2021
Association Between Preexisting Versus Newly Identified Atrial Fibrillation and Outcomes of Patients With Acute Pulmonary Embolism
Bikdeli B, Jiménez D, del Toro J, Piazza G, Rivas A, Fernández‐Reyes J, Sampériz Á, Otero R, Suriñach J, Siniscalchi C, Martín‐Guerra J, Castro J, Muriel A, Lip G, Goldhaber S, Monreal M, Monreal M, Prandoni P, Brenner B, Farge‐Bancel D, Barba R, Di Micco P, Bertoletti L, Schellong S, Tzoran I, Reis A, Bosevski M, Bounameaux H, Malý R, Verhamme P, Caprini J, Bui H, Adarraga M, Agud M, Aibar J, Aibar M, Amado C, Arcelus J, Baeza C, Ballaz A, Barba R, Barbagelata C, Barrón M, Barrón‐Andrés B, Blanco‐Molina Á, Botella E, Camon A, Cañas I, Casado I, Castro J, Chasco L, Criado J, de Ancos C, de Miguel J, del Toro J, Demelo‐Rodríguez P, Díaz‐Peromingo J, Di Campli M, Díez‐Sierra J, Domínguez I, Escribano J, Falgá C, Farfán‐Sedano A, Fernández‐Capitán C, Fernández‐Reyes J, Fidalgo M, Flores K, Font C, Font L, Francisco I, Gabara C, Galeano‐Valle F, Galindo D, García M, García‐Bragado F, de Herreros M, García‐Hernáez R, García‐Mullor M, García‐Raso A, Gavín‐Sebastián O, Gil‐Díaz A, Gómez‐Cuervo C, Grau E, Guirado L, Gutiérrez J, Hernández‐Blasco L, Hernando E, Herreros M, Jara‐Palomares L, Jaras M, Jiménez D, Jiménez R, Joya M, León J, Lima J, Llamas P, Lobo J, López‐Jiménez L, López‐Miguel P, López‐Núñez J, López‐Reyes R, López‐Ruiz A, López‐Sáez J, Lorenzo A, Madridano O, Maestre A, Marchena P, del Pozo M, Martín‐Guerra J, Martín‐Martos F, Mella C, Mellado M, Mercado M, Moisés J, Monreal M, del Valle Morales M, Muñoz‐Blanco A, Muñoz‐Rivas N, Navas M, Nieto J, Núñez‐Fernández M, Obispo B, Olid M, Olivares M, Orcastegui J, Ortega‐Michel C, Osorio J, Otalora S, Otero R, Parra P, Parra V, Pedrajas J, Pellejero G, Porras J, Portillo J, Riera‐Mestre A, Rivas A, Rivera‐Civico F, Rodríguez‐Chiaradía D, Rodríguez‐Cobo A, Rodríguez‐Matute C, Rogado J, Roig S, Rosa V, Ruiz‐Artacho P, Ruiz‐Giménez N, Ruiz‐Ruiz J, Ruiz‐Sada P, Salgueiro G, Sánchez‐Martínez R, Sánchez‐Muñoz‐Torrero J, Sancho T, Sirisi M, Soler S, Suriñach J, Tirado R, Torres M, Tolosa C, Trujillo‐Santos J, Uresandi F, Valero B, Valle R, Vela J, Vidal G, Villares P, Zamora C, Gutiérrez P, Vázquez F, Engelen M, Vanassche T, Verhamme P, Hirmerova J, Malý R, Salgado E, Abdallah N, Bertoletti L, Bura‐Riviere A, Crichi B, Debourdeau P, Olivier E, Falvo N, Farge‐Bancel D, Galliazzo S, Helfer H, Mahé I, Moustafa F, Poenou G, Schellong S, Braester A, Brenner B, Tzoran I, Bilora F, Bucherini E, Ciammaichella M, Di Micco P, Imbalzano E, Maida R, Mastroiacovo D, Pace F, Pesavento R, Pomero F, Prandoni P, Quintavalla R, Rocci A, Romualdi R, Siniscalchi C, Tufano A, Visonà A, Zalunardo B, Gibietis V, Kigitovica D, Skride A, Fonseca S, Martins F, Meireles J, Bosevski M, Bounameaux H, Mazzolai L, Bikdeli B, Caprini J, Tafur A, Ochoa‐Chaar C, Weinberg I, Wilkins H, Bui H. Association Between Preexisting Versus Newly Identified Atrial Fibrillation and Outcomes of Patients With Acute Pulmonary Embolism. Journal Of The American Heart Association 2021, 10: e021467. PMID: 34459215, PMCID: PMC8649245, DOI: 10.1161/jaha.121.021467.Peer-Reviewed Original ResearchConceptsAcute pulmonary embolismIncident atrial fibrillationPulmonary embolismAtrial fibrillationAcute symptomatic pulmonary embolismNew incident atrial fibrillationTiming of AFNew atrial fibrillationOutcomes of patientsSymptomatic pulmonary embolismAdverse clinical outcomesBackground Atrial fibrillationAF onsetCause mortalityMultivariable adjustmentIschemic strokeClinical outcomesMultivariable analysisAdverse outcomesPatientsMortalityStrokeEmbolismOutcomesFibrillation
2020
Lower Extremity Revascularization for Chronic Limb-Threatening Ischemia among Patients at the Extremes of Age
