Michael Kozal, MD

Professor of Medicine (AIDS); Vice Chair for Veteran Affairs, Yale Dept. of Internal Medicine; Chief, Medical Service, VACT Healthcare System; Medicine Service Line Director for VISN 1: VA New England Healthcare System

Research Departments & Organizations

Internal Medicine: Infectious Diseases

Virology Laboratories

Yale Cancer Center: Virus and Other Infection-associated Cancers

Office of Cooperative Research

Research Interests

Acquired Immunodeficiency Syndrome; Clinical Trials as Topic; Drug Resistance; Hepatitis C; HIV; Infectious Disease Medicine; Veterans

Research Summary

Dr. Kozal's major research interests are the genetic determinants of HIV and Hepatitis C drug resistance. Dr. Kozal’s lab uses new deep sequencing technologies to detect minority resistant viral variants in patients and study the impact of these resistant variants on clinical outcomes. Dr. Kozal is the Director of HIV Clinical Trials at Yale and the VA and he is the principal investigator on multiple HIV and Hepatitis C clinical trials.

Specialized Terms: Genetic determinants of HIV and Hepatitis C drug resistance; New technologies to detect low abundance drug resistant viral variants

Clinical Trials

Conditions Study Title
HIV/AIDS, Immune System, Infectious Diseases Study of PRO 140 SC as Single Agent Maintenance Therapy in Virally Suppressed Subjects With CCR5-tropic HIV-1 Infection
HIV/AIDS, Infectious Diseases Safety and Efficacy of Emtricitabine and Tenofovir Alafenamide (F/TAF) Fixed-Dose Combination Once Daily for Pre-Exposure Prophylaxis in Men and Transgender Women Who Have Sex With Men and Are At Risk of HIV-1 Infection
HIV/AIDS, Infectious Diseases Evaluating the Use of Pitavastatin to Reduce the Risk of Cardiovascular Disease in HIV-Infected Adults (REPRIEVE)

Selected Publications

See list of PubMed publications

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