COCAINE SELF-ADMINISTRATION BEHAVIOR IS ASSOCIATED WITH SUBCORTICAL AND CORTICAL GRAY MATTER IN INDIVIDUALS WITH COCAINE USE DISORDER
Kohler R, Zhornitsky S, Potenza M, Yip S, Worhunsky P, Angarita G. COCAINE SELF-ADMINISTRATION BEHAVIOR IS ASSOCIATED WITH SUBCORTICAL AND CORTICAL GRAY MATTER IN INDIVIDUALS WITH COCAINE USE DISORDER. Drug And Alcohol Dependence 2024, 260: 110081. DOI: 10.1016/j.drugalcdep.2023.110081.Peer-Reviewed Original ResearchStructural brain changes associated with cocaine use and digital cognitive behavioral therapy in cocaine use disorder treatment
McCurdy L, DeVito E, Loya J, Nich C, Zhai Z, Kiluk B, Potenza M. Structural brain changes associated with cocaine use and digital cognitive behavioral therapy in cocaine use disorder treatment. Drug And Alcohol Dependence Reports 2024, 11: 100246. PMID: 38966567, PMCID: PMC11222934, DOI: 10.1016/j.dadr.2024.100246.Peer-Reviewed Original ResearchCocaine use disorderCognitive behavioral therapyCocaine useBehavioral therapyBrain changesBrain structuresWhole-brain voxel-based morphometry analysisCocaine use disorder treatmentLevel of cocaine useWeeks of outpatient treatmentVoxel-based morphometry analysisDigital cognitive behavioral therapyT1-weighted magnetic resonance imaging scansRight caudate bodyAssociated with cocaine useMethadone-maintained individualsGray matter volumeStructural brain changesFunction of engagementCaudate bodyRight caudateCUD treatmentMatter volumeUse disorderBilateral cerebellumWanting-liking dissociation and altered dopaminergic functioning: Similarities between internet gaming disorder and tobacco use disorder
Ma X, Wang M, Zhou W, Zhang Z, Ni H, Jiang A, Zheng Y, Du X, Potenza M, Dong G. Wanting-liking dissociation and altered dopaminergic functioning: Similarities between internet gaming disorder and tobacco use disorder. Journal Of Behavioral Addictions 2024, 13: 596-609. PMID: 38635338, PMCID: PMC11220823, DOI: 10.1556/2006.2024.00011.Peer-Reviewed Original ResearchInternet gaming disorderTobacco use disorderIGD participantsGaming disorderCue-craving taskImplicit Association TestBrain-behavior mechanismsHealthy control participantsImplicit association test resultsFunctional MRI dataNeuromelanin-sensitive MRIIncentive sensitizationAddiction severityDopaminergic involvementDSM-5Dopaminergic functionDopaminergic systemPotential dissociationUse disorderControl participantsBrain featuresHedonic responsesAssociation TestGaming motivesNeural featuresSex, Adverse Childhood Experiences, and Substance Use Disorders in US Military Veterans: Results From the National Health and Resilience in Veterans Study
Moore A, Stefanovics E, Jankovsky A, Potenza M, Pietrzak R. Sex, Adverse Childhood Experiences, and Substance Use Disorders in US Military Veterans: Results From the National Health and Resilience in Veterans Study. Journal Of Addiction Medicine 2024, 18: 432-436. PMID: 38598295, DOI: 10.1097/adm.0000000000001306.Peer-Reviewed Original ResearchCurrent alcohol use disorderAlcohol use disorderSubstance use disordersDrug use disordersAdverse childhood experiencesNational Health and ResilienceUse disorderVeterans StudyChildhood experiencesSexual abuseMentally ill family memberSex moderated associationsSelf-report measuresChildhood sexual abuseUS military veteransIncarcerated family memberChildhood traumaPhysical neglectIll family memberMilitary veteransFemale veteransMale veteransFamily membersTreatment effortsModerate associationIntrinsic connectivity demonstrates a shared role of the posterior cingulate for cue reactivity in both gambling and cocaine use disorders
Vaccaro A, Lacadie C, Potenza M. Intrinsic connectivity demonstrates a shared role of the posterior cingulate for cue reactivity in both gambling and cocaine use disorders. Addictive Behaviors 2024, 155: 108027. PMID: 38581751, PMCID: PMC11273263, DOI: 10.1016/j.addbeh.2024.108027.Peer-Reviewed Original ResearchConceptsCocaine use disorderPosterior cingulate cortexCue reactivityBehavioral addictionsUse disorderGambling disorderPosterior cingulatePosterior cingulate cortex connectivityHealthy comparison subjectsIntrinsic connectivity distributionIntervention developmentCocaine cuesFMRI taskAddictive disordersCingulate cortexComparison subjectsNeurobiological foundationsSad videosDecreased connectivityFunctional connectivityCocainePost hoc analysisAddictionRelevant to maintenanceGamblingCocaine self-administration behavior is associated with subcortical and cortical morphometry measures in individuals with cocaine use disorder
Kohler R, Zhornitsky S, Potenza M, Yip S, Worhunsky P, Angarita G. Cocaine self-administration behavior is associated with subcortical and cortical morphometry measures in individuals with cocaine use disorder. The American Journal Of Drug And Alcohol Abuse 2024, 50: 345-356. PMID: 38551365, PMCID: PMC11305926, DOI: 10.1080/00952990.2024.2318585.Peer-Reviewed Original ResearchGray-matter volumeSelf-administer cocaineSelf-administration behaviorCocaine use disorderSelf-administrationGray-matterFrontal cortexUse disorderCocaine self-administration behaviorSelf-administered cocaine infusionsCocaine self-administrationSelf-administration paradigmInfusions self-administeredSelf-report assessmentsCortical brain regionsStructural MRI dataFR1 scheduleInsular thicknessCocaine infusionsPredisposing vulnerabilitiesCocaine consumptionCocaine useBrain regionsBilateral regionsLimbic systemObesity in Latinx and White U.S. military veterans: Mental health, psychosocial burden, non-suicidal self-injury and suicidal behavior
Stefanovics E, Grilo C, Potenza M, Pietrzak R. Obesity in Latinx and White U.S. military veterans: Mental health, psychosocial burden, non-suicidal self-injury and suicidal behavior. Psychiatry Research 2024, 335: 115844. PMID: 38484606, DOI: 10.1016/j.psychres.2024.115844.Peer-Reviewed Original ResearchNon-suicidal self-injuryDrug use disordersU.S. military veteransMental health problemsMilitary veteransSelf-injuryUse disorderSymptoms of internalizing disordersLevels of childhood traumaNational Health and ResiliencePost-traumatic stress disorderIncreased risk of mental health problemsWhite veteransCoping self-efficacyRisk of mental health problemsLatinx ethnicityGeneralized anxietyStress disorderChildhood traumaHealth problemsSuicidal behaviorVeterans StudyCorrelates of obesityCulturally sensitive preventionNationally representative sample