2009
Quality of life and economic outcomes with surgical ventricular reconstruction in ischemic heart failure: Results from the Surgical Treatment for Ischemic Heart Failure trial
Mark DB, Knight JD, Velazquez EJ, Howlett JG, Spertus JA, Djokovic LT, Harding TM, Rankin GR, Drew LA, Szygula-Jurkiewicz B, Adlbrecht C, Anstrom KJ, Investigators F. Quality of life and economic outcomes with surgical ventricular reconstruction in ischemic heart failure: Results from the Surgical Treatment for Ischemic Heart Failure trial. American Heart Journal 2009, 157: 837-844.e3. PMID: 19376309, PMCID: PMC2694042, DOI: 10.1016/j.ahj.2009.03.008.Peer-Reviewed Original ResearchMeSH KeywordsAgedCoronary Artery BypassFemaleFollow-Up StudiesHealth Care CostsHeart FailureHeart VentriclesHumansMaleMiddle AgedMyocardial IschemiaPlastic Surgery ProceduresQuality of LifeRetrospective StudiesStroke VolumeSurveys and QuestionnairesTreatment OutcomeUnited StatesVentricular Function, LeftConceptsCoronary artery bypass graft surgerySurgical ventricular reconstructionIschemic heart failureQuality of lifeHeart failureVentricular reconstructionQOL measuresIschemic Heart Failure (STICH) trialKansas City Cardiomyopathy QuestionnaireTotal index hospitalization costsArtery bypass graft surgeryLeft ventricular ejection fractionBetter QOLIndex hospitalization costsBypass graft surgeryHeart failure symptomsHeart Failure TrialVentricular ejection fractionLeft ventricular functionHealth care costsTreatment-related differencesGraft surgeryEjection fractionSurgical treatmentVentricular function
2008
Emerging Role of Myocardial Perfusion Imaging to Evaluate Patients for Cardiac Resynchronization Therapy††Conflicts of interest: Dr. Garcia has an ownership interest in and serves as a consultant and advisory board member for Syntermed, Inc., Atlanta, Georgia. Dr. Garcia also receives royalties from the sale of clinical software that was used as part of this research. Dr. Borges-Neto and Dr. Trimble have received research support from the Duke-Medtronic Strategic Alliance, which funded some of the studies reviewed in this report.
Trimble MA, Borges-Neto S, Velazquez EJ, Chen J, Shaw LK, Pagnanelli R, Garcia EV, Iskandrian AE. Emerging Role of Myocardial Perfusion Imaging to Evaluate Patients for Cardiac Resynchronization Therapy††Conflicts of interest: Dr. Garcia has an ownership interest in and serves as a consultant and advisory board member for Syntermed, Inc., Atlanta, Georgia. Dr. Garcia also receives royalties from the sale of clinical software that was used as part of this research. Dr. Borges-Neto and Dr. Trimble have received research support from the Duke-Medtronic Strategic Alliance, which funded some of the studies reviewed in this report. The American Journal Of Cardiology 2008, 102: 211-217. PMID: 18602524, DOI: 10.1016/j.amjcard.2008.03.043.Peer-Reviewed Original ResearchConceptsCardiac resynchronization therapyMechanical dyssynchronyElectrical dyssynchronyMyocardial perfusionSignificant heart failure symptomsTomographic myocardial perfusion imagingLV functional improvementHeart failure symptomsLV systolic dysfunctionSevere LV dysfunctionSelection of patientsManagement of patientsLV mechanical dyssynchronyLeft ventricular dyssynchronyMyocardial perfusion imagingCurrent selection criteriaLV dysfunctionSystolic dysfunctionEchocardiographic measuresResynchronization therapyVentricular dyssynchronyCardiac resynchronizationClinical statusLV remodelingFailure symptoms
2004
Clinical characteristics and referral pattern of patients with left ventricular dysfunction and significant coronary artery disease undergoing radionuclide imaging
Bourque JM, Velazquez EJ, Borges-Neto S, Shaw LK, Whellan DJ, O'Connor C. Clinical characteristics and referral pattern of patients with left ventricular dysfunction and significant coronary artery disease undergoing radionuclide imaging. Journal Of Nuclear Cardiology 2004, 11: 118-125. PMID: 15052242, DOI: 10.1016/j.nuclcard.2003.09.005.Peer-Reviewed Original ResearchConceptsSignificant coronary artery diseaseCoronary artery diseaseLeft ventricular dysfunctionReferral patternsLV dysfunctionVentricular dysfunctionArtery diseaseMyocardial infarctionObservational studyMyocardial perfusion imaging resultsCharlson Comorbidity IndexHeart failure symptomsCongestive heart failureLogistic regression modelingNuclear perfusionCohort patientsComorbidity indexPrior revascularizationBaseline characteristicsCatheterization resultsClinical characteristicsCardiac revascularizationEjection fractionHeart failurePerfusion testing
2002
Comparison of coronary artery bypass grafting versus medical therapy on long-term outcome in patients with ischemic cardiomyopathy (a 25-year experience from the Duke Cardiovascular Disease Databank)
O’Connor C, Velazquez EJ, Gardner LH, Smith PK, Newman MF, Landolfo KP, Lee KL, Califf RM, Jones RH. Comparison of coronary artery bypass grafting versus medical therapy on long-term outcome in patients with ischemic cardiomyopathy (a 25-year experience from the Duke Cardiovascular Disease Databank). The American Journal Of Cardiology 2002, 90: 101-107. PMID: 12106836, DOI: 10.1016/s0002-9149(02)02429-3.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiac CatheterizationComorbidityCoronary AngiographyCoronary Artery BypassCoronary Artery DiseaseDisease-Free SurvivalFemaleFollow-Up StudiesHeart FailureHumansMaleMiddle AgedOutcome and Process Assessment, Health CareSurvival AnalysisTimeTreatment OutcomeVentricular Dysfunction, LeftConceptsCoronary artery bypass surgeryLong-term outcomesMedical therapyCoronary diseaseIschemic cardiomyopathyNew York Heart Association class IILeft ventricular ejection fractionCox proportional hazards modelDuke University Medical CenterDays of catheterizationInitial cardiac catheterizationMedical therapy armObservational treatment comparisonsCoronary artery bypassHeart failure symptomsMedical therapy groupVentricular systolic dysfunctionArtery bypass surgeryVentricular ejection fractionCoronary artery diseaseEpicardial coronary vesselsProportional hazards modelUniversity Medical CenterCABG groupTherapy arm