Kim TI, Aboian E, Fischer U, Zhang Y, Guzman RJ, Ochoa Chaar CI. Lower Extremity Revascularization for Chronic Limb-Threatening Ischemia among Patients at the Extremes of Age. Annals Of Vascular Surgery 2020, 72: 517-528. PMID: 32927042, DOI: 10.1016/j.avsg.2020.08.135.Peer-Reviewed Original ResearchMeSH KeywordsAge of OnsetAgedAged, 80 and overAgingAmputation, SurgicalChronic DiseaseDatabases, FactualEndovascular ProceduresFemaleHumansIschemiaLimb SalvageLower ExtremityMaleMiddle AgedPeripheral Arterial DiseaseRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeVascular Surgical ProceduresConceptsChronic limb-threatening ischemiaLower extremity revascularizationExtremes of ageRisk factor profileMajor amputationPatients 51Extremity revascularizationFactor profileDistinct risk factor profilesAge groupsChronic limb threatening ischemiaLimb threatening ischemiaLimb-threatening ischemiaMajor amputation ratePeripheral artery diseaseGroup of patientsInsulin-dependent diabetesExtreme age groupsSuprainguinal bypassAmputation rateElderly patientsInfrainguinal bypassActive smokersArtery diseaseMultivariable analysisTrends and outcomes of thoracic endovascular aortic repair with open concomitant cervical debranching
Bellamkonda KS, Yousef S, Nassiri N, Dardik A, Guzman RJ, Geirsson A, Ochoa Chaar CI. Trends and outcomes of thoracic endovascular aortic repair with open concomitant cervical debranching. Journal Of Vascular Surgery 2020, 73: 1205-1212.e3. PMID: 32861861, DOI: 10.1016/j.jvs.2020.07.103.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAorta, ThoracicAortic DiseasesBlood Vessel Prosthesis ImplantationCarotid ArteriesDatabases, FactualEndovascular ProceduresFemaleHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesRisk AssessmentRisk FactorsSubclavian ArteryTime FactorsTreatment OutcomeYoung AdultConceptsCarotid-carotid bypassEndovascular aortic repairCervical debranchingPerioperative outcomesAortic repairAortic pathologyMultivariable analysisThoracic endovascular aortic repairSurgeons National Surgical Quality Improvement Program filesCarotid-subclavian bypassDependent functional statusOpen surgical debranchingUse of TEVARLonger hospital stayCurrent Procedural Terminology codesUrgency of surgeryComplex aortic pathologiesThoracic aortic pathologyCommon surgical procedureProcedural Terminology codesSignificant differencesNumber of bypassesAdvanced endovascular technologySurgical debranchingDebranching proceduresDiscrepancy in Outcomes after Revascularization for Chronic Limb-Threatening Ischemia Warrants Separate Reporting of Rest Pain and Tissue Loss
Brahmandam A, Gholitabar N, Cardella J, Nassiri N, Dardik A, Georgi M, Ochoa Chaar CI. Discrepancy in Outcomes after Revascularization for Chronic Limb-Threatening Ischemia Warrants Separate Reporting of Rest Pain and Tissue Loss. Annals Of Vascular Surgery 2020, 70: 237-244. PMID: 32659417, DOI: 10.1016/j.avsg.2020.06.057.Peer-Reviewed Original ResearchMeSH KeywordsAgedAmputation, SurgicalBenchmarkingChronic DiseaseComorbidityDatabases, FactualFemaleHospital MortalityHumansInpatientsIntermittent ClaudicationIschemiaMalePeripheral Arterial DiseaseQuality Indicators, Health CareRetrospective StudiesRisk AssessmentRisk FactorsTreatment OutcomeUnited StatesVascular Surgical ProceduresConceptsLower extremity revascularizationCharlson Comorbidity IndexRest painMajor amputationInpatient mortalityTissue lossEndovascular lower extremity revascularizationWorse short-term outcomesShort-term outcomesNational Inpatient SampleLength of stayMultivariable regression analysisComorbidity indexExtremity revascularizationPatient characteristicsMultivariable analysisInpatient SampleHigh comorbidityMean costPatientsAmputationMortalityTL groupOutcomesRevascularizationThe Use of Embolic Protection Devices during Lower Extremity Peripheral Vascular Interventions
