2017
Usefulness of Myocardial Annular Velocity Change During Mental Stress to Predict Cardiovascular Outcome in Patients With Coronary Artery Disease (From the Responses of Mental Stress-Induced Myocardial Ischemia to Escitalopram Treatment Trial)
Alenezi F, Brummett BH, Boyle SH, Samad Z, Babyak MA, Alzaeim N, Wilson J, Romano MMD, Sun JL, Ersboll M, O'Connor CM, Velazquez EJ, Jiang W. Usefulness of Myocardial Annular Velocity Change During Mental Stress to Predict Cardiovascular Outcome in Patients With Coronary Artery Disease (From the Responses of Mental Stress-Induced Myocardial Ischemia to Escitalopram Treatment Trial). The American Journal Of Cardiology 2017, 120: 1495-1500. PMID: 28917493, DOI: 10.1016/j.amjcard.2017.07.039.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseStable coronary artery diseaseAdverse cardiovascular outcomesCardiovascular outcomesArtery diseaseNew York Heart Association functional class IMental stress-induced myocardial ischemiaStress-induced myocardial ischemiaNonfatal cardiovascular eventsFunctional class IMental stress testingCox regression modelMS-induced changesCardiovascular eventsCause mortalityUnplanned hospitalizationPrognostic factorsMean ageMyocardial ischemiaSystolic velocityAnnular velocityPatientsMental stressClass IMACE
2014
Platelet aggregation and mental stress induced myocardial ischemia: Results from the Responses of Myocardial Ischemia to Escitalopram Treatment (REMIT) study
Jiang W, Boyle SH, Ortel TL, Samad Z, Velazquez EJ, Harrison RW, Wilson J, Kuhn C, Williams RB, O’Connor C, Becker RC. Platelet aggregation and mental stress induced myocardial ischemia: Results from the Responses of Myocardial Ischemia to Escitalopram Treatment (REMIT) study. American Heart Journal 2014, 169: 496-507.e1. PMID: 25819856, PMCID: PMC4382806, DOI: 10.1016/j.ahj.2014.12.002.Peer-Reviewed Original ResearchConceptsMental stress-induced myocardial ischemiaIschemic heart diseaseSerotonin transporter expressionMyocardial ischemiaPlatelet aggregationPlatelet hyperactivityNormal left ventricular responseStable ischemic heart diseaseStress-induced myocardial ischemiaMental stressTransporter expressionAcute coronary syndromeLeft ventricular responseMental stress testMental stress testingCombination of serotoninEligible patientsCardiovascular eventsCardiovascular prognosisCoronary syndromeVentricular responsePlatelet activityHeart diseaseTreatment studiesIschemia
2011
Responses of mental stress–induced myocardial ischemia to escitalopram treatment: Background, design, and method for the Responses of Mental Stress Induced Myocardial Ischemia to Escitalopram Treatment trial
Jiang W, Velazquez EJ, Samad Z, Kuchibhatla M, Martsberger C, Rogers J, Williams R, Kuhn C, Ortel TL, Becker RC, Pristera N, Krishnan R, O'Connor CM. Responses of mental stress–induced myocardial ischemia to escitalopram treatment: Background, design, and method for the Responses of Mental Stress Induced Myocardial Ischemia to Escitalopram Treatment trial. American Heart Journal 2011, 163: 20-26. PMID: 22172432, PMCID: PMC3254211, DOI: 10.1016/j.ahj.2011.09.018.Peer-Reviewed Original ResearchConceptsMental stress-induced myocardial ischemiaCoronary heart diseaseStable coronary heart diseaseStress-induced myocardial ischemiaMyocardial ischemiaMental Stress–Induced Myocardial IschemiaSelective serotonin reuptake inhibitor (SSRI) treatmentStress testingSerotonin reuptake inhibitor treatmentEjection fraction reductionReuptake inhibitor treatmentMental stress testingPsychometric questionnairesEffects of SSRIsIschemic ST changesInduced Myocardial IschemiaAbnormal wall motionAdult patientsEscitalopram treatmentSSRI treatmentPoor outcomeTreatment trialsPlatelet activityHeart diseaseRisk factors