Rogue Antibodies Wreak Havoc in Severe COVID-19 Cases
These autoantibodies target and react with a person’s tissues or organs similar to ones that cause autoimmune diseases such as lupus or rheumatoid arthritis. In COVID-19 cases they can attack healthy tissue in brain, blood vessels, platelets, liver, and the gastrointestinal tract, researchers report.Source: YaleNews
Yale Study Finds Elevated Suicide Risk for Older Adults Diagnosed With Dementia
Adults over age 65 who have been diagnosed with Alzheimer’s disease or other dementia are more than twice as likely to die from suicide compared to older adults who do not suffer from dementia, according to a new study led by Timothy Schmutte, PsyD, Assistant Professor of Psychiatry
WHRY Funds Studies on Heart Disease, Insomnia, and Pain
Women’s Health Research at Yale today announced funding for three new studies investigating a method for improving the diagnosis of heart disease in women, a therapy for clinically significant sleep disruption common in Black women, and the influence of biological sex on the underlying brain patterns that link pain and opioid use.
Yale Researchers Size up the Mental Health Toll of the Pandemic
While researchers have known about the mental health costs of chronic stress, they say this situation is unique because during the pandemic people have also lost many of the social connections and outlets needed to help manage their stress loads.Source: YaleNews
Yale, VA Researchers Investigate Eating Disorders in Iraq and Afghanistan War-Era Veterans
Researchers at Yale School of Medicine and the VA Connecticut Healthcare System, in a pair of complementary studies, investigated eating disorders in Iraq and Afghanistan war-era veterans, a group thought to be at high risk for the disorders.
Research Begun by WHRY Continues to Show Possible Pathway to Derail Dementia
Research is revealing the mechanisms that underlie the role of estradiol in memory so that next generation treatments for Alzheimer's disease and other dementias can specifically target these mechanisms and avoid the potential for negative side effects of systemic estrogen therapy.
Grilo Guest Co-Editor of Special Issue of Clinical Therapeutics
Carlos Grilo, PhD, Professor of Psychiatry and of Psychology and Director of the Yale Program for Obesity Weight and Eating Research, served as guest co-editor on the January 2021 special issue of Clinical Therapeutics, centered on the topic of eating disorders.
Genetic Analysis of Symptoms Yields New Insights Into PTSD
Attempts to identify the genetic causes of neuropsychiatric diseases such as post-traumatic stress disorder (PTSD) through large-scale genome-wide analyses have yielded thousands of potential links. The challenge is further complicated by the wide range of symptoms exhibited by those who have PTSD. For instance, does extreme arousal, anger, or irritation experienced by some have the same genetic basis as the tendency to re-experience traumatic events, another symptom of the disorder? A new study led by researchers at Yale and the University of California-San Diego (UCSD) provides answers to some of these questions and uncovers intriguing genetic similarities between PTSD and other mental health disorders such as anxiety, bipolar disorder, and schizophrenia.Source: Yale News
Scientists Unravel Mystery of Sex Disparities in COVID-19 Outcomes
"Age and sex are where immunological changes intersect,” says Akiko Iwasaki, PhD. Over the past year, Iwasaki and her colleagues from around the globe have compiled a rich literature of research that reveals in detail these and other factors that make the virus more lethal for men.Source: YaleNews
Understanding Immune System Blunders in Response to the Coronavirus
Genetics, gender, and even botched timing on the part of the immune response all appear important in the development of COVID-19. Akiko Iwasaki, PhD, is leading research to help us better predict who is likely to sail through a bout with COVID-19 and who may need targeted lifesaving care.
WHRY Funds Study on How CBD Affects the Brain
Women’s Health Research at Yale announced funding to investigate how the presumably non-intoxicating cannabis ingredient cannabidiol (CBD) affects the brain, and if it affects women and men differently. CBD use is growing in popularity exponentially, yet the safety and effectiveness of this non-regulated category of products are unknown.
Treatment with Genetically Altered Viruses Targets and Destroys Ovarian Cancer in Mice
Researchers have successfully eliminated chemotherapy-resistant ovarian cancer cells in mice using a single injection of two viruses genetically combined and altered to be safe, leading to long-term survival and demonstrating a potential breakthrough treatment for women.
WHRY Funds Study on Psychological Resilience in COVID-19 Health Care Providers
Women’s Health Research at Yale announced funding for a new collaborative study with researchers at Mt. Sinai Medical Hospital in New York on the personal and professional stressors and coping strategies of frontline health care providers confronting the COVID-19 pandemic