Yale Researchers Track the Lifespan and Myriad Functions of mRNA
New research sheds light on how mRNAs are born and how they regulate production of proteins inside of our cells once they reach maturity. The findings have implications not only for achieving effective doses for new vaccines, but for helping determine the biological roots of many cancers and diseases.Source: Hathaway
Newly Recruited Scientists Bring Innovative Imaging Technology to YSM
Enhanced FIB-SEM has enabled discoveries in tissue biology, cell biology, and the connectome—the system of neural pathways in the brain. Recently, it enabled an open-access high-resolution 3D atlas of whole cells and tissues, from cancer and immune cells to mouse pancreatic islets and Drosophila neural tissues.
You’re Pregnant: Is It Safe To Get a COVID-19 Vaccine?
A new study of more than 46,000 pregnant women shows that COVID-19 vaccination does not increase the risk of delivering a premature baby or of having a baby born smaller than expected—both of which are linked to higher chances of infant death and disability.Source: Yale Medicine
Nasal Vaccination May Protect Against Respiratory Viruses Better Than Injected Vaccines
Akiko Iwasaki, PhD, discusses her lab's finding that intranasal vaccinations, by triggering immune properties of mucosal membranes, may offer better protection against respiratory viruses than injected vaccines.
Nakasone Prize Won By Arthur Horwich, MD
The HFSP Nakasone Award is designated for scientists whose work has led to significant breakthroughs in the life sciences. It was named after Japan’s former Prime Minister Yasuhiro Nakasone, who believed in the importance of international collaboration for the advancement of science.
Severe Breakthrough COVID-19 Cases Drive Urgency of Boosters
Breakthrough SARS-CoV-2 infections tend to be mild, but new Yale research shows that more older adults have developed severe breakthrough cases during the Delta variant phase of the pandemic, particularly after a longer period of time had elapsed since their last vaccination.Source: YaleNews
Viruses and Cancer: A 45-year Legacy of Research and Collaboration
When Daniel DiMaio, MD, PhD, Joan Steitz, PhD, and I. George Miller, MD, pooled their talents to put together a 400-page application to the NIH back in 1975 they never imagined it would became the longest-running program project grant at Yale, and the third longest at the NIH.
Vaccine Clinic Offers Choice and Reassurance to New Haven Children
Corinne Scott, 8, and Chidera Ogbuagu, 10, lined up at a vaccine clinic at Elm City Montessori School in New Haven on November 6th. Helping children like Chidera and Corinne feel good about getting vaccinated is a key part of the vaccine effort’s broader success.
Novel Lyme Vaccine Shows Promise
Instead of triggering an immune response against a particular pathogen, the new vaccine prompts a quick response in the skin to components of tick saliva, limiting the time ticks have to feed and infect the host, a study shows. The vaccine is delivered by the same mRNA technology that has proved so effective against COVID-19.Source: YaleNews
New Grant Supports Early-career Faculty Facing Pandemic-related Challenges
COVID-19 introduced more obstacles to an already challenging career path. As the pandemic forced labs to shut down across campus and children to transition to at-home learning, early-career faculty faced a growing number of new stressors.
$13 Million Grant to Study Malignant Brain Tumors Awarded to YSPH Researcher and Colleagues
A team of scientists led by researchers at the Yale School of Public Health has received a $13 million grant to investigate the molecular evolution of lower grade gliomas, slow growing but malignant brain tumors that primarily affect young adults.