SLEEP-SMART Intervention Shows Promising Results for Women Suffering from Sleeping Problems, Depression, and Anxiety
Preliminary data indicate SLEEP-SMART can improve sleep patterns, show associated reductions in symptoms of depression and anxiety, and improve the functioning of brain circuits important in emotional and cognitive health.
Research Begun by WHRY Continues to Show Possible Pathway to Derail Dementia
Research is revealing the mechanisms that underlie the role of estradiol in memory so that next generation treatments for Alzheimer's disease and other dementias can specifically target these mechanisms and avoid the potential for negative side effects of systemic estrogen therapy.
Alzheimer's Disease Research Center will hold a research day on Feb. 12
The Alzheimer's Disease Research Center will be hosting a Research Day, which will include a series of lectures on current research studies on Alzheimer's Disease. The following Investigators will be presenting: Christopher van Dyck, MD; Jason Cai, PhD; Amy Arnsten, PhD; Morgan Levine, PhD; Nenad Sestan, MD,PhD; In Hyun Park, PhD; and Flora Vaccarino, MD.
How do we lose memory? A STEP at a time, researchers say
In mice, rats, monkeys, and people, aging can take its toll on cognitive function. A new study by researchers at Yale and Université de Montréal reveal there is a common denominator to the decline in all of these species — an increase in the level of the molecule striatal-enriched phosphatase, or STEP.
Research in the news: Hyperactive neurons may be culprit in Alzheimer’s
A long-term reduction in neuronal activity reduces amyloid plaques associated with Alzheimer’s disease, Yale University researchers have found. The study, using mouse models of Alzheimer’s, found the opposite is also true — triggering an increase in neuronal activity spurs creation of plaques and toxic amyloid beta peptides believed to trigger the disease.
Immune cells are an ally, not enemy, in battle against Alzheimer’s
In Alzheimer’s disease (AD), β-amyloid plaques are tightly enveloped by microglia but the significance of this phenomenon is unknown. Here the authors used confocal and in vivo two-photon imaging in AD mouse models and revealed that microglia constitute a physical barrier that prevents the formation of neurotoxic hotspots of protofibrillar β-amyloid and shields adjacent neurons and synapses from the toxic effect of amyloid plaques
Alzheimer’s missing link found: Is a promising target for new drugs
Yale School of Medicine researchers have discovered a protein that is the missing link in the complicated chain of events that lead to Alzheimer’s disease, they report in the Sept. 4 issue of the journal Neuron. Researchers also found that blocking the protein with an existing drug can restore memory in mice with brain damage that mimics the disease.
Improving emergency care for older adults
In the United States, adults aged 50 and older make more than 40 million trips to emergency departments (EDs) each year. And that number is expected to grow, Ula Hwang, MD, MPH, professor of emergency medicine at Yale School of Medicine discusses importance of making geriatric emergency care a priority.Source: YaleNews
Hwang among team of GEAR Network researchers focused on improving emergency care for people living with dementia
Ula Hwang, MD co-authors a new collection of research papers that set out priority areas to better provide emergency care for people living with dementia in the United States. Four papers and an accompanying editorial were published today in the Journal of the American Medical Directors Association. The GEAR Network is focused on areas of research that need to be undertaken to provide the best care for people living with dementia when they arrive at the emergency department.