2017
Race and Sex Differences in QRS Interval and Associated Outcome Among Patients with Left Ventricular Systolic Dysfunction
Randolph TC, Broderick S, Shaw LK, Chiswell K, Mentz RJ, Kutyifa V, Velazquez EJ, Gilliam FR, Thomas KL. Race and Sex Differences in QRS Interval and Associated Outcome Among Patients with Left Ventricular Systolic Dysfunction. Journal Of The American Heart Association 2017, 6: e004381. PMID: 28320746, PMCID: PMC5523998, DOI: 10.1161/jaha.116.004381.Peer-Reviewed Original ResearchConceptsQRS durationBundle branch blockWhite patientsHeart failureBlack patientsBranch blockNon-left bundle branch block morphologyLeft ventricular systolic dysfunctionMultivariable Cox regression modelsBundle branch block morphologyLeft bundle branch blockMedian QRS durationVentricular systolic dysfunctionHeart failure patientsVentricular ejection fractionShorter QRS durationCox regression modelRisk of mortalityDuke University HospitalBlack individualsSex differencesCause mortalitySystolic dysfunctionCoronary angiographyEjection fractionComparison of Clinical Characteristics and Outcomes of Patients With Versus Without Diabetes Mellitus and With Versus Without Angina Pectoris (from the Duke Databank for Cardiovascular Disease)
Banks A, Broderick S, Chiswell K, Shaw L, Devore A, Fiuzat M, O'Connor C, Felker GM, Velazquez E, Mentz R. Comparison of Clinical Characteristics and Outcomes of Patients With Versus Without Diabetes Mellitus and With Versus Without Angina Pectoris (from the Duke Databank for Cardiovascular Disease). The American Journal Of Cardiology 2017, 119: 1703-1709. PMID: 28395884, DOI: 10.1016/j.amjcard.2017.02.053.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseAngina pectorisDiabetes mellitusDM statusCause mortalityMultivariable Cox regressionOutcomes of patientsDifferent prognostic implicationsSeverity of diseaseAP statusCV hospitalizationClinical characteristicsArtery diseaseCoronary angiographyDM patientsClinical outcomesCox regressionPrognostic implicationsPrognostic utilityRevascularizationSimilar riskPatientsRisk adjustmentMortalityPectoris
2014
Clinical outcome as a function of the PR-interval—there is virtue in moderation: data from the Duke Databank for cardiovascular disease
Holmqvist F, Thomas KL, Broderick S, Ersbøll M, Singh D, Chiswell K, Shaw LK, Hegland DD, Velazquez EJ, Daubert JP. Clinical outcome as a function of the PR-interval—there is virtue in moderation: data from the Duke Databank for cardiovascular disease. EP Europace 2014, 17: 978-985. PMID: 25164430, DOI: 10.1093/europace/euu211.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseHeart diseaseDuke University Medical CenterMajor cardiovascular outcomesMajor cardiovascular eventsNative coronary arteriesUniversity Medical CenterPR interval durationCV eventsCardiovascular eventsCardiovascular outcomesCause mortalityCoronary angiographyDuke DatabankClinical outcomesAtrial fibrillationPoor outcomeCoronary arterySignificant stenosisSinus rhythmCardiovascular diseaseMedical CenterHigh riskPatientsRelevant covariates
2009
Usefulness of the Duke Sudden Cardiac Death Risk Score for Predicting Sudden Cardiac Death in Patients With Angiographic (>75% Narrowing) Coronary Artery Disease
Atwater BD, Thompson VP, Vest RN, Shaw LK, Mazzei WR, Al-Khatib SM, Hranitzky PM, Bahnson TD, Velazquez EJ, Califf RM, Lee KL, Roe MT. Usefulness of the Duke Sudden Cardiac Death Risk Score for Predicting Sudden Cardiac Death in Patients With Angiographic (>75% Narrowing) Coronary Artery Disease. The American Journal Of Cardiology 2009, 104: 1624-1630. PMID: 19962465, DOI: 10.1016/j.amjcard.2009.07.042.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseSCD risk scoreRisk of SCDArtery diseaseRisk scoreSCD riskDepressed left ventricular ejection fractionAngiographic coronary artery diseasePredicting Sudden Cardiac DeathLeft ventricular ejection fractionNative coronary artery stenosisCox proportional hazards modelVentricular ejection fractionSudden cardiac deathCoronary artery stenosisDeath risk scorePatient characteristic variablesRisk prediction toolsDiseased coronary arteriesProportional hazards modelAngiographic characteristicsRisk patientsCardiac deathCoronary angiographyDiabetes mellitus
2002
Revascularization improves survival in ischemic cardiomyopathy regardless of electrocardiographic criteria for prior small-to-medium myocardial infarcts
Shah BR, Velazquez E, Shaw LK, Bart B, O'Connor C, Wagner GS. Revascularization improves survival in ischemic cardiomyopathy regardless of electrocardiographic criteria for prior small-to-medium myocardial infarcts. American Heart Journal 2002, 143: 111-117. PMID: 11773920, DOI: 10.1067/mhj.2002.119996.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionIschemic cardiomyopathyMyocardial infarctionQRS scoreTreatment groupsSelvester QRS scoring systemVentricular ejection fractionMajor coronary arteriesPrevious myocardial infarctionAcute myocardial infarctionQRS scoring systemSignificant treatment differencesElectrocardiographic evidenceCoronary angiographyEjection fractionIndependent predictorsInfarct sizeCoronary arteryHibernating myocardiumRevascularizationDecreased functionBetter survivalMyocardial infarctElectrocardiographic criteriaPatients