The Departments of Anesthesiology and Neurology Host: “Perivascular Spaces in the Brain & Contributions to Pathology of Cerebral Small Vessel Disease” on March 24
The purpose of this Yale mini-symposium is to highlight the huge unmet clinical need to understand the pathophysiology of small vessel disease to inform future therapeutic efforts to reduce the burden of this illness due to cognitive impairment and dementia. In particular the cellular and molecular mechanisms that underlie diffuse white matter disease and small vessel disease in the brain, the relationships between them, and how they may contribute to cognitive impairment and dementia.
Weighing Cognitive Decline After Prostate Cancer Treatment
The October 17, 2019 Department of Internal Medicine’s inaugural The Second Century of Women at Yale: Emerging Leaders in Internal Medicine Medical Grand Rounds, “Cognitive Side Effects of Cancer Therapy,” was presented by Herta H. Chao, MD, PhD, associate professor of medicine (medical oncology).
Yale Receives Funding to Study Myasthenia Gravis
The National Institutes of Health through the Rare Diseases Clinical Research Consortia has awarded a research team from Yale University, George Washington University, and Duke University $7.8 million to establish a rare disease network for myasthenia gravis.
Yale Faculty Pioneer Development and Testing of Portable MRI Device
Yale researchers have agreed to develop, deploy, and test a new portable MRI scanner, a device its developer hopes will cost a fraction of that of traditional MRIs and make the new imaging technology available in clinics in the U.S. and around the world.
Brain Hemorrhage Surgery Boosts Survival, but Disability Risk Still High
While patients who undergo surgery for intracerebral hemorrhage (ICH) survive at higher rates than those who do not receive surgery, they are also at high risk of significant disability, according to a new Yale-led study published in the journal JAMA.
Yale Department of Neurology Receives Grant for Stroke Study
Yale’s Department of Neurology is one of seven medical institutions awarded $4 million from the National Institutes of Health to assess acute ischemic stroke treatments in rodent models. As a part of the Stroke Preclinical Assessment Network (SPAN), participating institutions will work together to increase the rigor surrounding testing for ischemic brain injury, taking a look at six neuroprotective therapies to improve outcomes after stroke.
Yale Designated as Parkinson’s Foundation Research Center
Yale School of Medicine been designated as one of four Parkinson’s Foundation Research Centers, the foundation announced July 30. The Parkinson’s Foundation awarded each center $2 million over five years “to drive innovative research developments and advance Parkinson’s disease research towards a cure.”
Parkinson’s Disease Study Identifies Possible New Treatment Target
Treatments for Parkinson’s disease have most recently focused on increasing dopamine, a chemical messenger in the brain that affects reward-based behaviors and motivation, as well as movement. A new study by Yale researchers challenges long-held assumptions about dopamine’s sole role in this disorder.
HIV DNA That Lingers in Spinal Fluid May Be Linked to Cognitive Problems
Even in patients who receive long-term anti-retroviral treatment, cells containing HIV remain in the cerebrospinal fluid of half of those treated for the disease, and those individuals are more likely to experience cognitive deficits than those without cells that have HIV, a new study has found.
Department of Neurology Receives Major Grant to Evaluate Blood Thinners and Stroke Prevention
Yale School of Medicine has received a 5-year, $20 million grant from the National Institute of Neurological Disorders and Stroke (NINDS) to administer a Phase III trial measuring the effectiveness of using a blood thinner to prevent new strokes in patients who suffered brain hemorrhages and have atrial fibrillation, or irregular heartbeat.
Yale IBIO investigators link tolerance defects to pathogenic autoantibody production
A team led by IBIO faculty members, Eric Meffre and Kevin O’Connor, explored both B cell tolerance and the origins of pathogenic autoantibodies in neuromyelitis optica (NMO), a severe autoimmune neurological disease that primarily affects young women.
Yale PET Scientists receive Early Career Investigator travel awards for 2019 BRAIN PET Meeting
Takuya Toyonaga, Xiaotian Fang, and Pragalath Sadasivam were awarded Early Career Investigator travel awards by the International Society for Cerebral Blood Flow & Metabolism (ISCBFM) to attend the BRAIN & BRAIN PET conference in Yokohama, Japan.
Behavioral disorders in kids with autism linked to reduced brain connectivity
More than a quarter of children with autism spectrum disorder are also diagnosed with disruptive behavior disorders. For the first time, Yale researchers have identified a possible biological cause: a key mechanism that regulates emotion functions differently in the brains of the children who exhibit disruptive behavior.
Rakic awarded 2019 Connecticut Medal of Science
The State of Connecticut and Connecticut Academy of Science and Engineering have awarded the 2019 Connecticut Medal of Science to Pasko Rakic, MD, PhD, Dorys McConnell Duberg Professor of Neuroscience and Professor of Neurology at Yale School of Medicine.
Alzheimer's Disease Research Center will hold a research day on Feb. 12
The Alzheimer's Disease Research Center will be hosting a Research Day, which will include a series of lectures on current research studies on Alzheimer's Disease. The following Investigators will be presenting: Christopher van Dyck, MD; Jason Cai, PhD; Amy Arnsten, PhD; Morgan Levine, PhD; Nenad Sestan, MD,PhD; In Hyun Park, PhD; and Flora Vaccarino, MD.