Grilo Guest Co-Editor of Special Issue of Clinical Therapeutics
Carlos Grilo, PhD, Professor of Psychiatry and of Psychology and Director of the Yale Program for Obesity Weight and Eating Research, served as guest co-editor on the January 2021 special issue of Clinical Therapeutics, centered on the topic of eating disorders.
Genetic Analysis of Symptoms Yields New Insights Into PTSD
Attempts to identify the genetic causes of neuropsychiatric diseases such as post-traumatic stress disorder (PTSD) through large-scale genome-wide analyses have yielded thousands of potential links. The challenge is further complicated by the wide range of symptoms exhibited by those who have PTSD. For instance, does extreme arousal, anger, or irritation experienced by some have the same genetic basis as the tendency to re-experience traumatic events, another symptom of the disorder? A new study led by researchers at Yale and the University of California-San Diego (UCSD) provides answers to some of these questions and uncovers intriguing genetic similarities between PTSD and other mental health disorders such as anxiety, bipolar disorder, and schizophrenia.Source: Yale News
Scientists Unravel Mystery of Sex Disparities in COVID-19 Outcomes
"Age and sex are where immunological changes intersect,” says Akiko Iwasaki, PhD. Over the past year, Iwasaki and her colleagues from around the globe have compiled a rich literature of research that reveals in detail these and other factors that make the virus more lethal for men.Source: YaleNews
Understanding Immune System Blunders in Response to the Coronavirus
Genetics, gender, and even botched timing on the part of the immune response all appear important in the development of COVID-19. Akiko Iwasaki, PhD, is leading research to help us better predict who is likely to sail through a bout with COVID-19 and who may need targeted lifesaving care.
WHRY Funds Study on How CBD Affects the Brain
Women’s Health Research at Yale announced funding to investigate how the presumably non-intoxicating cannabis ingredient cannabidiol (CBD) affects the brain, and if it affects women and men differently. CBD use is growing in popularity exponentially, yet the safety and effectiveness of this non-regulated category of products are unknown.
Treatment with Genetically Altered Viruses Targets and Destroys Ovarian Cancer in Mice
Researchers have successfully eliminated chemotherapy-resistant ovarian cancer cells in mice using a single injection of two viruses genetically combined and altered to be safe, leading to long-term survival and demonstrating a potential breakthrough treatment for women.
WHRY Funds Study on Psychological Resilience in COVID-19 Health Care Providers
Women’s Health Research at Yale announced funding for a new collaborative study with researchers at Mt. Sinai Medical Hospital in New York on the personal and professional stressors and coping strategies of frontline health care providers confronting the COVID-19 pandemic
WHRY Launches Studies on Endometrial Cancer, Addiction to Opioids, and Stroke
While continuing to focus on the impacts of COVID-19, the center has enlarged its research portfolio to include new projects on the prevention of endometrial cancer in a growing cohort of women at high risk, non-opioid pain management following a cesarean section for women with opioid use disorder who are in recovery, and sex differences in stroke.
Ivezaj: Language Matters: Patients’ Preferred Terms for Discussing Obesity and Disordered Eating with Health Care Providers After Bariatric Surgery
Many weight‐related and loss‐of‐control eating terms are viewed as undesirable. Health care providers should begin with neutrally rated terms and ask patients about their language preferences when speaking with individuals before/after bariatric surgery to improve patient‐centered care and reduce perceived weight bias.Source: Obesity: A Research Journal
Yale Researchers Take Stem Cells One Step Closer to Replacing Parathyroid Gland Function
Yale investigators have developed a multistep process that models the biological instructions to create parathyroid gland cells from pluripotent stem cells, a significant milestone along the path toward helping people who lack the hormones released by parathyroid glands.
New Study by Yale Psychiatry Researchers Identifies How to Better Screen for Perpetrators of Intimate Partner Violence
Despite increasing implementation of health care-based screening for intimate partner violence (IPV) victimization, there is little focus and evidence-base to inform practice and policy for IPV perpetration. Yet patients and health care providers tend to agree on many elements of how to effectively screen for IPV perpetration, a new study by Yale Psychiatry researchers concludes.
Yale Researchers Find Where Stress Lives
Yale researchers have found a neural home of the feeling of stress people experience, an insight that may help people deal with the debilitating sense of fear and anxiety that stress can evoke, Yale researchers report May 27 in the journal Nature Communications.