Ochoa Chaar CI, Kim TI, Shebl FM, Dardik A. The Use of Embolic Protection Devices during Lower Extremity Peripheral Vascular Interventions. Annals Of Vascular Surgery 2020, 69: 9-16. PMID: 32554197, DOI: 10.1016/j.avsg.2020.06.014.Peer-Reviewed Original ResearchConceptsPeripheral vascular interventionsEmbolic protection devicesDistal embolizationMultivariable analysisFluoroscopy timeVascular interventionsEPD useLower extremity peripheral vascular interventionsUse of EPDPropensity-matched control groupChronic obstructive pulmonary diseaseSignificant differencesVascular Study GroupCharacteristics of patientsObstructive pulmonary diseaseCoronary artery diseaseNew England databaseSuperficial femoral arteryExcisional atherectomyArtery diseaseCommon indicationPropensity matchingPulmonary diseaseEndovascular treatmentFemoral arteryThe Reintervention Index: A New Outcome Measure for Comparative Effectiveness of Lower Extremity Revascularization
Ochoa Chaar CI, Gholitabar N, DeTrani M, Jorshery S, Zhuo H, Zhang Y, Dardik A. The Reintervention Index: A New Outcome Measure for Comparative Effectiveness of Lower Extremity Revascularization. Annals Of Vascular Surgery 2020, 69: 52-61. PMID: 32474144, DOI: 10.1016/j.avsg.2020.05.040.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAmputation, SurgicalComparative Effectiveness ResearchEndarterectomyEndovascular ProceduresFemaleHumansLimb SalvageLower ExtremityMaleMiddle AgedPeripheral Arterial DiseasePostoperative ComplicationsRetreatmentRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeVascular GraftingConceptsOpen lower extremity revascularizationLower extremity revascularizationPeripheral artery diseaseEndovascular groupExtremity revascularizationOutcome measuresEndovascular lower extremity revascularizationFrequency of reinterventionsTertiary care centerCurrent outcome measuresNew outcome measureType of procedureCardiovascular comorbiditiesMajor amputationEndovascular revascularizationReintervention ratePatient characteristicsArtery diseaseConsecutive patientsMultivariable analysisRetrospective reviewOpen groupCare centerEndovascular proceduresReintervention
2019
Statin therapy associated with improved thrombus resolution in patients with deep vein thrombosis
Hsu C, Brahmandam A, Brownson KE, Huynh N, Reynolds J, Lee AI, Fares WH, Ochoa Chaar CI. Statin therapy associated with improved thrombus resolution in patients with deep vein thrombosis. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2019, 7: 169-175.e4. PMID: 30660579, DOI: 10.1016/j.jvsv.2018.10.020.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnticoagulantsElectronic Health RecordsFemaleHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMiddle AgedPlatelet Aggregation InhibitorsPulmonary EmbolismRecurrenceRetrospective StudiesRisk AssessmentRisk FactorsThrombolytic TherapyTime FactorsTreatment OutcomeVena Cava FiltersVenous ThromboembolismVenous ThrombosisConceptsDeep venous thrombosisExtent of DVTStatin therapyThrombus resolutionPulmonary embolismVenous thromboembolismVTE recurrenceAntiplatelet therapyMultivariable analysisRisk factorsRecurrence of DVTLower extremity deep venous thrombosisHigh-risk pulmonary embolismPrior deep venous thrombosisProvoked deep venous thrombosisProximal deep venous thrombosisInferior vena cava filter placementExtremity deep venous thrombosisVena cava filter placementDuration of anticoagulationAssociation of statinConsecutive adult patientsDirect oral anticoagulantsManifestations of atherosclerosisCava filter placement