To Break Through Bacteria’s Protective Shield, Target the Shield-maker
Yale researchers have now uncovered a key part of the process that generates an additional protective layer of the cell wall of bacteria, a finding that may help reveal vulnerabilities that could be targeted by new antibiotics.Source: YaleNews
Yale Professors Join Universiti Malaya Colleagues for Implementation Science Boot Camp
Faculty members from the Yale School of Public Health (YSPH) and Yale School of Medicine (YSM) recently joined an interdisciplinary group of students and researchers in Kuala Lumpur for a summer boot camp on implementation science.
To Better Understand the Brain, Look at the Bigger Picture
Researchers evaluated various approaches to fMRI and found that zooming out and taking a wider field of view captures additional relevant information that a narrow focus leaves out, offering greater understanding of neural interplay.Source: YaleNews
New Online Training for Mental Health Providers Benefits LGBTQ Community
Mental health providers can learn to deliver evidence-based LGBTQ-affirmative cognitive therapy through low-cost online training, which would help deliver more evidence-based mental health care to LGBTQ people and support its implementation across practice settings, according to a new study by Yale School of Public Health (YSPH) researchers.
Two Heart Medications Tied to Greater Heart Attack Risk During Very Hot Weather
A new Yale study found that, among people suffering non-fatal heart attacks associated with hot weather, an outsize portion were taking beta-blockers or antiplatelet medication. The study doesn’t prove that these medications caused the heart attacks, nor that they make people more vulnerable to heart attack. Although it’s possible that they did increase the risk of heart attacks triggered by hot weather, it’s also possible that patients’ underlying heart disease explains both the prescriptions and the higher susceptibility to heart attack during hot weather.
Pre-surgical Immunotherapy Benefits Are Independent of Race in Women With Triple-Negative Breast Cancer
Despite a higher prevalence of triple-negative breast cancer (TNBC) among Black women compared to White women, Black women are underrepresented in TNBC clinical trials, particularly those involving novel immunotherapies. In a study published today in Clinical Cancer Research, researchers at Yale Cancer Center used data from a previous study showing that the combination of durvalumab and neoadjuvant chemotherapy was well tolerated and resulted in high pathologic complete response (pCR) rate in women with non-metastatic TNBC before surgery to recruit another group of racially diverse patients to see if the results were the same. Durvalumab is an immunotherapeutic that targets the PD-1/PD-L1 immune checkpoint pathway.
Study: Vaccines and Booster Shots Are Key to Controlling Spread of COVID Variants
A new study by researchers at the Yale School of Public Health emphasizes the continuing importance of vaccines and booster shots at the individual and population level in controlling infections from highly contagious new variants of COVID-19.
Climate Change and Energy Insecurity Are Impacting Connecticut Residents’ Health
The environmental impacts of climate change and a complex and often inefficient network of energy assistance programs are negatively affecting the health and well-being of Connecticut residents already burdened by the state’s soaring utility costs, according to a new report.
Helping Students Build Strong Foundations in Ethical Global Health Work
The Global Health Ethics Program (GHEP), which is part of the Yale Institute for Global Health, helps students prepare for potential ethical challenges before they conduct research or clinical projects abroad.Source: YaleNews