2021
Accounting for quality improvement during the conduct of embedded pragmatic clinical trials within healthcare systems: NIH Collaboratory case studies
Tuzzio L, Meyers CM, Dember LM, Grudzen CR, Melnick ER, Staman KL, Huang SS, Richards J, DeBar L, Vazquez MA, Green BB, Coronado GD, Jarvik JG, Braciszewski J, Ho PM, Wells BL, James K, Toto R, D’Onofrio G, Volandes A, Kuklinski MR, Catalano RF, Sterling SA, Morse EF, Curtis L, Larson EB. Accounting for quality improvement during the conduct of embedded pragmatic clinical trials within healthcare systems: NIH Collaboratory case studies. Healthcare 2021, 8: 100432. PMID: 34175091, PMCID: PMC8900087, DOI: 10.1016/j.hjdsi.2020.100432.Peer-Reviewed Original ResearchConceptsPragmatic clinical trialsQI initiativesHealthcare systemClinical trialsHigh-quality patient-centered careClinical practice guidelinesHigh-quality evidencePatient-centered careQuality of careQuality improvement activitiesPractice guidelinesRoutine collaborationHealth questionsHealth systemTrialsHealth system operationsConduct phaseCareStudy teamPublic healthInterventionImprovement activitiesEPCTs
2017
Multiple Fentanyl Overdoses — New Haven, Connecticut, June 23, 2016
Tomassoni AJ, Hawk KF, Jubanyik K, Nogee DP, Durant T, Lynch KL, Patel R, Dinh D, Ulrich A, D’Onofrio G. Multiple Fentanyl Overdoses — New Haven, Connecticut, June 23, 2016. MMWR Morbidity And Mortality Weekly Report 2017, 66: 107-111. PMID: 28151928, PMCID: PMC5657834, DOI: 10.15585/mm6604a4.Peer-Reviewed Case Reports and Technical NotesConceptsIntensive care unitEmergency departmentYale-New Haven HospitalEmergency medical services (EMS) crewsInterviews of patientsContinuous naloxone infusionNew Haven HospitalPublic health alertsRespiratory failureCare unitNaloxone infusionEndotracheal intubationOpioid overdoseNaloxone distributionPatientsRoute of intoxicationSubsequent episodesHealth alertsOpioid antidoteFentanylHospitalPublic healthFamily membersCocaineRapid notification
2009
Emergency Medicine Public Health Research Funded by Federal Agencies: Progress and Priorities
D’Onofrio G, Goldstein AB, Denisco RA, Hingson R, Heffelfinger JD, Post LA. Emergency Medicine Public Health Research Funded by Federal Agencies: Progress and Priorities. Academic Emergency Medicine 2009, 16: 1065-1071. PMID: 20053224, DOI: 10.1111/j.1553-2712.2009.00555.x.Peer-Reviewed Original ResearchConceptsEmergency medicineEmergency department visitsNational InstituteAcademic Emergency Medicine consensus conferenceDepartment of HealthDepartment visitsPublic health researchAlcohol abuseConsensus conferenceDisease controlDrug abuseMental healthHealth researchPublic healthMedical disciplinesHealthPreventionStudy Designs and Evaluation Models for Emergency Department Public Health Research
Broderick KB, Ranney ML, Vaca FE, D’Onofrio G, Rothman RE, Rhodes KV, Becker B, Haukoos JS. Study Designs and Evaluation Models for Emergency Department Public Health Research. Academic Emergency Medicine 2009, 16: 1124-1131. PMID: 20053232, PMCID: PMC3082772, DOI: 10.1111/j.1553-2712.2009.00557.x.Peer-Reviewed Original ResearchConceptsPublic health researchHealth researchStudy designActual clinical practiceAcademic Emergency Medicine consensus conferencePublic health investigatorsEmergency departmentPublic health workConsensus conferenceMethodologic featuresClinical practiceHealth investigatorsHealth workPublic healthRigorous program evaluationProgram evaluationEDFuture investigationsParticipant selectionBreakout sessionsThoughtful consideration