Yale study finds ‘hyperhotspots’ that could predict skin cancer risk
New research by Yale Cancer Center scientists reports the discovery of “hyperhotspots” in the human genome, locations that are up to 170-times more sensitive to ultraviolet radiation (UV) from sunlight compared to the genome average.
HEALTH NOTES: Black and Hispanic Cancer Patients Are Underrepresented in Clinical Trials
A new study has shown that clinical trials for new cancer medications rarely analyze data on safety and effectiveness by race and that black and Hispanic patients are consistently underrepresented among participants.
Mutation Mystery: A Clinician Seeks Answers to Improve Skin Cancer Treatment for Women
Dr. Christine Ko has launched a study to see if a mutated gene can serve as a biological marker to predict the growth rate and recurrence of squamous cell carcinoma, a type of tumor of the thin outer layer of skin that affects about 700,000 Americans each year.
Women’s Health Research at Yale to Fund Four New Studies
With seed money through this year’s Pilot Project Program – including the second-ever Naratil Pioneer Award recipient for research on the verge of a significant breakthrough – the researchers aim to answer questions vital to improving women’s health.
The Scary Causes Behind the Rise in Skin-Cancer Rates
Because I spent the first 18 years of my life in south Florida, I learned early that people either love the sunshine or are, like me, shade-seeking vampires. My mother was in the first group—a member of the baby-oil-and-reflector club—until she was diagnosed with malignant melanoma, the most aggressive form of skin cancer, at age 23 (she found a second melanoma in 2000; both were removed with surgery).Source: Allure Magazine
Woman's Colleague Spots Mark on Her Arm That Led to Cancer Diagnosis
A rise in melanoma cases in recent years has led the American Cancer Society to estimate that approximately 97,610 new cases will be diagnosed in 2023, resulting in 7,990 deaths. Although the average age to receive a diagnosis is 65, melanoma can occur at any age and is prevalent in young females. Fortunately, there are ways to reduce the risk of melanoma or to catch it early. Dr. Jonathan Leventhal, the director of the Onco-Dermatology Program at Smilow Cancer Hospital and Yale Cancer Center said that UV exposure is the primary risk of skin cancer, so the importance of sun safety shouldn't be underestimated. "UV exposure is the greatest environmental risk factor, so prevention includes avoiding UV damage to the skin," Leventhal told Newsweek. "Avoid tanning beds, protect skin outdoors by seeking shade, wear protective clothing, hat, and sunglasses, apply broad-spectrum sunscreen SPF 30 or above, and reapply frequently.Source: Newsweek
Simon Roy, MD Awarded Grant for Diversifying Acral Melanoma Research
Yale Dermatology Clinical Instructor and Postdoctoral Fellow Simon Roy, MD has received a $50,000 Dermatology Fellowship Award from the Melanoma Research Alliance. This competitive grant boosts Dr. Roy's efforts to conduct research into acral melanoma - a rare and understudied melanoma subtype - among a diverse patient population.
Yale dermatologist warns of sun dangers
Yale Associate Professor of Dermatology Kathleen Suozzi, MD stresses the importance of protecting skin from the sun's harmful rays to prevent melanoma and offers tips on how to identify potentially dangerous changes in the skin's appearance.Source: WTNH News8
Yale Cancer Center Warns About Melanoma Risks as Summer Heats Up
The hot weather may be bringing more people outside this week, but it may come at a cost. The next time you go to the beach consider your skin. "Every sunburn is dangerous," said Dr. Kathleen Suozzi, dermatologic surgeon at Yale Cancer Center.Source: News12 Connecticut
Psoriasis on the Knees and Elbows: What It Looks Like, How to Treat It
She’s been mortified by these flares since childhood. “As a kid, I’d go to day camp wearing jeans and long-sleeved shirts — and I never, ever wore a bathing suit,” she recalls. The knees and elbows are the most common location for psoriasis flare-ups. “Those are the textbook cases,” says Elisabeth Richard, MD, an assistant professor of dermatology at the Johns Hopkins University School of Medicine in Baltimore. Psoriasis on these body parts tends to have a distinctive appearance: “You’ll usually see a well-circumscribed plaque, bigger than a centimeter, with thickened skin and overlying white scales,” Dr. Richard explains. Plaques may appear red or salmon pink on white skin and purple or brown on Black or brown skin. Psoriasis most often appears on the front of the knees and the elbows, known as extensor surfaces, says Jeffrey Cohen, MD, an assistant professor of dermatology and director of the psoriasis treatment program at Yale Medical School in New Haven, Connecticut.Source: Everyday Health
Chemical Hair Straighteners and Cancer: What You Need to Know
If you are a woman who has used chemical hair straightening products, a new report issued by the National Institutes of Health may have caused you concern. The NIH released findings that link chemical hair straightening products to uterine cancer. These results might cause you to question your own use of hair care products and wonder what you should do next. For now, experts suggest that there is no need to panic. More research is needed before we know for sure which ingredients may be problematic. But still, women of color and others who use these products are (reasonably) worried. We talked to both medical and hair care experts to get some answers to ease your mind.Source: Health & Wellness
Microneedling Can Help Surgical Scars Fade, Especially If Done Early
A technique called microneedling may help surgical scars heal more attractively — especially if it's done within a couple of months of surgery, a small study suggests. Researchers found that for 25 patients, microneedling improved the long-term appearance of scars after various types of surgery — based on both patient and doctor ratings. But the sooner it was done, the better. Patients who underwent their first microneedling session within six or seven weeks of surgery had the best results. That, the researchers said, goes against the "conventional wisdom," which holds that microneedling should be delayed until scars are about a year old.Source: U.S. News
Yale dermatologist seeing skin cancer in younger people
Skin cancer is the most common form of cancer and it is completely preventable. With the Memorial Day weekend almost here and a nice forecast ahead, Yale Medicine Dermatologist Kathleen Suozzi warns people to protect their skin. She does not like a trend she is now treating. “I have patients, I’m seeing patients in their twenties, in their thirties developing skin cancer and this is alarming because we know that once you develop a skin cancer you’re at increased risk for all additional skin cancers,” Suozzi said. Suozzi said to pay attention to what the UV index is if you plan to spend time outdoors. It is the strength of the sunburn-producing ultraviolet radiation. Numbers 8 through 10 mean it is high. She said mid-summer is not the only time when sun danger is high. “In general, the UV indexes we will see around this area will peak around mid-summer, so late July, early August but certainly on spring days we can see higher UV indexes that are looking more like our summer levels.”Source: News 8