Parental Birth Abnormalities and Offspring’s Autism Linked
In a study of medical registry records of nearly 400,000 parent-child pairs from Denmark, a Yale School of Public Health study found that parents who themselves born very prematurely are nearly twice as likely to have children with autism spectrum disorder.
Jawless Lamprey Takes a Bite out of Oncogene Evolution
By carefully tracing the evolution of a select number of cancer-causing genes in a variety of species, the researchers evaluated which animals are — and are not — effective in gauging how an analogue of those genes in humans can lead to cancer. What they found is surprising: jawless fish such as lampreys share significant similarities in these certain genes compared to humans, while fruit flies do not.
Major Gift Will Support an Innovative Brain Research Collaboration
The Swiss-based NOMIS Foundation is making a large five-year award for research into what makes the human brain unique. The research will be a collaboration between the laboratories of James P. Noonan, PhD, associate professor of genetics and of neuroscience at Yale School of Medicine, and Franck Polleux, PhD, professor of neuroscience at Columbia University and a member of that school’s Zuckerman Institute. Their combined mission is to understand the brain and mind.
Geneticist Sidi Chen Receives Large Award Which Will Further His Breast Cancer Work
This Department of Defense award goes to the “best and brightest in their fields,” and recognizes “creative and innovative individuals.” Investigators are chosen for their ability “to go beyond conventional thinking” in their respective areas of expertise.
Major Gift Will Endow a Program Devoted to a Fuller Understanding of How the Human Brain Works
The Thomas Kingsley Lawrence ’19 Program in Brain Research will take a multifaceted approach to understanding the higher-order functionality of the human brain and related areas. It is hoped that with the knowledge gained, novel prevention strategies, diagnostics, and therapeutics to reduce the incidence, prevalence, and recurrence of psychiatric disorders will be possible.
Editing mosquito’s gene wards off malaria and halts reproduction
Scientists have looked for immune system factors that might help mosquitoes ward off pathogens such as malarial parasites and indirectly protect humans from infection. Yale researchers found one by editing a single gene, which turns out to be crucial for female reproduction.
Schechner Memorial Lecture, Hosted by Department of Dermatology, to Be Given by Valentina Greco, PhD, on Oct. 30
Valentina Greco, PhD, Carolyn Walch Slayman Professor of Genetics, will speak about "Principles of Skin Epithelial Tolerance Discovered by Live Imaging" on October 30 at 10 a.m., in the Fitkin Amphitheatre.
Yale Scientists Help Immune System Find Hidden Cancer Cells
Cancer cells are masters at avoiding detection, but a new system developed by Yale Cancer Center scientists can make them stand out from the crowd and help the immune system spot and eliminate tumors that other forms of immunotherapies might miss, the researchers report Oct. 14 in the journal Nature Immunology.
Geneticist Greco Receives a Major Government Research Award
Valentina Greco, PhD, Carolyn Walch Slayman Professor of Genetics, has been awarded the National Institutes of Health (NIH) Director’s Pioneer Award. The grant, $3.5 million over the next five years, is inspired by Greco’s pioneering research into skin stem cells, which has revealed in intricate detail the secrets to their daily and ever-changing lives.
Yale Launches Comprehensive DNA Sequencing Project, With Aim of Predicting, Preventing, and Treating Gene-related Diseases
Generations, a collaboration between Yale School of Medicine and Yale New Haven Health System, is one of the largest DNA sequencing projects of its kind in the United States.
Horwich Is Co-recipient of $3 Million Breakthrough Prize
Arthur L. Horwich, MD, Sterling Professor of Genetics and professor of pediatrics, and his colleague F. Ulrich Hartl, from the Max Planck Institute, will share a 2020 Breakthrough Prize. This prize was developed by Sergey Brin, Mark Zuckerberg, Jack Ma, and Yuri Milner, together with their families, to honor the most accomplished life scientists.