2019
Association between systolic ejection time and outcomes in heart failure by ejection fraction
Patel PA, Ambrosy AP, Phelan M, Alenezi F, Chiswell K, Van Dyke MK, Tomfohr J, Honarpour N, Velazquez EJ. Association between systolic ejection time and outcomes in heart failure by ejection fraction. European Journal Of Heart Failure 2019, 22: 1174-1182. PMID: 31863532, PMCID: PMC7493053, DOI: 10.1002/ejhf.1659.Peer-Reviewed Original ResearchConceptsSystolic ejection timeEjection fractionHeart failureClinical outcomesVentricular systolic ejection timeOutpatient transthoracic echocardiogramReduced ejection fractionTertiary referral centerMultivariable logistic regressionHFrEF patientsHF patientsReferral centerTransthoracic echocardiogramAmbulatory patientsHF populationEjection timeEligibility criteriaLogistic regressionPatientsOutcomesAssociationHFpEFEchocardiogram
2016
Markers of Atherosclerosis, Clinical Characteristics, and Treatment Patterns in Heart Failure A Case-Control Study of Middle-Aged Adult Heart Failure Patients in Rural Kenya
Bloomfield GS, DeLong AK, Akwanalo CO, Hogan JW, Carter EJ, Aswa DF, Binanay C, Koech M, Kimaiyo S, Velazquez EJ. Markers of Atherosclerosis, Clinical Characteristics, and Treatment Patterns in Heart Failure A Case-Control Study of Middle-Aged Adult Heart Failure Patients in Rural Kenya. Global Heart 2016, 11: 97-107. PMID: 27102027, PMCID: PMC4843836, DOI: 10.1016/j.gheart.2015.12.014.Peer-Reviewed Original ResearchMeSH KeywordsAgedAnkle Brachial IndexAtherosclerosisBiomarkersCardiomyopathy, DilatedCase-Control StudiesDyslipidemiasEchocardiographyElectrocardiographyFemaleGuideline AdherenceHeart FailureHumansHypertensionKenyaLogistic ModelsMaleMiddle AgedMyocardial IschemiaOdds RatioPractice Guidelines as TopicRisk FactorsRural PopulationConceptsAnkle-brachial indexAtherosclerotic risk factorsIschemic heart failureHeart failureCase-control studyWall motion abnormalitiesRisk factorsMotion abnormalitiesAdult heart failure patientsHuman immunodeficiency virus (HIV) infectionA Case-Control StudyContribution of atherosclerosisImmunodeficiency virus infectionMarker of atherosclerosisHeart failure patientsMultivariable logistic regressionPhysical examination findingsConfidence intervalsRural KenyaIschemic patternLipid testingClinical characteristicsFailure patientsMost patientsExamination findings
2010
Longitudinal and Circumferential Strain Rate, Left Ventricular Remodeling, and Prognosis After Myocardial Infarction
Hung CL, Verma A, Uno H, Shin SH, Bourgoun M, Hassanein AH, McMurray JJ, Velazquez EJ, Kober L, Pfeffer MA, Solomon SD, Investigators V. Longitudinal and Circumferential Strain Rate, Left Ventricular Remodeling, and Prognosis After Myocardial Infarction. Journal Of The American College Of Cardiology 2010, 56: 1812-1822. PMID: 21087709, DOI: 10.1016/j.jacc.2010.06.044.Peer-Reviewed Original ResearchConceptsCircumferential SRMyocardial infarctionHeart failureLongitudinal SRHigh-risk myocardial infarctionVALIANT Echo studyLong-term outcomesMultivariable logistic regressionStandard echocardiographic measuresClinical prognostic valueVentricular contractile performanceCox proportional hazardsParasternal short-axis viewCircumferential strain rateSpeckle-tracking softwareShort-axis viewHospital stayLV dysfunctionSystolic functionEchocardiographic measuresIndependent predictorsClinical outcomesVentricular enlargementPrognostic valueSystolic SR
2008
Relation of Mortality to Failure to Prescribe Beta Blockers Acutely in Patients With Sustained Ventricular Tachycardia and Ventricular Fibrillation Following Acute Myocardial Infarction (from the VALsartan In Acute myocardial iNfarcTion trial [VALIANT] Registry)
Piccini JP, Hranitzky PM, Kilaru R, Rouleau JL, White HD, Aylward PE, Van de Werf F, Solomon SD, Califf RM, Velazquez EJ. Relation of Mortality to Failure to Prescribe Beta Blockers Acutely in Patients With Sustained Ventricular Tachycardia and Ventricular Fibrillation Following Acute Myocardial Infarction (from the VALsartan In Acute myocardial iNfarcTion trial [VALIANT] Registry). The American Journal Of Cardiology 2008, 102: 1427-1432. PMID: 19026290, DOI: 10.1016/j.amjcard.2008.07.033.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAgedClinical Trials as TopicDeath, Sudden, CardiacDrug PrescriptionsFemaleHospital MortalityHumansIncidenceLogistic ModelsMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionPractice Patterns, Physicians'RegistriesRetrospective StudiesRisk AssessmentRisk FactorsTachycardia, VentricularTime FactorsVentricular FibrillationConceptsSustained VT/ventricular fibrillationVT/ventricular fibrillationBeta-blocker therapyAcute myocardial infarctionHeart failureVentricular fibrillationBeta blockersVentricular tachycardiaMyocardial infarctionAcute beta-blocker therapyOral beta blockadeBeta-blocker useHospital mortality rateSustained ventricular arrhythmiasMultivariable logistic regressionSustained ventricular tachycardiaRelation of mortalityBeta blockadeHospital mortalityHospital deathKillip classificationBaseline characteristicsVentricular arrhythmiasEarly mortalityWorse outcomes