Study Identifies Neuronal Basis of Impaired Consciousness in Absence Epilepsy
Using a genetic model known as Genetic Absence Epilepsy Rats of Strasbourg (GAERS), Yale researchers have identified the neuronal basis for absence epilepsy. Their findings were published Jan. 10 in Nature Communications. During absence epilepsy episodes, children experience brief staring spells, during which they temporarily lose consciousness. Absence seizures can be captured by abnormal rhythms on EEG recordings, but their neuronal cause has never before been identified.
Research Applies Machine Learning/AI to Predict Consciousness for Driving in People with Epilepsy
A new study published in September 2022 in Annals of Clinical and Translational Neurology may guide doctors in how to proceed when they observe SWDs on EEG, but are unclear of the patient’s neurological capacity for driving. Led by Principal Investigator Hal Blumenfeld, MD, PhD, researchers have harnessed the power of machine learning/artificial intelligence (AI) to address the shortcomings of traditional testing.
Less Wattage, More Brain Power
Dennis Spencer, MD, the Harvey and Kate Cushing Professor Emeritus of Neurosurgery, and Hitten Zaveri, PhD, assistant professor of neurology are collaborating with researchers at the Yale School of Engineering and Applied Science to expand the treatment capabilities of Brain-Computer Interfaces for patients who suffer from conditions like epilepsy and paralysis.Source: Yale News/Yale Engineering Magazine)
Improving treatment for psychogenic seizures: “This is a group of patients that we are taking less seriously”
Tolchin designed a study - and is currently developing an app - using motivational interviewing (MI) as an intervention to improve treatment adherence in people with psychogenic non-epileptic seizures (PNES).Source: newswise
Newly Discovered Seizure Disorder Mimics Epilepsy
Recent research suggests that about 10 percent of patients previously diagnosed with epilepsy don’t have epilepsy at all. These patients are actually having a different kind of seizure known as a “psychogenic non-epileptic seizure” or PNES.Source: Yale Medicine
A new hope for surgical epilepsy patients: a new technique increases the chance of complete seizure freedom and may spare the patients, risks and invasive procedures
Recording of seizures during routine MEG in some surgical candidates can help precisely identify affected areas of the brain and, in a few cases, even negate the need to conduct invasive intracranial EEG evaluations prior to surgery, the authors say. Lead author of the study published June 11 in the journal JAMA Neurology is Dr. Rafeed Alkawadri, Director of Yale Human Brain Mapping Program. Dr. Andreas Alexopoulos of the Cleveland Clinic is senior author of the paper.
Blumenfeld receives prestigious award that supports research into seizures
Yale School of Medicine professor Hal Blumenfeld has received a prestigious award from the National Institute of Neurological Disorders and Stroke, which will support his work for seven years as he investigates important properties of seizures.
Kavli Q&A: Hal Blumenfeld on what epilepsy is teaching us about consciousness
For centuries, the nature of consciousness has been a question for philosophers. That began to change in the late 20th century when scientists such as Francis Crick, the co-discoverer of DNA, argued that it is a tractable scientific problem. Yale’s Hal Blumenfeld is helping to prove Crick right by using the increasingly sophisticated tools of neuroscience to find the biological basis of consciousness.
Yadav Receives American Epilepsy Society Postdoctoral Research Fellowship
The American Epilepsy Society (AES) has awarded Postdoctoral Associate Taruna Yadav, PhD with a $50,000 Postdoctoral Research Fellowship. This competitive fellowship supports Dr. Yadav’s research into using a wearable technology - the ARTiE Watch - to quantify impaired consciousness in epilepsy.
A Staring Spell
Hal Blumenfeld, MD, PhD, Yale School of Medicine professor of neurology and director of the Yale Clinical Neuroscience Imaging Center, describes the journey of validating an animal for measuring behavioral response during absence epilepsy, understanding the neuronal basis for the condition, and the path toward identifying targeted therapies.Source: Yale Scientific
Yale School of Medicine starting trials on new epilepsy treatment that uses smart technology
About one-third of people diagnosed with epilepsy are not able to get relief from treatments currently available. Now, researchers at Yale University School of Medicine and two other locations are beginning trials on a new and innovative treatment that uses smart technology.Source: WTNH News 8