Murat Gunel, MD, FACS, FAHA, FAANS

Nixdorff-German Professor of Neurosurgery and Professor of Genetics and of Neuroscience; Chair, Department of Neurosurgery; Chief, Neurosurgery, Yale New Haven Health System; Chair, Perioperative Executive Leadership Committee; Director, Residency Program; Member, National Academy of Medicine; Co-Director, Yale Program on Neurogenetics

Research Departments & Organizations

Neurosurgery: Gunel Lab

Brain Tumor Research

Dean's Workshops

Interdepartmental Neuroscience Program

Vascular Biology and Therapeutics Program

Yale Cancer Center: Genomics, Genetics, and Epigenetics

Office of Cooperative Research

Research Interests

Aneurysm; Brain; Genetics; Hemangioma, Cavernous, Central Nervous System; Molecular Biology; Neurobiology; Neurosurgery

Research Summary

Within the Neurogenetics program, my lab has three major research interests: the first two relate to the molecular genetics and biology of hemorrhagic stroke, focusing on brain aneurysms and cavernous malformations, and the third centers on gene discovery in developmental structural brain disorders (cerebral malformations).

The overall approach of my lab is to start with a focus on gene discovery through modern, cutting edge molecular genetics and moving on to molecular biology and functional analysis of disease in order to design diagnostics and non-invasive novel treatments.

Specialized Terms: Molecular genetics and biology of brain aneurysms and cavernous malformations; Molecular genetics of brain development

Extensive Research Description

  • Molecular Genetics of Intracranial Aneurysms
  • Molecular Genetics and Biology of Cavernous Malformations
  • Cerebral Malformations in Developmental Structural Brain Disorders


  • Neurovascular Surgery Turkey (2008)

    Professor Gunel conducts collaborative work in Turkey on neurovascular surgery

  • Molecular Genetics Turkey (2007)

    Collaboration on genetics of malformations of brain development

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