R Peter Manes, MD, FACS

Associate Professor of Surgery (Otolaryngology); Associate Residency Program Director, Yale Medicine; Director, Patient Safety and Quality, Division of Otolaryngology, Yale Medicine

Research Departments & Organizations

Surgery: Otolaryngology Surgery: Head & Neck Cancer Surgery Program

HHT Program

Office of Cooperative Research

Research Interests

Inflammation; Minimally Invasive Surgical Procedures; Nose Neoplasms; Otolaryngology; Otorhinolaryngologic Diseases; Paranasal Sinus Neoplasms; Sinusitis

Research Summary

My research interests parallel my clinical focus. Chronic sinusitis and intranasal inflammation are an interest. Furthermore, my research focuses on minimally invasive, endoscopic treatments of nasal and sinus tumors.

Specialized Terms: Nasal and Sinus Neoplasms; Otorhinolaryngologic Diseases

Extensive Research Description

Prospective, randomized trial identifying most efficacous nasal steroid for the management of nasal polyps.

Patient expectations regardiing sinus surgery

Clinical Trials

Conditions Study Title
Children's Health, Diseases of the Respiratory Systems Efficacy and Safety of OPN-375 186 ug Twice a Day (BID) in Adolescents with Bilateral Nasal Polyps
Lip, Oral Cavity and Pharynx Phase II Randomized Trial of Neo-Adjuvant Chemotherapy Followed by Surgery and Post-Operative Radiation Versus Surgery and Post-Operative Radiation for Organ Preservation of T3 and T4a Nasal and Paranasal Sinus Squamous Cell Carcinoma (NPNSCC)

Selected Publications

  • Ossifying fibroma of the nose and paranasal sinuses.

    Manes RP, Ryan MW, Batra PS, Mendelsohn D, Fang YV, Marple BF. Ossifying fibroma of the nose and paranasal sinuses. International Forum Of Allergy & Rhinology 2013, 3:161-8. 2013

  • Technical feasibility of endoscopic eustachian tube catheter placement: a cadaveric analysis.

    Manes RP, Kutz JW, Isaacson B, Batra PS. Technical feasibility of endoscopic eustachian tube catheter placement: a cadaveric analysis. American Journal Of Rhinology & Allergy 2013, 27:314-6. 2013

  • Sinonasal manifestations of sarcoidosis: a single institution experience with 38 cases.

    Aloulah M, Manes RP, Ng YH, Fitzgerald JE, Glazer CS, Ryan MW, Marple BF, Batra PS. Sinonasal manifestations of sarcoidosis: a single institution experience with 38 cases. International Forum Of Allergy & Rhinology 2013, 3:567-72. 2013

  • Prospective evaluation of aerosol delivery by a powered nasal nebulizer in the cadaver model.

    Manes RP, Tong L, Batra PS. Prospective evaluation of aerosol delivery by a powered nasal nebulizer in the cadaver model. International Forum Of Allergy & Rhinology 2011, 1:366-71. 2011

  • Prospective evaluation of intraoperative computed tomography imaging for endoscopic sinonasal and skull-base surgery.

    Batra PS, Manes RP, Ryan MW, Marple BF. Prospective evaluation of intraoperative computed tomography imaging for endoscopic sinonasal and skull-base surgery. International Forum Of Allergy & Rhinology 2011, 1:481-7. 2011

  • Utility of novel 3-dimensional stereoscopic vision system for endoscopic sinonasal and skull-base surgery.

    Manes RP, Barnett S, Batra PS. Utility of novel 3-dimensional stereoscopic vision system for endoscopic sinonasal and skull-base surgery. International Forum Of Allergy & Rhinology 2011, 1:191-7. 2011

  • Initial clinical experience with balloon dilation in revision frontal sinus surgery.

    Wycherly BJ, Manes RP, Mikula SK. Initial clinical experience with balloon dilation in revision frontal sinus surgery. The Annals Of Otology, Rhinology, And Laryngology 2010, 119:468-71. 2010

  • Evaluating and managing the patient with nosebleeds.

    Manes RP. Evaluating and managing the patient with nosebleeds. The Medical Clinics Of North America 2010, 94:903-12. 2010

  • Survival Outcomes for Combined Modality Therapy for Sinonasal Undifferentiated Carcinoma.

    Kuo P, Manes RP, Schwam ZG, Judson BL. Survival Outcomes for Combined Modality Therapy for Sinonasal Undifferentiated Carcinoma. Otolaryngology--head And Neck Surgery : Official Journal Of American Academy Of Otolaryngology-Head And Neck Surgery 2017, 156:132-136. 2017

  • Understanding patients' knowledge and expectations in endoscopic sinus surgery.

    15. Neubauer, P., F. Francis, A. Tabaee, Z. Schwam, and R.P. Manes. Understanding patients' knowledge and expectations in endoscopic sinus surgery. International Forum of Allergy and Rhinology 2016, 9:921-5 2016

  • Comparison of intranasal fluticasone and budesonide in post-operative endoscopic sinus surgery patients with chronic rhinosinusitis with polyposis: A randomized-controlled trial.

    14. Neubauer, P., Z. Schwam and R.P. Manes. Comparison of intranasal fluticasone and budesonide in post-operative endoscopic sinus surgery patients with chronic rhinosinusitis with polyposis: A randomized-controlled trial. International Forum of Allergy and Rhinology 2016, 6:233-7 2016

  • Superior oblique palsy: A complication of endoscopic sinus surgery.

    13. Lin, J.S., T.T. Liu, R.P. Manes and J.A. Galvin. Superior oblique palsy: A complication of endoscopic sinus surgery. Journal of AAPOS 2015, 19:180-1. 2015

  • Electromagnetic image guided orbital decompression: technique, principles and preliminary experience with 6 consecutive cases.

    12. Servat, J.J., M.D. Elia, D. Gong, R.P. Manes, E.H. Black and F. Levin. Electromagnetic image guided orbital decompression: technique, principles and preliminary experience with 6 consecutive cases. Orbit 2014, 33:433-6. 2014

  • Quality measurement for rhinosinusitis: a review from the Quality Improvement Committee of the American Rhinologic Society

    Rudmik L., Mattos J., Schneider J., R. P. Manes, Stokken J.A., Lee J., Higgins T.S., Schlosser R. J., Reh D.D., Setzen M., Soler Z.M. Quality measurement for rhinosinusitis: a review from the Quality Improvement Committee of the American Rhinologic Society. International Forum of Allergy and Rhinology 2017;7:853-60. 2017

  • Rhinology-specific Priority Setting for Quality Improvement: A Modified Delphi Study from the Quality Improvement Committee of the American Rhinologic Society

    Rudmik L., Mattos J., Schneider J., R. P. Manes, Stokken J.A., Lee J., Higgins T.S., Schlosser R. J., Reh D.D., Setzen M., Soler Z.M. Rhinology-specific Priority Setting for Quality Improvement: A Modified Delphi Study from the Quality Improvement Committee of the American Rhinologic Society. International Forum of Allergy and Rhinology 2018

  • Direct tumor embolization of sinonasal unclassified spindle cell carcinoma with Onyx

    Kansal, A., P. Srinet and R.P. Manes. Direct tumor embolization of sinonasal unclassified spindle cell carcinoma with Onyx. J Neurol Surg Rep 2016;77:139-43. 2016

See list of PubMed publications

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Contact Info

R Peter Manes, MD, FACS
Mailing Address
SurgeryPO Box 208062
New Haven, CT 06520-8062

Curriculum Vitae