Jui Dave, PhD

Postdoctoral Associate

Research Departments & Organizations

Greif Lab

Research Interests

Cardiovascular Diseases; Chromosome Disorders; Fetal Diseases; Genetic Diseases, Inborn; Heart Defects, Congenital; Infant, Newborn, Diseases; Vascular Malformations

Extensive Research Description

Current project is aimed at understanding key molecular mechanisms responsible for intracerebral hemorrhage (ICH) and elucidating the role of transforming growth factor beta-mediated signaling in this vascular disorder. ICH is caused by a marked disruption of the blood brain barrier, which in the murine embryonic brain, is comprised of endothelial cells, basement membrane and mural cells known as pericytes. The overall goal of this project is to identify molecular targets and devise novel therapeutic strategies to reduce the incidence and morbidity of neonatal ICH.

Selected Publications

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