Saral Mehra, MD, MBA, FACS

Assistant Professor of Surgery (Otolaryngology)

Research Departments & Organizations

Surgery: Otolaryngology Surgery: Head & Neck Cancer Surgery Program

HPV Working Group (Niccolai Lab)

Yale Cancer Center

Office of Cooperative Research

Research Interests

Head and Neck Neoplasms; Health Services Research; Microsurgery; Minimally Invasive Surgical Procedures; Reconstructive Surgical Procedures

Clinical Trials

Conditions Study Title
Other Skin A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate Pembrolizumab Versus Placebo as Adjuvant Therapy Following Surgery and Radiation in Participants With High-risk Locally Advanced Cutaneous Squamous Cell Carcinoma (LA cSCC) (KEYNOTE-630)
Esophagus, Larynx, Lip, Oral Cavity and Pharynx Randomized Phase II/III Trial of Radiotherapy With Concurrent MEDI4736 (Durvalumab) vs. Radiotherapy With Concurrent Cetuximab in Patients With Locoregionally Advanced Head and Neck Cancer With a Contraindication to Cisplatin
Larynx, Lip, Oral Cavity and Pharynx A Phase I Study of M6620 (VX-970) in Combination With Cisplatin and XRT in Patients With Locally Advanced HPV (-) Head and Neck Squamous Cell Carcinoma (HNSCC; SDC 10060121)
Lip, Oral Cavity and Pharynx Phase II Randomized Trial of Neo-Adjuvant Chemotherapy Followed by Surgery and Post-Operative Radiation Versus Surgery and Post-Operative Radiation for Organ Preservation of T3 and T4a Nasal and Paranasal Sinus Squamous Cell Carcinoma (NPNSCC)
Other Skin A Phase 2, Open-Label, Single Arm Study to Evaluate the Safety and Efficacy of Pembrolizumab in Participants With Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma (R/M cSCC)
Larynx, Lip, Oral Cavity and Pharynx Single-Arm Phase II Trial of Dual Inhibition of EGFR With Afatinib and Cetuximab With Correlative Studies in the Second-Line Treatment of Recurrent or Metastatic Squamous Cell Cancers of the Head and Neck
Larynx, Lip, Oral Cavity and Pharynx, Ill-Defined Sites A Phase II Study of Pembrolizumab for Patients With Head and Neck Squamous Cell Carcinoma With Residual Disease Following Definitive Chemoradiation
Lip, Oral Cavity and Pharynx Individualized Treatment in Treating Patients With Stage II-IVB Nasopharyngeal Cancer Based on EBV DNA


  • Striving for a New and Improved National Thyroid Cancer Database Toronto, ON, Canada (2013 - 2013)

  • Improving the Quality of Thyroid Cancer Care: How Does the Thyroid Cancer Care Collaborative Cross the Institute of Medicine‚Äôs Quality Chasm? Toronto, ON, Canada (2013 - 2013)

  • Facial Nerve Monitoring in Resection of Complex Vascular Malformations of the Head and Neck: Description and outcomes of a new methodology. San Diego, United States (2012 - 2012)

  • The role of otolaryngologists in anterior approaches to the cervical spine: a review of 193 consecutive cases. Miami, United States (2012 - 2012)

  • Case Series with Endoscopic Findings of a Novel Nasal Irrigation Protocol San Francisco, United States (2011 - 2011)

Selected Publications

See list of PubMed publications

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Contact Info

Saral Mehra, MD, MBA, FACS
Office Location
Yale OtolaryngologyCollege Place
37-55 College Street

New Haven, CT 06510
Mailing Address
Otolaryngology SurgeryP.O. Box 208041
New Haven, CT 06520

Curriculum Vitae