1995
Mek MAPK/Erk kinase (vertebrates) (MAP kinase kinase, MAPKK)
Erikson R, Alessandrini A, Crews C. Mek MAPK/Erk kinase (vertebrates) (MAP kinase kinase, MAPKK). 1995, 275-277. DOI: 10.1016/b978-012324719-3/50085-6.Peer-Reviewed Original ResearchMAPK/ERK kinaseMAP kinaseERK kinaseReversible protein phosphorylationAmino acid sequenceRelated gene productsMEK1/MEK2Microtubule-associated proteinsOutside vertebratesPhosphorylation eventsERK2 geneProtein phosphorylationKinase domainRaf-1MEK kinaseGene productsAcid sequenceTyrosine residuesFusion proteinKinaseMouse tissuesExogenous substratesByr1MEKProtein
1992
The Primary Structure of MEK, a Protein Kinase that Phosphorylates the ERK Gene Product
Crews C, Alessandrini A, Erikson R. The Primary Structure of MEK, a Protein Kinase that Phosphorylates the ERK Gene Product. Science 1992, 258: 478-480. PMID: 1411546, DOI: 10.1126/science.1411546.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceCalcium-Calmodulin-Dependent Protein KinasesGene ExpressionMAP Kinase Kinase 1MiceMitogen-Activated Protein Kinase KinasesMolecular Sequence DataPhosphorylationProtein KinasesProtein Serine-Threonine KinasesProteinsProtein-Tyrosine KinasesRNA, MessengerSequence AlignmentConceptsExtracellular signal-regulated kinaseProtein kinaseMAP kinaseGene productsCritical protein kinaseSignal-regulated kinaseComplementary DNA sequenceMEK genesExtracellular signalsERK kinaseMultiple biochemical signalsDNA sequencesBiochemical signalsPrimary structureKinaseAmino acidsEnzymatic activityGenesMurine brainSequenceSchizosaccharomycesMEK1MEKThreonineProtein