Mark David Siegel, MD

Professor of Medicine (Pulmonary); Program Director, Internal Medicine Traditional Residency Program

Research Departments & Organizations

Internal Medicine: Pulmonary, Critical Care & Sleep Medicine

Office of Cooperative Research

Research Interests

Chronic Disease; Education, Medical, Graduate; Ethics, Medical; Pulmonary Medicine; Respiratory Distress Syndrome, Adult; Sepsis; Terminal Care

Research Summary

Dr. Mark Siegel, the Program Director of the Traditional Internal Medicine Residency, is involved in multiple clinical research studies. For several years he has participated in multicenter clinical research trials investigating new treatments for sepsis and acute respiratory distress syndrome (ARDS), in addition to other facets of critical illness. Dr. Siegel has mentored several research projects conducted with Yale trainees in areas such as the management of sepsis, end-of-life decision making, and psychiatric disorders in the next-of-kin of ICU patients.

Specialized Terms: Sepsis and ARDS treatments; Chronic illness; Ethics; End-of-life decision making

Extensive Research Description

I am interested in studying the factors that influence end-of-life decision making by ICU clinicians and the family members of critically ill patients. In conjunction with this I am interested in the emotional, religious, educational, and cognitive factors that influence how choices are made.

I also maintain a strong focus on new treatment strategies for ARDS and sepsis as well as a striving for a better understanding of the factors that underlie the pathogenesis and outcomes of critical illness


  • Critical Care San Salvador, El Salvador (2009 - 2009)

    Visiting Professor

  • Critical Care Iran (2004 - 2004)

    Lecture Series, Pulmonary Conference

Selected Publications

See list of PubMed publications

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