Research Departments & Organizations
As a general internist and clinical epidemiologist, Dr. Concato conducts research to address questions related to screening, prognosis, and treatment strategies, as well as to improve methods of study design and statistical analysis. This dual focus has involved a range of topics in both patient care and research methodology. Examples include evaluating the effectiveness of screening for prostate cancer, studies of prognosis in prostate cancer, comparing the results of observational studies and randomized trials, and clarifying the use of multivariable analysis in patient-oriented research. More recent (“center-based”) research includes projects in genomic medicine, as part of the VA Cooperative Studies Program and Genomic Medicine Program.
Specialized Terms: Screening, prognosis, and treatment strategies; improving methods of research design and statistical analysis
Study design and "evidence" in patient-oriented research.
Concato J. Study design and "evidence" in patient-oriented research. American Journal Of Respiratory And Critical Care Medicine 2013, 187:1167-72. 2013
Probability, uncertainty, and prostate cancer.
Concato J. Probability, uncertainty, and prostate cancer. Annals Of Internal Medicine 2013, 158:211-212. 2013
Is it time for medicine-based evidence?
Concato J. Is it time for medicine-based evidence? JAMA 2012, 307:1641-3. 2012
Observational methods in comparative effectiveness research.
Concato J, Lawler EV, Lew RA, Gaziano JM, Aslan M, Huang GD. Observational methods in comparative effectiveness research. The American Journal Of Medicine 2010, 123:e16-23. 2010
The effectiveness of screening for prostate cancer: a nested case-control study.
Concato J, Wells CK, Horwitz RI, Penson D, Fincke G, Berlowitz DR, Froehlich G, Blake D, Vickers MA, Gehr GA, Raheb NH, Sullivan G, Peduzzi P. The effectiveness of screening for prostate cancer: a nested case-control study. Archives Of Internal Medicine 2006, 166:38-43. 2006
Randomized, controlled trials, observational studies, and the hierarchy of research designs.
Concato J, Shah N, Horwitz RI. Randomized, controlled trials, observational studies, and the hierarchy of research designs. The New England Journal Of Medicine 2000, 342:1887-92. 2000
Million Veteran Program (MVP): a mega-biobank to study genetic influences on health and disease
160. Gaziano M, Concato J, Brophy M, Fiore L, Pyarajan S, Breeling J, Whitbourne S, Deen J, Shannon C, Humphries D, Guarino P, Aslan M, Anderson D, LaFleur R, Hammond T, Schaa K, Moser J, Huang G, Muralidhar S, Przygodzki R, O’Leary TJ. J Clin Epidemiol 2016;70:214-223. 2016