Research Departments & Organizations
The overarching goal of the lab is to investigate molecular basis of diseases. We study signaling pathways in development and cell physiology, and strive to identify how the temporally and spatially inappropriate activity of these fundamental regulators can drive disease states. Current interests center on: (1) polarity signaling in neuronal development and regeneration, and aberrant polarity signaling in glioblastoma. (2) Neural and immune cell interaction in CNS development, regeneration and cancer. The goal of our studies is to unlock the potential for precision medicine by specifically targeting molecular pathways.
Specialized Terms: Neuronal polarity and axon specification in neurodevelopment and regeneration; immune cells and regeneration; astrocyte polarity signaling and glioblastoma; immune cells in glioblastoma;