Pamela Valentino, MD, MSc, FRCP(C)

Assistant Professor of Pediatrics (Gastroenterology)

Research Departments & Organizations

Pediatrics: Pediatric Gastroenterology & Hepatology

Research Interests

Biliary Tract Surgical Procedures; Cholangitis, Sclerosing; Gastroenterology; Inflammatory Bowel Diseases; Liver; Liver Transplantation; Pediatrics

Research Summary

Dr. Valentino’s two main research interests include: bile duct complications in children with liver transplants, as well as primary sclerosing cholangitis (PSC), an autoimmune bile duct disease.

The Yale New Haven Transplantation Center (YNHTC) is a member of the North American pediatric liver transplant group called Studies of Pediatric Liver Transplantation (SPLIT). This group has awarded Dr. Valentino and her colleagues funding to investigate the management of bile duct complications in children with liver transplants across the country.

Dr. Valentino is also investigating PSC, which occurs in 5% of children with inflammatory bowel disease (IBD). Unfortunately, 10-20% of children with PSC undergo liver transplantation. Dr. Valentino is investigating non-invasive means to identify PSC in children with IBD. Dr. Valentino is also involved in multicenter studies to help us understand PSC as well as the medications we can use in the treatment of this condition.

Clinical Trials

Conditions Study Title
Immune System, Infectious Diseases Multicenter, Open Label, Phase 3 Trial of ATA129 for Solid Organ Transplant Subjects With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure of Rituximab or Rituximab and Chemotherapy (ALLELE Study)
Diseases of the Digestive System - Liver, Diseases of the Eye, Diseases of the Nervous System Wilson Disease Registry

Selected Publications

See list of PubMed publications

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Contact Info

Pamela Valentino, MD, MSc, FRCP(C)
Mailing Address
Pediatric Gastroenterology & HepatologyYale School of Medicine
PO Box 208064

New Haven, CT 06520-8064