Simple Change to Microscope Opens Up a Complex Panorama of Cells
Yale researchers in the lab of Joerg Bewersdorf have developed a way to visualize extremely tiny structures by using standard light microscopy, a world previously only accessible by expensive and cumbersome electron microscopy.Source: YaleNews
Yale Researchers Take Stem Cells One Step Closer to Replacing Parathyroid Gland Function
Yale investigators have developed a multistep process that models the biological instructions to create parathyroid gland cells from pluripotent stem cells, a significant milestone along the path toward helping people who lack the hormones released by parathyroid glands.
Position Openings in the Zhang lab
The Zhang lab at the Department of Cell Biology, Yale University, uses single-molecule approaches, especially high-resolution optical tweezers, to study folding dynamics of proteins involved in fundamental biological processes and human diseases. The lab is now seeking graduate students and postdocs for research in the following three areas: • Regulated SNARE folding and assembly. • Membrane protein folding, stability, and protein-membrane interactions. • Instrumental development. Prior research experience in single-molecule biophysics is not required. However, postdoc candidates should have strong quantitative skills and solid training in biophysics, molecular biology, or physics. If you are interested in these positions, please contact Dr. Yongli Zhang at firstname.lastname@example.org.
Scientists find many gene 'drivers' of cancer, but warn: Don't ignore 'passengers'
A massive analysis of the entire genomes of 2,658 people with 38 different types of cancer has identified mutations in 179 genes and gene regulators as “drivers” — variations in DNA sequences that lead to the development of cancer.
Colón-Ramos named McConnell Duberg Associate Professor
Daniel A. Colón-Ramos, PhD, recently appointed as Dorys McConnell Duberg Associate Professor of Neuroscience and Cell Biology, focuses his research on how synapses are formed and maintained to control behavior and store memories. Colón-Ramos’ discoveries have altered long-held views on the process and may offer important clues in the fight against disease.
Study Explores Role of Metabolism in Immune Cell Behavior
What makes healthy cells change and become dysfunctional to the point of causing disease? In addition to a disruption in genes that regulate cells, there is another factor in cell misbehavior that involves metabolism, say Yale researchers.
Protein-slaying Drugs Could Be the Next Blockbuster Therapies
A drug strategy called targeted protein degradation; and pursued by Craig Crews, PhD, Lewis B. Cullman Professor of Molecular, Cellular, and Developmental Biology, and professor of chemistry; capitalizes on the cell’s natural system for clearing unwanted or damaged proteins, and is in line to be used in promising clinical trials.Source: Nature
Of Worms and a Special Love of Home
Daniel Colón-Ramos works with the roundworm C. elegans as a means of advancing knowledge of the fundamental building blocks of the nervous system, saying that mastering the basics is essential to answering the bigger questions. He also has dedicated himself to improving opportunities for people in his native Puerto Rico.Source: Medicine@Yale
Ponce receives Paul Nelson Award from Council of Chairs of Training Councils
Allison Ponce, PhD, Associate Professor of Psychiatry, has received the Paul Nelson Award from the Council of Chairs of Training Councils (CCTC). CCTC is comprised of the presidents and chairs of the education and training associations in health service psychology with the mission of enhancing collaboration in psychology education.
Scientists find clues to mystery of Williams Syndrome’s peculiar symptoms
Patients with Williams Syndrome often are extremely social and possess a remarkable affinity and talent for music. They also experience life-threatening cardiovascular problems and developmental disabilities. The mystery is what happens during development to cause such peculiar symptoms.