Skip to Main Content

Program for the Promotion of Interdisciplinary Team Science (POINTS)

Call for Applications

Important Dates:

  • Letter of Intent Submission Deadline: Monday, 08/09/21
  • Full Application Deadline: Monday, 10/04/21
  • Project Start Date: Monday, 12/01/21

Award Amount: from $50,000 up to a maximum total award of $200,000 for a project period of one to two years.

Purpose: to provide seed money to teams of investigators within the Yale School of Medicine community to generate preliminary data and evidence of collaboration sufficient to obtain extramural funding, such as multi-investigator u01, u54, p01, or p30 grants.

Eligibility: teams of scientists led by a Yale School of Medicine faculty member may apply.

Requirements: pis and all project leaders must agree to abide by grant guidelines.

Review Criteria and Process: major review criteria for this award are scientific excellence and likelihood that the proposed program will result in

  1. The advancement of an interdisciplinary approach to address an important question in biomedical translational science and
  2. The submission of a multi-project grant application such as a u01, u54, p01, or p30.

Applications will undergo a two-step review process:

  1. Letters of intent will be solicited to confirm project alignment with points objectives.
  2. A limited number of proposals will be invited to submit a full application for review by a panel appointed by the dean of Yale School of Medicine. POINTS award applications do not need to be sent to the office of sponsored projects.

Phase 1: Letter of Intent

Letters of Intent Shall Contain the Following:

  1. Descriptive proposal title
  2. PI name and contact information
  3. Senior and/or key personnel names
  4. Statement addressing the overall objective of the project describing the potential to
    1. advance an interdisciplinary approach to address an important question in basic, clinical, and/or translational science and
    2. result in the submission of a multi-project grant application such as a U01, U54, P01, or P30
  5. Specific Aims
  6. List of collaborative publications and/or joint grants among POINTS team members (if applicable)

Phase 2: Full Application

Overall Section for multi-project applications

  1. Face page to include
    1. application title
    2. PI name, title, department, and contact information
    3. project titles
    4. project leader name(s), title(s), and department(s)
  2. Abstract (500-word maximum) of overall project
  3. Description (500-word maximum) of how the proposed program will facilitate
    1. an interdisciplinary approach to address an important question in basic, clinical, and/or translational science
    2. the submission of a multi-project grant application such as a U01, U54, P01, or P30
  4. Description (two pages) of overall aims, background, and significance.
  5. Consolidated budget incorporating all proposed projects, signed by PI’s business office (OSP approval not required).
  6. NIH biosketch for PI
  7. NIH other support for PI

For each Project and Core:

  1. Face page to include
    1. project title
    2. project leader name(s), department(s), and contact information
    3. project personnel name(s), department(s), and contact information
  2. Abstract (300-word maximum) for the project
  3. Specific Aims (three pages) for each project, including background and significance, preliminary data, and experimental design and methods
  4. Budget for each project signed by project leader’s business office
  5. NIH biosketches for project leader and all collaborating faculty
  6. NIH other support for project leader and all collaborating faculty
  7. Status of human subject protocols, including protocol number, approval date, approval period, and title
  8. Status of vertebrate animal protocols, including protocol number, approval date, approval period, and title
  9. Letters of collaboration

Expenditures Allowed:

  • no more than 25% effort each (salary and fringe) for any personnel working on this research project
  • personnel support for biostatistical analysis (no more than 25% effort)
  • laboratory supplies and expenses, including animal costs
  • user fees for core facilities
  • costs related to tissue collection and analysis
  • equipment costs (up to $2,500). Title to equipment shall be vested in the Institution.

Expenditures NOT Allowed:

  • faculty salary support (NOTE: faculty member’s department is responsible for salary/fringe associated with faculty effort)
  • secretarial/administrative personnel
  • office equipment and supplies; office and laboratory furniture
  • tuition
  • publication costs, including reprints
  • registration fees for scientific meetings
  • purchasing or binding of periodicals and books
  • dues and membership fees in scientific societies
  • travel expenses

Additional Information

Application Notes:
  • Actual awards may be less than the requested amount.
  • Protocols need not obtain IRB/ IACUC approval prior to submission, but funding may be contingent upon approval.
  • NIH format restrictions apply (Arial 11 font; margins one-half inch all around). Figures are included in the page limit; references are not included in the page limit.

Progress Reports:

  • All publications and/or grants resulting from this award must be promptly reported in progress reports or supplemental progress reports, if after completion of the above reporting cycle. If funding acknowledgement to another existing grant is present in the publication, please also note.
  • During the funding period, recipients will be asked to meet for a review of progress and to submit written progress reports. Grant recipients shall respond promptly to requests for information from the scientific leadership and administrative staff.
  • Expenditures: Funds shall be expended in full during the one- to two-year duration of the grant. Spending will be monitored, and unspent funds may be reclaimed if spending lags significantly.
  • Use of funds shall be restricted to those allowable expenses outlined above.

Review Criteria and Process:

Major review criteria for this award are scientific excellence and likelihood that the proposed program will result in:

  1. the advancement of an interdisciplinary approach to address an important question in biomedical translational science and
  2. the submission of a multi-project grant application such as a U01, U54, P01, or P30.

Proposals will be reviewed by a panel appointed by the Dean of Yale School of Medicine. POINTS award applications do not need to be sent to the Office of Sponsored Projects.

NOTE: Resubmissions will be allowed on a case-by-case basis. A new letter of intent is not needed, but a review studio will be required prior to resubmission.