Research Departments & Organizations
Psychiatry: Connecticut Mental Health Center | Neurocognition, Neurocomputation, and Neurogenetics, Division of | Psychosis Program at Yale | Specialized Treatment for Early Psychosis (STEP) Program
Dr. Srihari is seeking to determine how best to provide care to individuals who have recently experienced the onset of psychotic symptoms. He directs a research clinic that provides multi-disciplinary care to such individuals while also collecting outcomes to inform an assessment of the cost-effectiveness of such care. The overall goal is to articulate a model of care that can be implemented in community settings across the U.S. to promote the functional recovery of individuals with psychotic illnesses.
Extensive Research Description
The STEP program is engaged in a variety of research projects across the translational continuum with several allied laboratories. The subset of projects that Dr. Srihari is currently a funded Principal Investigator are:
1. NIH R01: Test of a population based strategy to reduce Duration of Untreated Psychosis (Srihari, 2013-)
2. DONAGHUE R3: Web-based tool/ dissemination of STEP model (Cahill&Srihari, 2015-):
3. NIH R01: Multi-model Assessment of Social Process Systems across Autism * Psychosis (McPartland/Srihari, 2015-)
4. NIH Supplement: Inflammatory biomarkers for treatment response and illness trajectories (Srihari, 2015-)
|Mental Health & Behavioral Research||A Four-week Clinical Trial Investigating Efficacy and Safety of Cannabidiol as a Treatment for Acutely Ill Schizophrenic Patients|
|Mental Health & Behavioral Research||STEP-ED: Reducing Duration of Untreated Psychosis and Its Impact in the U.S.|
Pathways and Delays to Care in Kingston, Jamaica Kingston, Jamaica (2018)
Study of early onset schizophrenia Kunming, China (2015)
DUP Reduction collaborative study Stavanger, Norway; Oslo, Norway; Boston, United States (2013 - 2019)
Early Intervention for Psychotic Disorders: Building Population Health Systems.
Srihari VH, Jani A, Gray M. Early Intervention for Psychotic Disorders: Building Population Health Systems. JAMA Psychiatry 2016, 73:101-2. 2016
Reducing the duration of untreated psychosis and its impact in the U.S.: the STEP-ED study.
Srihari VH, Tek C, Pollard J, Zimmet S, Keat J, Cahill JD, Kucukgoncu S, Walsh BC, Li F, Gueorguieva R, Levine N, Mesholam-Gately RI, Friedman-Yakoobian M, Seidman LJ, Keshavan MS, McGlashan TH, Woods SW. Reducing the duration of untreated psychosis and its impact in the U.S.: the STEP-ED study. BMC Psychiatry 2014, 14:335. 2014
First-Episode Services for Psychotic Disorders in the U.S. Public Sector: A Pragmatic Randomized Controlled Trial.
Srihari VH, Tek C, Kucukgoncu S, Phutane VH, Breitborde NJ, Pollard J, Ozkan B, Saksa J, Walsh BC, Woods SW. First-Episode Services for Psychotic Disorders in the U.S. Public Sector: A Pragmatic Randomized Controlled Trial. Psychiatric Services (Washington, D.C.) 2015, 66:705-12. 2015
Bringing neuroscience to teaching rounds: Refreshing our clinical pidgin.
Srihari VH. Bringing neuroscience to teaching rounds: Refreshing our clinical pidgin. Asian Journal Of Psychiatry 2015, 17:138-9. 2015
Evidence-based medicine in the education of psychiatrists.
Srihari V. Evidence-based medicine in the education of psychiatrists. Academic Psychiatry : The Journal Of The American Association Of Directors Of Psychiatric Residency Training And The Association For Academic Psychiatry 2008, 32:463-9. 2008
Cardiovascular mortality in schizophrenia: defining a critical period for prevention.
Srihari VH, Phutane VH, Ozkan B, Chwastiak L, Ratliff JC, Woods SW, Tek C. Cardiovascular mortality in schizophrenia: defining a critical period for prevention. Schizophrenia Research 2013, 146:64-8. 2013