James V. Freeman, MD

Associate Professor of Medicine (Cardiology)

Research Departments & Organizations

Internal Medicine: Cardiovascular Medicine: Center for Outcomes Research & Evaluation (CORE)

Office of Cooperative Research

Research Interests

Arrhythmias, Cardiac; Atrial Flutter; Cardiology; Defibrillators, Implantable; Health Care Quality, Access, and Evaluation; Heart Arrest; Quality of Health Care; Ventricular Fibrillation

Research Summary

I am a clinical cardiac electrophysiologist, and I study the comparative effectiveness, cost-effectiveness and clinical outcomes associated with cardiac arrhythmias and their treatments. , cardiac electrophysiology and exercise physiology. I have an NIH funded career development award (K23) to study the comparative effectiveness of ablation for atrial fibrillation compared with medical therapy for the prevention of long term adverse outcomes such as death and ischemic stroke. I am also conducting research sponsored by the American Heart Association and industry focused on ICD therapy, heart failure, and atrial fibrillation.

Specialized Terms: Arrhythmias; atrial fibrillation; atrial flutter; ventricular tachycardia; ventricular fibrillation; implantable cardioverter-defibrillator; cardiac ablation; outcomes research; cost-effectiveness

Extensive Research Description

1) Comparative effectiveness of catheter ablation vs medical therapy for atrial fibrillation

2) Symptoms associated with atrial fibrillation in patients in the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF)

3) Contemporary comparative effectiveness of implantable cardioverter-defibrillators vs medical therapy for decreasing mortality

Clinical Trials

Conditions Study Title
Diseases of the Cardiovascular System Strategic Management to Improve CRT Using Multi-Site Pacing Post Approval Study (Reference # C1918) (SMARTMSP)
Diseases of the Cardiovascular System REDUCE LAP-HF II
Diseases of the Cardiovascular System aMAZE Study: LAA Ligation Adjunctive to PVI for Persistent or Longstanding Persistent Atrial Fibrillation (aMAZE)

Selected Publications

See list of PubMed publications

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Contact Info

James V. Freeman, MD
Mailing Address
Cardiovascular Medicine789 Howard Avenue
PO Box 208017

New Haven, CT 06520-8017

Curriculum Vitae