Yale Study: Ketamine Disinhibits Dendrites and Enhances Calcium Signals in Prefrontal Dendritic Spines
In a study published in Nature Communications, Alex Kwan, PhD, Associate Professor of Psychiatry, and his research team found that within an hour after a mouse received ketamine, there is a substantial increase in the amount of calcium that goes into the dendritic spines for neurons in the prefrontal cortex.
Yale Review: How Brain Alterations Contribute to Suicidal Thoughts and Behaviors
How brain alterations contribute to suicidal thoughts and behaviors is the subject of a new published review of brain scanning studies by Yale and international researchers. Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience, and Professor of Psychiatry, in the Child Study Center and of Radiology and Biomedical Imaging at Yale, is the paper's lead and corresponding author.
Lin, Chang Place 5th in International Natural Language Processing Competition
Eric Lin, MD, a fourth-year resident in the Yale Department of Psychiatry, and David Chang, a student in Yale's Computation Biology & Bioinformatics program, placed fifth in the National NLP Clinical Challenges (n2c2) Clinical Semantic Textual Similarity (STS) Task.
Yale Researchers Measure Ketamine's Effects on a Glutamate Receptor
Sophie Holmes, PhD, Associate Research Scientist in Psychiatry, and Irina Esterlis, PhD, Associate Professor of Psychiatry, are the first and senior authors, respectively, of a study published in Journal of Cerebral Blood Flow & Metabolism that measured the effects of the anesthetic ketamine on a glutamate receptor.
Yale Science Building Opens, Signaling New Era for Science Hill
The building has been hailed as the boldest development yet in Yale’s ambitious effort to further scientific research addressing some of the world’s most pressing problems. “In 100 years, when people look back to this moment, they will see that this was when we put a stake in the ground for our aspirations in research and education,” President Salovey said.
Study Suggests Role for Targeting Psychological Variables in the Treatment of Opioid Use Disorder and Chronic Pain
There is a paucity of evidence-based treatments for co-occurring opioid use disorder and chronic pain. These inter-related chronic medical conditions have been central to the unfolding of the opioid crisis. A new study by researchers at Yale, Johns Hopkins, University of Bridgeport, and Western Connecticut State University published in the Journal of Clinical Psychology suggests that psychological variables are important treatment targets for co-occurring opioid use disorder and chronic pain.
Yale Cancer Center Researchers Show Adding Radiation After Immunotherapy Improves Survival Time for Patients with Advanced Lung Cancer
The results of a phase II clinical trial by Yale Cancer Center (YCC) researchers show adding high-dose radiation after immunotherapy stops working increases survival time for patients with metastatic non-small-cell lung cancer (NSCLC).
Yale Radiology and Psychiatry Researchers Join with Penn Medicine to Create a New Center to Study Opioid Use Disorders
Opioid use disorder has reached epidemic levels in the United States. Over the last two decades, opioid-related overdose deaths increased by more than 50 percent, with nearly 50,000 in 2018, according to the Centers for Disease Control and Prevention. Researchers from Yale School of Medicine (YSM) and Penn Medicine, which comprises the Perelman School of Medicine at the University of Pennsylvania, have created a new center that focuses on neuroimaging to improve our understanding of opioid use disorders and find new treatments.
Yale Launches Comprehensive DNA Sequencing Project, With Aim of Predicting, Preventing, and Treating Gene-related Diseases
Generations, a collaboration between Yale School of Medicine and Yale New Haven Health System, is one of the largest DNA sequencing projects of its kind in the United States.