Roy H. Decker, MD/PhD

Professor of Therapeutic Radiology; Disease Aligned Research Team Leader, Therapeutic Radiology, Yale Cancer Center; Director, Residency Training Program; Director, Thoracic/Stereotactic Body Radiotherapy Program; Vice Chair for Clinical Research

Research Departments & Organizations

Therapeutic Radiology

Radiobiology & Radiotherapy

Yale Cancer Center: Radiobiology & Radiotherapy

Office of Cooperative Research

Research Interests

Carcinoma, Non-Small-Cell Lung; Lung; Medical Oncology; Neoplasm Metastasis; Radiotherapy

Research Summary

I am a radiation oncologist focusing on the treatment of lung cancer and head and neck cancer, working at the Yale University School of Medicine, and the Smilow Cancer Hospital at Yale New Haven. I am a member of the Cancer Center’s Radiobiology & Radiotherapy Program. For early lung cancer, my research focus is based on the treatment of stage I or II NSCLC with SBRT. For advanced cancer, my research focus has been the addition of targeted agents concurrently with fractionated radiation, in an effort to increase the tumor radiation response, and in combining radiation with immunotherapy in metastatic disease.

Clinical Trials

Conditions Study Title
Lung Maintenance Systemic Therapy Versus Consolidative Stereotactic Body Radiation Therapy (SBRT) Plus Maintenance Systemic Therapy for Limited Metastatic Non-Small Cell Lung Cancer (NSCLC): A Randomized Phase II/III Trial
Larynx, Lip, Oral Cavity and Pharynx Single-Arm Phase II Trial of Dual Inhibition of EGFR With Afatinib and Cetuximab With Correlative Studies in the Second-Line Treatment of Recurrent or Metastatic Squamous Cell Cancers of the Head and Neck
Larynx, Lip, Oral Cavity and Pharynx, Ill-Defined Sites A Phase II Study of Pembrolizumab for Patients With Head and Neck Squamous Cell Carcinoma With Residual Disease Following Definitive Chemoradiation
Lung Randomized Phase II/III Trial of Prophylactic Cranial Irradiation With or Without Hippocampal Avoidance for Small Cell Lung Cancer
Larynx, Lip, Oral Cavity and Pharynx Phase II Randomized Trial of Adjuvant Radiotherapy With or Without Cisplatin for p53 Mutated, Surgically Resected Squamous Cell Carcinoma of the Head and Neck (SCCHN)

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Contact Info

Roy H. Decker, MD/PhD
Office Location
Yale Therapeutic RadiologyHunter Building
15 York Street, Ste HRT 134

New Haven, CT 06510
Mailing Address
Therapeutic RadiologyPO Box 208040
New Haven, CT 06520-8040