Peter Krause, MD

Senior Research Scientist in Epidemiology (Microbial Diseases), in Medicine (Infectious Diseases) and in Pediatrics (Infectious Disease) and Lecturer in Epidemiology (Microbial Diseases)

Research Departments & Organizations

School of Public Health: Epidemiology of Microbial Diseases

Infectious Diseases

Research Interests

Babesiosis; Blood Transfusion; Borrelia burgdorferi; Diseases; Epidemiology; Infectious Disease Medicine; Lyme Disease; Organisms; Relapsing Fever

Research Summary

Dr. Krause’s research interests are in vector borne diseases including babesiosis, Lyme disease and Borrelia miyamotoi, a relapsing fever spirochete. Current projects include babesiosis and Lyme disease persistence, co-infection, and geographic expansion; the host immunologic response to Babesia microti; prevention of transmission of babesiosis through blood transfusion; and human infection with Borrelia miyamotoi.

Specialized Terms: Vector borne diseases

Extensive Research Description

Dr. Krause’s research interests are in vector borne diseases including babesiosis, Lyme disease and Borrelia miyamotoi, a relapsing fever spirochete. Current projects include babesiosis and Lyme disease persistence, co-infection, and geographic expansion; the host immunologic response to Babesia microti; prevention of transmission of babesiosis through blood transfusion; and human infection with Borrelia miyamotoi.

Activities

  • Tick-borne Disease Research Obihiro, Japan; Moscow, Russia; New Haven, United States (2010)

    We have collaborated with Russian scientists to describe the first human cases of Borrelia miyamotoi relapsing fever infection. We are continuing research collaboration to better define the epidemiology, ecology, clinical manifestations, pathogenesis, diagnosis and treatment of this infection.

    We...

Selected Publications

  • Transfusion transmitted babesiosis. Is it time to screen the blood supply?

    Levin A, Krause PJ. Transfusion transmitted babesiosis. Is it time to screen the blood supply? Curr Opin Hematol, in press

  • Coinfection by Ixodes tick-borne pathogens: Ecological, epidemiological, and clinical consequences.

    Diuk-Wasser M, Vannier E, Krause PJ. Coinfection by Ixodes tick-borne pathogens: Ecological, epidemiological, and clinical consequences. Trends in Parasitol. 2016;32:30-42. 2016

  • Borrelia miyamotoi infection in nature and in humans.

    Krause PJ, Fish D, Narasimhan S, Barbour AG. Borrelia miyamotoi infection in nature and in humans. Clin Microbiol Infect. 2015;21:631-639.

  • Blood transfusion transmission of the tick-borne relapsing fever spirochete Borrelia miyamotoi in mice

    Krause PJ, Hendrickson J, Steeves T, Fish D. Transfusion 2015;55:593-7. 2015

  • Babesiosis in China, an emerging threat.

    Vannier E, Krause PJ. Babesiosis in China, an emerging threat. The Lancet. Infectious Diseases 2015, 15:137-9. 2015

  • Borrelia miyamotoi sensu lato seroreactivity and seroprevalence in the northeastern United States.

    Krause PJ, Narasimhan S, Wormser GP, Barbour AG, Platonov AE, Brancato J, Lepore T, Dardick K, Mamula M, Rollend L, Steeves TK, Diuk-Wasser M, Usmani-Brown S, Williamson P, Sarksyan DS, Fikrig E, Fish D. Borrelia miyamotoi sensu lato seroreactivity and seroprevalence in the northeastern United States. Emerging Infectious Diseases 2014, 20:1183-90. 2014

  • Human babesiosis.

    Vannier E, Krause PJ. Human babesiosis. The New England Journal Of Medicine 2012, 366:2397-407. 2012

  • Preventing transfusion-transmitted babesiosis: preliminary experience of the first laboratory-based blood donor screening program.

    Young C, Chawla A, Berardi V, Padbury J, Skowron G, Krause PJ. Preventing transfusion-transmitted babesiosis: preliminary experience of the first laboratory-based blood donor screening program. Transfusion 2012, 52:1523-9. 2012

  • Humans infected with relapsing fever spirochete Borrelia miyamotoi, Russia.

    Platonov AE, Karan LS, Kolyasnikova NM, Makhneva NA, Toporkova MG, Maleev VV, Fish D, Krause PJ. Humans infected with relapsing fever spirochete Borrelia miyamotoi, Russia. Emerging Infectious Diseases 2011, 17:1816-23. 2011

  • Increasing health burden of human babesiosis in endemic sites.

    Krause PJ, McKay K, Gadbaw J, Christianson D, Closter L, Lepore T, Telford SR, Sikand V, Ryan R, Persing D, Radolf JD, Spielman A. Increasing health burden of human babesiosis in endemic sites. The American Journal Of Tropical Medicine And Hygiene 2003, 68:431-6. 2003

  • Atovaquone and azithromycin for the treatment of babesiosis.

    Krause PJ, Lepore T, Sikand VK, Gadbaw J, Burke G, Telford SR, Brassard P, Pearl D, Azlanzadeh J, Christianson D, McGrath D, Spielman A. Atovaquone and azithromycin for the treatment of babesiosis. The New England Journal Of Medicine 2000, 343:1454-8. 2000

  • Persistent parasitemia after acute babesiosis.

    Krause PJ, Spielman A, Telford SR, Sikand VK, McKay K, Christianson D, Pollack RJ, Brassard P, Magera J, Ryan R, Persing DH. Persistent parasitemia after acute babesiosis. The New England Journal Of Medicine 1998, 339:160-5. 1998

See list of PubMed publications

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Contact Info

Peter Krause, MD
Office Location
60 College Street, Ste 604
New Haven, CT 06510
Mailing Address
Epidemiology of Microbial DiseasesPO Box 208034
60 College Street

New Haven, CT 06520-8034

Curriculum Vitae