Henry S. Park, MD, MPH

Assistant Professor of Therapeutic Radiology

Research Departments & Organizations

Therapeutic Radiology

Yale Cancer Center: Radiobiology & Radiotherapy

Research Summary

As a radiation oncologist and epidemiologist, my research focuses on evaluating determinants of population-based outcomes, health services utilization, and medical decision-making for patients with cancer. I have used national and institutional observational databases as well as systematic reviews and meta-analyses to gain insight into how clinical, demographic, and health system factors affect quality of care and outcomes for this vulnerable population. I also highly prioritize the use of innovative statistical methods to minimize the inherent biases of retrospective analysis, having led the development of a tool known as sequential landmark analysis to control for immortal time bias when interpreting observational analyses studying the survival impact of adjuvant radiation therapy. I have directed the Yale Radiation Oncology Consortium (YROC) and have collaborated closely with the Yale Cancer Outcomes, Public Policy, and Effectiveness Research Center (COPPER). I am also interested in mentoring medical students and residents in comparative effectiveness and health services research.

Clinical Trials

Conditions Study Title
Other Skin A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate Pembrolizumab Versus Placebo as Adjuvant Therapy Following Surgery and Radiation in Participants With High-risk Locally Advanced Cutaneous Squamous Cell Carcinoma (LA cSCC) (KEYNOTE-630)
Prostate Randomized Phase II Study of Salvage XRT + ADT +/- Abiraterone Acetate and Apalutamide (ARN-509) for Rising PSA After Radical Prostatectomy With Adverse Features.(FORMULA-509 Trial)
Breast - Female Study of Radiation Fractionation on Patient Outcomes After Breast REConstruction (FABREC) for Invasive Breast Carcinoma
Esophagus, Larynx, Lip, Oral Cavity and Pharynx Randomized Phase II/III Trial of Radiotherapy With Concurrent MEDI4736 (Durvalumab) vs. Radiotherapy With Concurrent Cetuximab in Patients With Locoregionally Advanced Head and Neck Cancer With a Contraindication to Cisplatin
Breast - Female, Breast TAILOR RT: A Randomized Trial of Regional Radiotherapy in Biomarker Low Risk Node Positive Breast Cancer
Larynx, Lip, Oral Cavity and Pharynx A Phase I Study of M6620 (VX-970) in Combination With Cisplatin and XRT in Patients With Locally Advanced HPV (-) Head and Neck Squamous Cell Carcinoma (HNSCC; SDC 10060121)
Lip, Oral Cavity and Pharynx Phase II Randomized Trial of Neo-Adjuvant Chemotherapy Followed by Surgery and Post-Operative Radiation Versus Surgery and Post-Operative Radiation for Organ Preservation of T3 and T4a Nasal and Paranasal Sinus Squamous Cell Carcinoma (NPNSCC)
Prostate Phase III IGRT and SBRT vs IGRT and Hypofractionated IMRT for Localized Intermediate Risk Prostate Cancer
Lung Maintenance Systemic Therapy Versus Consolidative Stereotactic Body Radiation Therapy (SBRT) Plus Maintenance Systemic Therapy for Limited Metastatic Non-Small Cell Lung Cancer (NSCLC): A Randomized Phase II/III Trial
Other Skin A Phase 2, Open-Label, Single Arm Study to Evaluate the Safety and Efficacy of Pembrolizumab in Participants With Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma (R/M cSCC)
Larynx, Lip, Oral Cavity and Pharynx, Ill-Defined Sites A Phase II Study of Pembrolizumab for Patients With Head and Neck Squamous Cell Carcinoma With Residual Disease Following Definitive Chemoradiation
Lung Randomized Phase II/III Trial of Prophylactic Cranial Irradiation With or Without Hippocampal Avoidance for Small Cell Lung Cancer
Larynx, Lip, Oral Cavity and Pharynx Phase II Randomized Trial of Adjuvant Radiotherapy With or Without Cisplatin for p53 Mutated, Surgically Resected Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Lip, Oral Cavity and Pharynx Individualized Treatment in Treating Patients With Stage II-IVB Nasopharyngeal Cancer Based on EBV DNA

Edit this profile

Contact Info

Henry S. Park, MD, MPH
Office Location
Smilow Cancer Hospital at Yale New Haven
35 Park Street, Rm Lower Level 513

New Haven, CT 06511