care visitsBlood pressure controlLongitudinal observational studyHealth education programsUsual careCare visitsEligible subjectsTreatment satisfactionHypertension managementPatient satisfactionStudy completionHealthcare databasesVoice response systemProgram participantsMedicationsStudy designPhysiciansAdherenceProgram enrollmentEnrollmentNationwide initiative